Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002802558> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2002802558 endingPage "415" @default.
- W2002802558 startingPage "394" @default.
- W2002802558 abstract "The unusual life cycle of Dictyostelium discoideum, in which an extra-cellular stressor such as starvation induces the development of a multicellular fruiting body consisting of stalk cells and spores from a culture of identical amoebae, provides an excellent model for investigating the molecular control of differentiation and the transition from single- to multi-cellular life, a key transition in development. We utilized serial analysis of gene expression (SAGE), a molecular method that is unbiased by dependence on previously identified genes, to obtain a transcriptome from a high-density culture of amoebae, in order to examine the transition to multi-cellular development. The SAGE method provides relative expression levels, which allows us to rank order the expressed genes. We found that a large number of ribosomal proteins were expressed at high levels, while various components of the proteosome were expressed at low levels. The only identifiable transmembrane signaling system components expressed in amoebae are related to quorum sensing, and their expression levels were relatively low. The most highly expressed gene in the amoeba transcriptome, dutA untranslated RNA, is a molecule with unknown function that may serve as an inhibitor of translation. These results suggest that high-density amoebae have not initiated development, and they also suggest a mechanism by which the transition into the development program is controlled." @default.
- W2002802558 created "2016-06-24" @default.
- W2002802558 creator A5009309771 @default.
- W2002802558 creator A5022748494 @default.
- W2002802558 creator A5035401792 @default.
- W2002802558 creator A5091832483 @default.
- W2002802558 date "2010-01-01" @default.
- W2002802558 modified "2023-10-10" @default.
- W2002802558 title "Identifying the molecular basis of functions in the transcriptome of the social amoeba Dictyostelium discoideum" @default.
- W2002802558 cites W1586580669 @default.
- W2002802558 cites W1964405935 @default.
- W2002802558 cites W1971185254 @default.
- W2002802558 cites W1989699661 @default.
- W2002802558 cites W2001443734 @default.
- W2002802558 cites W2012844271 @default.
- W2002802558 cites W2026279251 @default.
- W2002802558 cites W2030290318 @default.
- W2002802558 cites W2033905712 @default.
- W2002802558 cites W2035740558 @default.
- W2002802558 cites W2069125601 @default.
- W2002802558 cites W2074308942 @default.
- W2002802558 cites W2094019194 @default.
- W2002802558 cites W2094089605 @default.
- W2002802558 cites W2101572684 @default.
- W2002802558 cites W2102539783 @default.
- W2002802558 cites W2136952612 @default.
- W2002802558 cites W2141805254 @default.
- W2002802558 cites W2151513534 @default.
- W2002802558 cites W2152768694 @default.
- W2002802558 cites W2156690217 @default.
- W2002802558 cites W2173713067 @default.
- W2002802558 cites W2490070288 @default.
- W2002802558 cites W4213387068 @default.
- W2002802558 doi "https://doi.org/10.4238/vol9-1gmr752" @default.
- W2002802558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20309825" @default.
- W2002802558 hasPublicationYear "2010" @default.
- W2002802558 type Work @default.
- W2002802558 sameAs 2002802558 @default.
- W2002802558 citedByCount "6" @default.
- W2002802558 countsByYear W20028025582013 @default.
- W2002802558 countsByYear W20028025582014 @default.
- W2002802558 countsByYear W20028025582023 @default.
- W2002802558 crossrefType "journal-article" @default.
- W2002802558 hasAuthorship W2002802558A5009309771 @default.
- W2002802558 hasAuthorship W2002802558A5022748494 @default.
- W2002802558 hasAuthorship W2002802558A5035401792 @default.
- W2002802558 hasAuthorship W2002802558A5091832483 @default.
- W2002802558 hasBestOaLocation W20028025581 @default.
- W2002802558 hasConcept C104317684 @default.
- W2002802558 hasConcept C105580179 @default.
- W2002802558 hasConcept C149364088 @default.
- W2002802558 hasConcept C150194340 @default.
- W2002802558 hasConcept C162317418 @default.
- W2002802558 hasConcept C2775889303 @default.
- W2002802558 hasConcept C2775969001 @default.
- W2002802558 hasConcept C2776172558 @default.
- W2002802558 hasConcept C54355233 @default.
- W2002802558 hasConcept C74318829 @default.
- W2002802558 hasConcept C86803240 @default.
- W2002802558 hasConcept C95444343 @default.
- W2002802558 hasConceptScore W2002802558C104317684 @default.
- W2002802558 hasConceptScore W2002802558C105580179 @default.
- W2002802558 hasConceptScore W2002802558C149364088 @default.
- W2002802558 hasConceptScore W2002802558C150194340 @default.
- W2002802558 hasConceptScore W2002802558C162317418 @default.
- W2002802558 hasConceptScore W2002802558C2775889303 @default.
- W2002802558 hasConceptScore W2002802558C2775969001 @default.
- W2002802558 hasConceptScore W2002802558C2776172558 @default.
- W2002802558 hasConceptScore W2002802558C54355233 @default.
- W2002802558 hasConceptScore W2002802558C74318829 @default.
- W2002802558 hasConceptScore W2002802558C86803240 @default.
- W2002802558 hasConceptScore W2002802558C95444343 @default.
- W2002802558 hasIssue "1" @default.
- W2002802558 hasLocation W20028025581 @default.
- W2002802558 hasLocation W20028025582 @default.
- W2002802558 hasOpenAccess W2002802558 @default.
- W2002802558 hasPrimaryLocation W20028025581 @default.
- W2002802558 hasRelatedWork W189934859 @default.
- W2002802558 hasRelatedWork W1999131104 @default.
- W2002802558 hasRelatedWork W2034720620 @default.
- W2002802558 hasRelatedWork W2068967068 @default.
- W2002802558 hasRelatedWork W2097676947 @default.
- W2002802558 hasRelatedWork W2277741384 @default.
- W2002802558 hasRelatedWork W2279887809 @default.
- W2002802558 hasRelatedWork W247369369 @default.
- W2002802558 hasRelatedWork W4310876791 @default.
- W2002802558 hasRelatedWork W1762192356 @default.
- W2002802558 hasVolume "9" @default.
- W2002802558 isParatext "false" @default.
- W2002802558 isRetracted "false" @default.
- W2002802558 magId "2002802558" @default.
- W2002802558 workType "article" @default.