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• W2002917494 abstract "Background Since pulmonary artery balloon flotation catheterization was first introduced in 1970, by HJ Swan and W Ganz, it has been widely disseminated as a diagnostic tool without rigorous evaluation of its clinical utility and effectiveness in critically ill patients. A pulmonary artery catheter (PAC) is inserted through a central venous access into the right side of the heart and floated into the pulmonary artery. PAC is used to measure stroke volume, cardiac output, mixed venous oxygen saturation and intracardiac pressures with a variety of additional calculated variables to guide diagnosis and treatment. Complications of the procedure are mainly related to line insertion. Relatively uncommon complications include cardiac arrhythmias, pulmonary haemorrhage and infarct, and associated mortality from balloon tip rupture. Objectives To provide an up‐to‐date assessment of the effectiveness of a PAC on mortality, length of stay (LOS) in intensive care unit (ICU) and hospital and cost of care in adult intensive care patients. Search methods We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 12); MEDLINE (1954 to January 2012); EMBASE (1980 to January 2012); CINAHL (1982 to January 2012), and reference lists of articles. We contacted researchers in the field. We did a grey literature search for articles published until January 2012. Selection criteria We included all randomized controlled trials conducted in adults ICUs, comparing management with and without a PAC. Data collection and analysis We screened the titles and abstracts and then the full text reports identified from our electronic search. Two authors (SR and MG) independently reviewed the titles, abstracts and then the full text reports for inclusion. We determined the final list of included studies by discussion among the group members (SR, ND, MG, AK and SC) with consensus agreement. We included all the studies that were in the original review. We assessed seven domains of potential risk of bias for the included studies. We examined the clinical, methodological and statistical heterogeneity and used random‐effects model for meta‐analysis. We calculated risk ratio for mortality across studies and mean days for LOS. Main results We included 13 studies (5686 patients). We judged blinding of participants and personnel and blinding of outcome assessment to be at high risk in about 50% of the included studies and at low risk in 25% to 30% of the studies. Regardless of the high risk of performance bias these studies were included based on the low weight the studies had in the meta‐analysis. We rated 75% of the studies as low risk for selection, attrition and reporting bias. All 13 studies reported some type of hospital mortality (28‐day, 30‐day, 60‐day or ICU mortality). We considered studies of high‐risk surgery patients (eight studies) and general intensive care patients (five studies) separately as subgroups for meta‐analysis. The pooled risk ratio (RR) for mortality for the studies of general intensive care patients was 1.02 (95% confidence interval (CI) 0.96 to 1.09) and for the studies of high‐risk surgery patients the RR was 0.98 (95% CI 0.74 to 1.29). Of the eight studies of high‐risk surgery patients, five evaluated the effectiveness of pre‐operative optimization but there was no difference in mortality when these studies were examined separately. PAC did not affect general ICU LOS (reported by four studies) or hospital LOS (reported by nine studies). Four studies, conducted in the United States (US), reported costs based on hospital charges billed, which on average were higher in the PAC groups. Two of these studies qualified for analysis and did not show a statistically significant hospital cost difference (mean difference USD 900, 95% CI ‐2620 to 4420, P = 0.62). Authors' conclusions PAC is a diagnostic and haemodynamic monitoring tool but not a therapeutic intervention. Our review concluded that use of a PAC did not alter the mortality, general ICU or hospital LOS, or cost for adult patients in intensive care. The quality of evidence was high for mortality and LOS but low for cost analysis. Efficacy studies are needed to determine if there are optimal PAC‐guided management protocols, which when applied to specific patient groups in ICUs could result in benefits such as shock reversal, improved organ function and less vasopressor use. Newer, less‐invasive haemodynamic monitoring tools need to be validated against PAC prior to clinical use in critically ill patients." @default.
• W2002917494 created "2016-06-24" @default.
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• W2002917494 date "2013-02-28" @default.
• W2002917494 modified "2023-10-17" @default.
• W2002917494 title "Pulmonary artery catheters for adult patients in intensive care" @default.
• W2002917494 cites W151537006 @default.
