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• W2002795087 abstract "PURPOSE: A sensorless flow estimation algorithm is under development for HeartMate III, a centrifugal LVAD featuring a magnetically levitated impeller. The goal of this feasibility study was to characterize the accuracy of the method in vitro and to demonstrate its stability in a chronic in vivo study. METHODS: The flow estimation algorithm is based on knowledge of the power vs. flow curves of the pump. Its input values are pump speed, torque-building motor current, and the measured or assumed fluid viscosity and density. Steady flow studies were conducted in vitro using both water/glycerol solutions and bovine blood. Unsteady flow studies were conducted during a 27-day bovine implant. RESULTS: Pump flow estimates were accurate to within ± 0.3 Ipm (for positive flows ≤ 3 lpm) or 10% (for flows > 3 lpm) across the 0–12 Ipm flow range when viscosity is held constant. At the 5 Ipm operating point, the influence of viscosity on the flow estimate is 0.4 Ipm per centipoise. The algorithm was quite stable over the duration of the in vivo study. CONCLUSION: Our sensorless flow estimator has been shown feasible. Clinically, the algorithm would not require calibration for daily variation in hematocrit, although there may be cause for peri-operative calibration when the patient's hematocrit can be low and the clinician's need for low-flow accuracy high." @default.
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• W2002795087 date "2002-03-01" @default.
• W2002795087 modified "2023-09-30" @default.
• W2002795087 title "HEARTMATE III" @default.
• W2002795087 doi "https://doi.org/10.1097/00002480-200203000-00130" @default.
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