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- W2002802254 abstract "In patients who show diffuse or general ized loss o f alveolar bone, constitutional disease is often suspected. Painstaking in vestigations, which have included chemi cal and metabolic studies o f blood, urine and tissues1-6 have failed, however, to es tablish a strong case for a systemic back ground in periodontosis. Since the tissues which are involved— bone, periodontal membrane and cementum— are connec tive tissues, this study was made in the be lief that the disease might be related to some general process in connective tissue. There is mounting evidence that varia tions in the level o f at least one o f the serum glycoprotein fractions, seromucoid, may reflect changes in connective tissue ground substance, representing the dif fusible components o f the carbohydrateprotein complexes.7-12 Therefore, sero mucoid levels, measured as the bound hexose, were determined in a group of normal persons and in a corresponding group o f patients exhibiting general loss o f alveolar bone. T he blood level o f this glycoprotein was shown to be elevated in over 40 per cent o f the patients with peri odontosis." @default.
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- W2002802254 date "1958-12-01" @default.
- W2002802254 modified "2023-09-27" @default.
- W2002802254 title "Elevation of a serum glycoprotein in periodontosis" @default.
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- W2002802254 doi "https://doi.org/10.14219/jada.archive.1958.0217" @default.
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