• W2002917494 cites W151864978 @default.
• W2002917494 cites W1536685404 @default.
• W2002917494 cites W1603297131 @default.
• W2002917494 cites W16401635 @default.
• W2002917494 cites W171219159 @default.
• W2002917494 cites W1901907981 @default.
• W2002917494 cites W1971267916 @default.
• W2002917494 cites W1972930194 @default.
• W2002917494 cites W1973505564 @default.
• W2002917494 cites W1975076387 @default.
• W2002917494 cites W1976326735 @default.
• W2002917494 cites W1979124371 @default.
• W2002917494 cites W1982531963 @default.
• W2002917494 cites W1984446100 @default.
• W2002917494 cites W1984766461 @default.
• W2002917494 cites W1988915849 @default.
• W2002917494 cites W1992542106 @default.
• W2002917494 cites W1994868010 @default.
• W2002917494 cites W1997108856 @default.
• W2002917494 cites W1998912187 @default.
• W2002917494 cites W1999253096 @default.
• W2002917494 cites W2002917494 @default.
• W2002917494 cites W2018308183 @default.
• W2002917494 cites W2030856114 @default.
• W2002917494 cites W2032646400 @default.
• W2002917494 cites W2035934946 @default.
• W2002917494 cites W2040355923 @default.
• W2002917494 cites W2042994363 @default.
• W2002917494 cites W2049251799 @default.
• W2002917494 cites W2056841035 @default.
• W2002917494 cites W2058586123 @default.
• W2002917494 cites W2059922567 @default.
• W2002917494 cites W2067384980 @default.
• W2002917494 cites W2069290964 @default.
• W2002917494 cites W2075606082 @default.
• W2002917494 cites W2077905695 @default.
• W2002917494 cites W2082082537 @default.
• W2002917494 cites W2083438506 @default.
• W2002917494 cites W2094111986 @default.
• W2002917494 cites W2094463755 @default.
• W2002917494 cites W2094620883 @default.
• W2002917494 cites W2096016693 @default.
• W2002917494 cites W2097095217 @default.
• W2002917494 cites W2097764726 @default.
• W2002917494 cites W2102460824 @default.
• W2002917494 cites W2115505194 @default.
• W2002917494 cites W2123286581 @default.
• W2002917494 cites W2128252369 @default.
• W2002917494 cites W2128565092 @default.
• W2002917494 cites W2135957123 @default.
• W2002917494 cites W2144587721 @default.
• W2002917494 cites W2149134020 @default.
• W2002917494 cites W2154390395 @default.
• W2002917494 cites W2156967952 @default.
• W2002917494 cites W2158216176 @default.
• W2002917494 cites W2158708148 @default.
• W2002917494 cites W2160691650 @default.
• W2002917494 cites W2162519017 @default.
• W2002917494 cites W2166724004 @default.
• W2002917494 cites W2169250915 @default.
• W2002917494 cites W2170312276 @default.
• W2002917494 cites W2171467831 @default.
• W2002917494 cites W2230520490 @default.
• W2002917494 cites W2299836127 @default.
• W2002917494 cites W2310294160 @default.
• W2002917494 cites W2317923971 @default.
• W2002917494 cites W2321299297 @default.
• W2002917494 cites W2326364273 @default.
• W2002917494 cites W2335979543 @default.
• W2002917494 cites W2395046680 @default.
• W2002917494 cites W2415301918 @default.
• W2002917494 cites W2415352609 @default.
• W2002917494 cites W2611511114 @default.
• W2002917494 cites W2779668584 @default.
• W2002917494 cites W3216534439 @default.
• W2002917494 cites W34268473 @default.
• W2002917494 cites W4236275177 @default.
• W2002917494 cites W4241719178 @default.
• W2002917494 cites W4323237193 @default.
• W2002917494 doi "https://doi.org/10.1002/14651858.cd003408.pub3" @default.
• W2002917494 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6517063" @default.
• W2002917494 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23450539" @default.
• W2002917494 hasPublicationYear "2013" @default.
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