FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002897380> ?p ?o ?g. }

• W2002897380 endingPage "235" @default.
• W2002897380 startingPage "229" @default.
• W2002897380 abstract "Objectives The aim of the study was to identify and characterize hepatitis B virus (HBV) polymerase gene mutations associated with ongoing HBV replication in HIV/HBV‐coinfected individuals receiving tenofovir (TDF). Methods This retrospective cross‐sectional study identified 28 HIV/HBV‐coinfected individuals who had received TDF for at least 3 months. All patients had samples available while receiving TDF (on‐TDF), and 24 also had samples available prior to treatment (pre‐TDF). Case records were reviewed to obtain clinical and virological data at the times of sampling (±3 months). The HBV DNA of all samples was amplified using polymerase chain reaction (PCR), and the polymerase region of PCR‐positive samples was sequenced and compared with reference HBV data. Results Of the pre‐TDF samples, 15 of 24 (63%) were HBV PCR positive. Of the on‐TDF samples, four of 28 (14%) were HBV PCR positive (mean time on TDF 13.5 months; range 3–23 months). Lamivudine (3TC)‐resistance mutations were detected in three of four (75%) of these viraemic samples. The previously identified putative TDF‐resistance mutations, rtA194T+rtL180M+rtM204V, were not detected in any individual. Conclusions Unique mutations in the HBV polymerase gene associated with TDF resistance are rare in HIV/HBV coinfection. 3TC‐resistance mutations persist and a significant proportion of patients are HBV PCR positive despite the addition of TDF." @default.
• W2002897380 created "2016-06-24" @default.
• W2002897380 creator A5002122776 @default.
• W2002897380 creator A5010048599 @default.
• W2002897380 creator A5012792024 @default.
• W2002897380 creator A5032963402 @default.
• W2002897380 creator A5045422328 @default.
• W2002897380 creator A5053582876 @default.
• W2002897380 creator A5058294529 @default.
• W2002897380 creator A5062645957 @default.
• W2002897380 creator A5077979125 @default.
• W2002897380 creator A5085621586 @default.
• W2002897380 date "2009-03-11" @default.
• W2002897380 modified "2023-10-10" @default.
• W2002897380 title "Prolonged use of tenofovir in HIV/hepatitis B virus (HBV)-coinfected individuals does not lead to HBV polymerase mutations and is associated with persistence of lamivudine HBV polymerase mutations" @default.
• W2002897380 cites W1966772739 @default.
• W2002897380 cites W1973933851 @default.
• W2002897380 cites W1984816914 @default.
• W2002897380 cites W1985520044 @default.
• W2002897380 cites W1985577568 @default.
• W2002897380 cites W2007202675 @default.
• W2002897380 cites W2014097029 @default.
• W2002897380 cites W2014500655 @default.
• W2002897380 cites W2029914836 @default.
• W2002897380 cites W2046924643 @default.
• W2002897380 cites W2058379533 @default.
• W2002897380 cites W2070341160 @default.
• W2002897380 cites W2077844977 @default.
• W2002897380 cites W2089274167 @default.
• W2002897380 cites W2102523161 @default.
• W2002897380 cites W2110941134 @default.
• W2002897380 cites W2111704741 @default.
• W2002897380 cites W2114786837 @default.
• W2002897380 cites W2145899386 @default.
• W2002897380 cites W2152664737 @default.
• W2002897380 cites W2170164020 @default.
• W2002897380 cites W2317069692 @default.
• W2002897380 cites W2327827871 @default.
• W2002897380 cites W2431972701 @default.
• W2002897380 cites W56769326 @default.
• W2002897380 cites W72142418 @default.
• W2002897380 cites W93400950 @default.
• W2002897380 doi "https://doi.org/10.1111/j.1468-1293.2008.00675.x" @default.
• W2002897380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19178592" @default.
• W2002897380 hasPublicationYear "2009" @default.
• W2002897380 type Work @default.
• W2002897380 sameAs 2002897380 @default.
• W2002897380 citedByCount "33" @default.
• W2002897380 countsByYear W20028973802012 @default.
• W2002897380 countsByYear W20028973802014 @default.
• W2002897380 countsByYear W20028973802015 @default.
• W2002897380 countsByYear W20028973802016 @default.
• W2002897380 countsByYear W20028973802017 @default.
• W2002897380 countsByYear W20028973802018 @default.
• W2002897380 countsByYear W20028973802019 @default.
• W2002897380 countsByYear W20028973802020 @default.
• W2002897380 countsByYear W20028973802021 @default.
• W2002897380 crossrefType "journal-article" @default.
• W2002897380 hasAuthorship W2002897380A5002122776 @default.
• W2002897380 hasAuthorship W2002897380A5010048599 @default.
• W2002897380 hasAuthorship W2002897380A5012792024 @default.
• W2002897380 hasAuthorship W2002897380A5032963402 @default.
• W2002897380 hasAuthorship W2002897380A5045422328 @default.
• W2002897380 hasAuthorship W2002897380A5053582876 @default.
• W2002897380 hasAuthorship W2002897380A5058294529 @default.
• W2002897380 hasAuthorship W2002897380A5062645957 @default.
• W2002897380 hasAuthorship W2002897380A5077979125 @default.
• W2002897380 hasAuthorship W2002897380A5085621586 @default.
• W2002897380 hasBestOaLocation W20028973801 @default.
• W2002897380 hasConcept C104317684 @default.
• W2002897380 hasConcept C156719811 @default.
• W2002897380 hasConcept C159047783 @default.
• W2002897380 hasConcept C182707283 @default.
• W2002897380 hasConcept C2522874641 @default.
• W2002897380 hasConcept C2777382497 @default.
• W2002897380 hasConcept C2777813720 @default.
• W2002897380 hasConcept C2777869810 @default.
• W2002897380 hasConcept C2780593183 @default.
• W2002897380 hasConcept C49105822 @default.
• W2002897380 hasConcept C54355233 @default.
• W2002897380 hasConcept C71924100 @default.
• W2002897380 hasConcept C86803240 @default.
• W2002897380 hasConceptScore W2002897380C104317684 @default.
• W2002897380 hasConceptScore W2002897380C156719811 @default.
• W2002897380 hasConceptScore W2002897380C159047783 @default.
• W2002897380 hasConceptScore W2002897380C182707283 @default.
• W2002897380 hasConceptScore W2002897380C2522874641 @default.
• W2002897380 hasConceptScore W2002897380C2777382497 @default.
• W2002897380 hasConceptScore W2002897380C2777813720 @default.
• W2002897380 hasConceptScore W2002897380C2777869810 @default.
• W2002897380 hasConceptScore W2002897380C2780593183 @default.
• W2002897380 hasConceptScore W2002897380C49105822 @default.
• W2002897380 hasConceptScore W2002897380C54355233 @default.
• W2002897380 hasConceptScore W2002897380C71924100 @default.
• W2002897380 hasConceptScore W2002897380C86803240 @default.
• W2002897380 hasIssue "4" @default.
• W2002897380 hasLocation W20028973801 @default.
• W2002897380 hasLocation W20028973802 @default.

• next