Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002803706> ?p ?o ?g. }
- W2002803706 endingPage "414" @default.
- W2002803706 startingPage "401" @default.
- W2002803706 abstract "Using microdialysis, the effects of endogenous glutamate on extracellular concentrations of taurine, in striatum and nucleus accumbens of the awake rat during the normal process of aging were investigated. The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylic acid (PDC) was perfused through the microdialysis probe to increase the endogenous concentration of glutamate. Young (2-4 months), middle aged (12-14 months), aged (27-32 months) and very aged (37 months) male Wistar rats were used. PDC (1, 2 and 4 mM) produced a dose-related increase of extracellular concentrations of glutamate and taurine in striatum and nucleus accumbens in all groups of age. Increases of glutamate, but not of taurine, decreased during aging in striatum. In nucleus accumbens there were no age-related changes in the increases of glutamate and taurine induced by PDC. In all age groups, increases of extracellular taurine were significantly correlated with increases of extracellular glutamate. However, when these taurine-glutamate correlations for all groups of age were compared, no statistical differences were found. These results show first that a decrease in the increases of glutamate produced by the glutamate reuptake inhibitor in striatum, but not in nucleus accumbens, is produced by age; second that glutamate-taurine interaction in striatum and nucleus accumbens does not change during the normal process of aging." @default.
- W2002803706 created "2016-06-24" @default.
- W2002803706 creator A5003344696 @default.
- W2002803706 creator A5056030840 @default.
- W2002803706 creator A5065414106 @default.
- W2002803706 creator A5088480770 @default.
- W2002803706 date "2001-04-01" @default.
- W2002803706 modified "2023-10-01" @default.
- W2002803706 title "Endogenous glutamate–taurine interaction in striatum and nucleus accumbens of the freely moving rat: studies during the normal process of aging" @default.
- W2002803706 cites W1585708861 @default.
- W2002803706 cites W1605408170 @default.
- W2002803706 cites W1966073774 @default.
- W2002803706 cites W1972611197 @default.
- W2002803706 cites W1977626871 @default.
- W2002803706 cites W1981748579 @default.
- W2002803706 cites W1985931825 @default.
- W2002803706 cites W1987586697 @default.
- W2002803706 cites W1989422254 @default.
- W2002803706 cites W1990198870 @default.
- W2002803706 cites W1992713633 @default.
- W2002803706 cites W1993463589 @default.
- W2002803706 cites W1998247213 @default.
- W2002803706 cites W2002712349 @default.
- W2002803706 cites W2003926671 @default.
- W2002803706 cites W2010214511 @default.
- W2002803706 cites W2015171160 @default.
- W2002803706 cites W2016444389 @default.
- W2002803706 cites W2018266101 @default.
- W2002803706 cites W2021408139 @default.
- W2002803706 cites W2022233762 @default.
- W2002803706 cites W2024133614 @default.
- W2002803706 cites W2024277812 @default.
- W2002803706 cites W2027721538 @default.
- W2002803706 cites W2028119312 @default.
- W2002803706 cites W2032316395 @default.
- W2002803706 cites W2035750459 @default.
- W2002803706 cites W2037477787 @default.
- W2002803706 cites W2037918928 @default.
- W2002803706 cites W2046157170 @default.
- W2002803706 cites W2050846987 @default.
- W2002803706 cites W2053153052 @default.
- W2002803706 cites W2054683291 @default.
- W2002803706 cites W2058766494 @default.
- W2002803706 cites W2062860475 @default.
- W2002803706 cites W2064825321 @default.
- W2002803706 cites W2066190588 @default.
- W2002803706 cites W2066562577 @default.
- W2002803706 cites W2066931745 @default.
- W2002803706 cites W2067194771 @default.
- W2002803706 cites W2067261800 @default.
- W2002803706 cites W2075276022 @default.
- W2002803706 cites W2079112263 @default.
- W2002803706 cites W2083156858 @default.
- W2002803706 cites W2086167522 @default.
- W2002803706 cites W2087593804 @default.
- W2002803706 cites W2100453073 @default.
- W2002803706 cites W2128744963 @default.
- W2002803706 cites W215762041 @default.
- W2002803706 cites W313604520 @default.
- W2002803706 cites W73331426 @default.
- W2002803706 doi "https://doi.org/10.1016/s0047-6374(00)00252-9" @default.
- W2002803706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11240162" @default.
- W2002803706 hasPublicationYear "2001" @default.
- W2002803706 type Work @default.
- W2002803706 sameAs 2002803706 @default.
- W2002803706 citedByCount "10" @default.
- W2002803706 countsByYear W20028037062012 @default.
- W2002803706 countsByYear W20028037062014 @default.
- W2002803706 countsByYear W20028037062015 @default.
- W2002803706 countsByYear W20028037062021 @default.
- W2002803706 crossrefType "journal-article" @default.
- W2002803706 hasAuthorship W2002803706A5003344696 @default.
- W2002803706 hasAuthorship W2002803706A5056030840 @default.
- W2002803706 hasAuthorship W2002803706A5065414106 @default.
- W2002803706 hasAuthorship W2002803706A5088480770 @default.
- W2002803706 hasConcept C126322002 @default.
- W2002803706 hasConcept C134018914 @default.
- W2002803706 hasConcept C170493617 @default.
- W2002803706 hasConcept C185592680 @default.
- W2002803706 hasConcept C2776552330 @default.
- W2002803706 hasConcept C2779701627 @default.
- W2002803706 hasConcept C2780062018 @default.
- W2002803706 hasConcept C28406088 @default.
- W2002803706 hasConcept C50156730 @default.
- W2002803706 hasConcept C513476851 @default.
- W2002803706 hasConcept C515207424 @default.
- W2002803706 hasConcept C55493867 @default.
- W2002803706 hasConcept C61174792 @default.
- W2002803706 hasConcept C71924100 @default.
- W2002803706 hasConcept C86803240 @default.
- W2002803706 hasConceptScore W2002803706C126322002 @default.
- W2002803706 hasConceptScore W2002803706C134018914 @default.
- W2002803706 hasConceptScore W2002803706C170493617 @default.
- W2002803706 hasConceptScore W2002803706C185592680 @default.
- W2002803706 hasConceptScore W2002803706C2776552330 @default.
- W2002803706 hasConceptScore W2002803706C2779701627 @default.
- W2002803706 hasConceptScore W2002803706C2780062018 @default.
- W2002803706 hasConceptScore W2002803706C28406088 @default.