FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002828813> ?p ?o ?g. }

• W2002828813 endingPage "751" @default.
• W2002828813 startingPage "744" @default.
• W2002828813 abstract "<h3>Objective:</h3> To determine whether extracranial-intracranial (EC-IC) bypass can improve cognition over 2 years compared to best medical therapy alone in patients with symptomatic internal carotid artery (ICA) occlusion and increased oxygen extraction fraction (OEF) on PET. <h3>Methods:</h3> Patients underwent ¹⁵O PET and were randomized if OEF ratio was >1.13 on the occluded side. Using blinded baseline and 2-year cognitive assessments, age-adjusted composite <i>z</i> scores were generated from subtests sensitive to right/left hemisphere plus global cognitive functioning. Multiple regression predicted 2-year cognitive change. <h3>Results:</h3> Eighty-nine patients were enrolled; 41 had increased OEF and were randomized. Two died, 2 were lost to follow-up, and 2 refused 2-year testing. Of the 35 remaining, 6 had ipsilateral stroke or death, leaving 13 surgical and 16 medical patients. Controlling for age, education, and depression, there was no difference in 2-year cognitive change between the medical and surgical arms (95% confidence interval −0.5 to 0.5, <i>p</i> = 0.9). In post hoc analysis of 26 patients with no stroke in the follow-up period, cognitive improvement was associated with less impaired PET OEF at baseline (<i>p</i> = 0.045). <h3>Conclusion:</h3> Cognitive improvement following bypass surgery was not superior to medical therapy among patients with recently symptomatic carotid occlusion and increased OEF. Among those with no recurrent stroke, less hemodynamic impairment at baseline was associated with greater cognitive gain in both groups. Reversing cognitive impairment in hemodynamic failure remains an open challenge. <h3>Classification of evidence:</h3> This study provides Class II evidence that for patients with symptomatic ICA occlusion and increased OEF on PET, EC-IC bypass compared to no bypass does not improve cognitive function after 2 years." @default.
• W2002828813 created "2016-06-24" @default.
• W2002828813 creator A5014811020 @default.
• W2002828813 creator A5019594717 @default.
• W2002828813 creator A5057930855 @default.
• W2002828813 creator A5070057851 @default.
• W2002828813 creator A5071394210 @default.
• W2002828813 creator A5072272174 @default.
• W2002828813 creator A5075024081 @default.
• W2002828813 creator A5082318089 @default.
• W2002828813 creator A5088034421 @default.
• W2002828813 creator A5090893538 @default.
• W2002828813 creator A5091780509 @default.
• W2002828813 date "2014-01-29" @default.
• W2002828813 modified "2023-10-05" @default.
• W2002828813 title "Randomized Evaluation of Carotid Occlusion and Neurocognition (RECON) trial: Main results" @default.
• W2002828813 cites W1484864026 @default.
• W2002828813 cites W1485102983 @default.
• W2002828813 cites W1518238003 @default.
• W2002828813 cites W1522435878 @default.
• W2002828813 cites W1968246848 @default.
• W2002828813 cites W1972746391 @default.
• W2002828813 cites W1975505777 @default.
• W2002828813 cites W1982699469 @default.
• W2002828813 cites W1982778530 @default.
• W2002828813 cites W1987117423 @default.
• W2002828813 cites W2010818645 @default.
• W2002828813 cites W2011937112 @default.
• W2002828813 cites W2041917974 @default.
• W2002828813 cites W2043063769 @default.
• W2002828813 cites W2058291728 @default.
• W2002828813 cites W2062987239 @default.
• W2002828813 cites W2063555256 @default.
• W2002828813 cites W2076965707 @default.
• W2002828813 cites W2079965952 @default.
• W2002828813 cites W2088471890 @default.
• W2002828813 cites W2088758294 @default.
• W2002828813 cites W2099566728 @default.
• W2002828813 cites W2107031757 @default.
• W2002828813 cites W2110855618 @default.
• W2002828813 cites W2116087853 @default.
• W2002828813 cites W2128017604 @default.
• W2002828813 cites W2129870994 @default.
• W2002828813 cites W2143402957 @default.
• W2002828813 cites W2155775475 @default.
• W2002828813 cites W2159245100 @default.
• W2002828813 cites W2160093157 @default.
• W2002828813 cites W2162955241 @default.
• W2002828813 cites W2168673889 @default.
• W2002828813 cites W2325537322 @default.
• W2002828813 cites W2914361811 @default.
• W2002828813 cites W2125672808 @default.
• W2002828813 doi "https://doi.org/10.1212/wnl.0000000000000167" @default.
• W2002828813 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3945653" @default.
• W2002828813 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24477109" @default.
• W2002828813 hasPublicationYear "2014" @default.
• W2002828813 type Work @default.
• W2002828813 sameAs 2002828813 @default.
• W2002828813 citedByCount "64" @default.
• W2002828813 countsByYear W20028288132014 @default.
• W2002828813 countsByYear W20028288132015 @default.
• W2002828813 countsByYear W20028288132016 @default.
• W2002828813 countsByYear W20028288132017 @default.
• W2002828813 countsByYear W20028288132018 @default.
• W2002828813 countsByYear W20028288132019 @default.
• W2002828813 countsByYear W20028288132020 @default.
• W2002828813 countsByYear W20028288132021 @default.
• W2002828813 countsByYear W20028288132022 @default.
• W2002828813 countsByYear W20028288132023 @default.
• W2002828813 crossrefType "journal-article" @default.
• W2002828813 hasAuthorship W2002828813A5014811020 @default.
• W2002828813 hasAuthorship W2002828813A5019594717 @default.
• W2002828813 hasAuthorship W2002828813A5057930855 @default.
• W2002828813 hasAuthorship W2002828813A5070057851 @default.
• W2002828813 hasAuthorship W2002828813A5071394210 @default.
• W2002828813 hasAuthorship W2002828813A5072272174 @default.
• W2002828813 hasAuthorship W2002828813A5075024081 @default.
• W2002828813 hasAuthorship W2002828813A5082318089 @default.
• W2002828813 hasAuthorship W2002828813A5088034421 @default.
• W2002828813 hasAuthorship W2002828813A5090893538 @default.
• W2002828813 hasAuthorship W2002828813A5091780509 @default.
• W2002828813 hasBestOaLocation W20028288132 @default.
• W2002828813 hasConcept C118552586 @default.
• W2002828813 hasConcept C126322002 @default.
• W2002828813 hasConcept C127413603 @default.
• W2002828813 hasConcept C141071460 @default.
• W2002828813 hasConcept C164705383 @default.
• W2002828813 hasConcept C168563851 @default.
• W2002828813 hasConcept C169900460 @default.
• W2002828813 hasConcept C172467417 @default.
• W2002828813 hasConcept C185711340 @default.
• W2002828813 hasConcept C2776268601 @default.
• W2002828813 hasConcept C2779134260 @default.
• W2002828813 hasConcept C2779483572 @default.
• W2002828813 hasConcept C2780645631 @default.
• W2002828813 hasConcept C2984863031 @default.
• W2002828813 hasConcept C44249647 @default.
• W2002828813 hasConcept C71924100 @default.

• next