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- W2002620488 endingPage "S191" @default.
- W2002620488 startingPage "S184" @default.
- W2002620488 abstract "Mantle cell lymphoma (MCL) still carries a poor prognosis. Chemoimmunotherapy (combination with rituximab) is the routine first-line therapy, although data strongly suggest a benefit from intensification through high-dose therapy with stem cell transplantation consolidation or doseintense chemotherapy with HyperCVAD (fractionated cyclophosphamide/vincristine/doxorubicin/dexamethasone)/rituximab. Unfortunately, most patients still experience relapse, and a multitude of novel agents are currently being tested in this setting, including proteasome inhibitors with bortezomib (the first of its class and first Food and Drug Administration–approved drug in MCL), mammalian target of rapamycin inhibitors, Bcl-2 inhibitors, and antiangiogenesis agents, among others. Because of the relative rarity of the disease—MCL represents 6% of non-Hodgkin lymphoma—an obvious effort is needed to enroll patients on clinical trials. Not surprisingly, as in other non-Hodgkin lymphomas, MCL appears more and more as a heterogeneous disease, which might impact future clinical trial design through pharmacogenomics and hopefully help us develop smaller “molecular” relevant trials." @default.
- W2002620488 created "2016-06-24" @default.
- W2002620488 creator A5051138695 @default.
- W2002620488 creator A5089882481 @default.
- W2002620488 date "2007-08-01" @default.
- W2002620488 modified "2023-09-24" @default.
- W2002620488 title "Expanding Therapeutic Options in Mantle Cell Lymphoma" @default.
- W2002620488 cites W148711857 @default.
- W2002620488 cites W1533512270 @default.
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- W2002620488 cites W1963571549 @default.
- W2002620488 cites W1970346572 @default.
- W2002620488 cites W1970384544 @default.
- W2002620488 cites W1977070131 @default.
- W2002620488 cites W1980575012 @default.
- W2002620488 cites W1982330025 @default.
- W2002620488 cites W1982740352 @default.
- W2002620488 cites W1984737539 @default.
- W2002620488 cites W1998236108 @default.
- W2002620488 cites W2002858168 @default.
- W2002620488 cites W2009656063 @default.
- W2002620488 cites W2010436796 @default.
- W2002620488 cites W2011102246 @default.
- W2002620488 cites W2017898416 @default.
- W2002620488 cites W2021695924 @default.
- W2002620488 cites W2027362911 @default.
- W2002620488 cites W2027395744 @default.
- W2002620488 cites W2033761235 @default.
- W2002620488 cites W2036242721 @default.
- W2002620488 cites W2041423582 @default.
- W2002620488 cites W2041438500 @default.
- W2002620488 cites W2059410730 @default.
- W2002620488 cites W2063779563 @default.
- W2002620488 cites W2065452964 @default.
- W2002620488 cites W2066052727 @default.
- W2002620488 cites W2067653691 @default.
- W2002620488 cites W2074610455 @default.
- W2002620488 cites W2075844712 @default.
- W2002620488 cites W2086765333 @default.
- W2002620488 cites W2095520712 @default.
- W2002620488 cites W2100608938 @default.
- W2002620488 cites W2102986716 @default.
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- W2002620488 cites W2107040737 @default.
- W2002620488 cites W2108063064 @default.
- W2002620488 cites W2108242165 @default.
- W2002620488 cites W2108519805 @default.
- W2002620488 cites W2114829898 @default.
- W2002620488 cites W2116090592 @default.
- W2002620488 cites W2119680582 @default.
- W2002620488 cites W2123185965 @default.
- W2002620488 cites W2125684345 @default.
- W2002620488 cites W2130883918 @default.
- W2002620488 cites W2131491521 @default.
- W2002620488 cites W2131998596 @default.
- W2002620488 cites W2138278557 @default.
- W2002620488 cites W2139582914 @default.
- W2002620488 cites W2144863760 @default.
- W2002620488 cites W2147422161 @default.
- W2002620488 cites W2147538082 @default.
- W2002620488 cites W2150871719 @default.
- W2002620488 cites W2153569820 @default.
- W2002620488 cites W2153859516 @default.
- W2002620488 cites W2155724413 @default.
- W2002620488 cites W2156451974 @default.
- W2002620488 cites W2162903487 @default.
- W2002620488 cites W2163790170 @default.
- W2002620488 cites W2169064989 @default.
- W2002620488 cites W2223116323 @default.
- W2002620488 cites W2250133118 @default.
- W2002620488 cites W2254608986 @default.
- W2002620488 cites W2258467532 @default.
- W2002620488 cites W2275219352 @default.
- W2002620488 cites W2305957322 @default.
- W2002620488 cites W2324395577 @default.
- W2002620488 cites W2330094776 @default.
- W2002620488 cites W2336409148 @default.
- W2002620488 cites W2342397384 @default.
- W2002620488 cites W2550573620 @default.
- W2002620488 cites W2551721461 @default.
- W2002620488 cites W2556085825 @default.
- W2002620488 cites W2567526623 @default.
- W2002620488 cites W2585372326 @default.
- W2002620488 cites W2587772896 @default.
- W2002620488 cites W2599885625 @default.
- W2002620488 cites W2958564469 @default.
- W2002620488 cites W2994379879 @default.
- W2002620488 cites W4241904210 @default.
- W2002620488 cites W4293770031 @default.
- W2002620488 doi "https://doi.org/10.3816/clm.2007.s.021" @default.
- W2002620488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17877843" @default.
- W2002620488 hasPublicationYear "2007" @default.
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