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• W2002716405 abstract "Biologic agents (BAs) are important therapeutic tools; their use has rapidly expanded and they are used in oncology, immunology, and inflammatory diseases. Their use may be limited, however, by adverse drug reactions. This article reviews the current literature on clinical presentation and pathogenic mechanisms of both acute and delayed reactions. In addition, procedures for management of BA-induced reactions, including preventive and diagnostic work-up, are provided. Lastly, this article summarizes the current knowledge of desensitization to several widely used monoclonal antibodies." @default.
• W2002716405 created "2016-06-24" @default.
• W2002716405 creator A5004318668 @default.
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• W2002716405 date "2014-08-01" @default.
• W2002716405 modified "2023-09-23" @default.
• W2002716405 title "Hypersensitivity Reactions to Biologic Agents" @default.
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• W2002716405 doi "https://doi.org/10.1016/j.iac.2014.04.008" @default.
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