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• W2002662423 abstract "The distalless-related homeogene Dlx5 is expressed in the olfactory placodes and derived tissues and in the anterior-basal forebrain. We investigated the role of Dlx5 in olfactory development. In Dlx5−/− mice, the olfactory bulbs (OBs) lack glomeruli, exhibit disorganized cellular layers, and show reduced numbers of TH- and GAD67-positive neurons. The olfactory epithelium in Dlx5−/− mice is composed of olfactory receptor neurons (ORNs) that appear identical to wild-type ORNs, but their axons fail to contact the OBs. We transplanted Dlx5−/− OBs into a wild-type newborn mouse; wild-type ORN axons enter the mutant OB and form glomeruli, but cannot rescue the lamination defect or the expression of TH and GAD67. Thus, the absence of Dlx5 in the OB does not per se prevent ORN axon ingrowth. In conclusion, Dlx5 plays major roles in the connectivity of ORN axons and in the differentiation of OB interneurons." @default.
• W2002662423 created "2016-06-24" @default.
• W2002662423 creator A5035753887 @default.
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• W2002662423 creator A5076684486 @default.
• W2002662423 creator A5081918772 @default.
• W2002662423 date "2003-04-01" @default.
• W2002662423 modified "2023-10-12" @default.
• W2002662423 title "The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse" @default.
• W2002662423 cites W1553066467 @default.
• W2002662423 cites W1570521101 @default.
• W2002662423 cites W1611957532 @default.
• W2002662423 cites W1750082824 @default.
• W2002662423 cites W1819949295 @default.
• W2002662423 cites W1858323226 @default.
• W2002662423 cites W1867551029 @default.
• W2002662423 cites W1904057448 @default.
• W2002662423 cites W1947231608 @default.
• W2002662423 cites W1964796797 @default.
• W2002662423 cites W1966878243 @default.
• W2002662423 cites W1970256374 @default.
• W2002662423 cites W1980298497 @default.
• W2002662423 cites W1980500780 @default.
• W2002662423 cites W1985409830 @default.
• W2002662423 cites W1987301535 @default.
• W2002662423 cites W1987452519 @default.
• W2002662423 cites W1991745061 @default.
• W2002662423 cites W1993310108 @default.
• W2002662423 cites W1995651633 @default.
• W2002662423 cites W1996647995 @default.
• W2002662423 cites W1999224926 @default.
• W2002662423 cites W1999756818 @default.
• W2002662423 cites W2000061396 @default.
• W2002662423 cites W2000574570 @default.
• W2002662423 cites W2000955502 @default.
• W2002662423 cites W2007272533 @default.
• W2002662423 cites W2008118471 @default.
• W2002662423 cites W2014260701 @default.
• W2002662423 cites W2015038624 @default.
• W2002662423 cites W2016441749 @default.
• W2002662423 cites W2017855619 @default.
• W2002662423 cites W2019997163 @default.
• W2002662423 cites W2023195093 @default.
• W2002662423 cites W2028754060 @default.
• W2002662423 cites W2028791419 @default.
• W2002662423 cites W2031111711 @default.
• W2002662423 cites W2031912570 @default.
• W2002662423 cites W2035815744 @default.
• W2002662423 cites W2040945776 @default.
• W2002662423 cites W2041566392 @default.
• W2002662423 cites W2052065200 @default.
• W2002662423 cites W2056035698 @default.
• W2002662423 cites W2059614045 @default.
• W2002662423 cites W2060270022 @default.
• W2002662423 cites W2061172411 @default.
• W2002662423 cites W2062758517 @default.
• W2002662423 cites W2064624464 @default.
• W2002662423 cites W2067077186 @default.
• W2002662423 cites W2069186336 @default.
• W2002662423 cites W2071209050 @default.
• W2002662423 cites W2073288043 @default.
• W2002662423 cites W2075620680 @default.
• W2002662423 cites W2075683755 @default.
• W2002662423 cites W2085406711 @default.
• W2002662423 cites W2089598622 @default.
• W2002662423 cites W2093618328 @default.
• W2002662423 cites W2096060803 @default.
• W2002662423 cites W2098406706 @default.
• W2002662423 cites W2104789206 @default.
• W2002662423 cites W2108327191 @default.
• W2002662423 cites W2110313558 @default.
• W2002662423 cites W2113471324 @default.
• W2002662423 cites W2117824720 @default.
• W2002662423 cites W2121971226 @default.
• W2002662423 cites W2127535417 @default.
• W2002662423 cites W2135144225 @default.
• W2002662423 cites W2140735384 @default.
• W2002662423 cites W2148316867 @default.
• W2002662423 cites W2148339830 @default.
• W2002662423 cites W2155742892 @default.
• W2002662423 cites W2161830534 @default.
• W2002662423 cites W2167871684 @default.
• W2002662423 cites W2169436449 @default.
• W2002662423 cites W4254060662 @default.
• W2002662423 cites W4295274060 @default.
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• W2002662423 doi "https://doi.org/10.1016/s1044-7431(02)00041-6" @default.
• W2002662423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12727448" @default.
• W2002662423 hasPublicationYear "2003" @default.
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