FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002940212> ?p ?o ?g. }

• W2002940212 endingPage "p94" @default.
• W2002940212 startingPage "p87" @default.
• W2002940212 abstract "Na⁺-HCO₃^– cotransporter (NBC1) plays a major role in bicarbonate reabsorption from proximal tubules. In a previous immunohistochemical study on human kidney, we showed that the kidney-type transporter (kNBC1) was abundantly expressed in the basolateral membranes of proximal tubules while the expression of pancreatic-type transporter (pNBC1) was undetectable. In the present study we tried to determine the localization of NBC1 variants in rat kidney using the antibodies against the unique N-terminal regions of kNBC1 and pNBC1. In Western blot analysis on the membrane-enriched fraction from rat kidney both anti-kNBC1 and anti-pNBC1 antibodies yielded a ∼130 kDa band. In immunohistochemical analysis with confocal microscopy the anti-kNBC1 antibody produced a strong and exclusively basolateral labeling in proximal tubules. On the other hand, the occasional pNBC1 labeling was detected in the apical membranes of proximal tubules. The electron microscopic observation further supported the basolateral localization of kNBC1 as well as the localization of pNBC1 on the basis of the brush border. Acute metabolic acidosis did not change the protein expression levels as well as the intracellular distribution of both NBC1 variants in rat kidney. These results are consistent with a view that kNBC1 is the dominant variant that mediates bicarbonate reabsorption from rat renal proximal tubules. They also indicate that species difference may exist regarding the distribution of NBC1 variants in kidney." @default.
• W2002940212 created "2016-06-24" @default.
• W2002940212 creator A5015944502 @default.
• W2002940212 creator A5024081838 @default.
• W2002940212 creator A5031040915 @default.
• W2002940212 creator A5049398456 @default.
• W2002940212 creator A5060662946 @default.
• W2002940212 creator A5069026090 @default.
• W2002940212 creator A5070873839 @default.
• W2002940212 creator A5076351619 @default.
• W2002940212 creator A5076829080 @default.
• W2002940212 creator A5079596786 @default.
• W2002940212 creator A5080266991 @default.
• W2002940212 creator A5088142557 @default.
• W2002940212 date "2006-09-28" @default.
• W2002940212 modified "2023-10-18" @default.
• W2002940212 title "Localization of NBC1 Variants in Rat Kidney" @default.
• W2002940212 cites W1589657989 @default.
• W2002940212 cites W1937078385 @default.
• W2002940212 cites W1979369057 @default.
• W2002940212 cites W1980331103 @default.
• W2002940212 cites W1982833218 @default.
• W2002940212 cites W1988610091 @default.
• W2002940212 cites W2007549664 @default.
• W2002940212 cites W2013788937 @default.
• W2002940212 cites W2029209604 @default.
• W2002940212 cites W2031847928 @default.
• W2002940212 cites W2036533527 @default.
• W2002940212 cites W2043072882 @default.
• W2002940212 cites W2048812621 @default.
• W2002940212 cites W2053137524 @default.
• W2002940212 cites W2061133484 @default.
• W2002940212 cites W2062805140 @default.
• W2002940212 cites W2079853661 @default.
• W2002940212 cites W2080882597 @default.
• W2002940212 cites W2086915337 @default.
• W2002940212 cites W2091025692 @default.
• W2002940212 cites W2097456656 @default.
• W2002940212 cites W2116938316 @default.
• W2002940212 cites W2118527116 @default.
• W2002940212 cites W2120196934 @default.
• W2002940212 cites W2121193330 @default.
• W2002940212 cites W2122399252 @default.
• W2002940212 cites W2126323646 @default.
• W2002940212 cites W2140592163 @default.
• W2002940212 cites W2147908804 @default.
• W2002940212 cites W2155129970 @default.
• W2002940212 cites W2165635424 @default.
• W2002940212 cites W2185851266 @default.
• W2002940212 cites W2186634945 @default.
• W2002940212 cites W2190923783 @default.
• W2002940212 cites W2256328177 @default.
• W2002940212 cites W2394580393 @default.
• W2002940212 cites W2407627493 @default.
• W2002940212 cites W2885443459 @default.
• W2002940212 doi "https://doi.org/10.1159/000094003" @default.
• W2002940212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16785749" @default.
• W2002940212 hasPublicationYear "2006" @default.
• W2002940212 type Work @default.
• W2002940212 sameAs 2002940212 @default.
• W2002940212 citedByCount "15" @default.
• W2002940212 countsByYear W20029402122013 @default.
• W2002940212 countsByYear W20029402122016 @default.
• W2002940212 countsByYear W20029402122018 @default.
• W2002940212 countsByYear W20029402122019 @default.
• W2002940212 countsByYear W20029402122020 @default.
• W2002940212 countsByYear W20029402122022 @default.
• W2002940212 countsByYear W20029402122023 @default.
• W2002940212 crossrefType "journal-article" @default.
• W2002940212 hasAuthorship W2002940212A5015944502 @default.
• W2002940212 hasAuthorship W2002940212A5024081838 @default.
• W2002940212 hasAuthorship W2002940212A5031040915 @default.
• W2002940212 hasAuthorship W2002940212A5049398456 @default.
• W2002940212 hasAuthorship W2002940212A5060662946 @default.
• W2002940212 hasAuthorship W2002940212A5069026090 @default.
• W2002940212 hasAuthorship W2002940212A5070873839 @default.
• W2002940212 hasAuthorship W2002940212A5076351619 @default.
• W2002940212 hasAuthorship W2002940212A5076829080 @default.
• W2002940212 hasAuthorship W2002940212A5079596786 @default.
• W2002940212 hasAuthorship W2002940212A5080266991 @default.
• W2002940212 hasAuthorship W2002940212A5088142557 @default.
• W2002940212 hasConcept C104317684 @default.
• W2002940212 hasConcept C126322002 @default.
• W2002940212 hasConcept C130316041 @default.
• W2002940212 hasConcept C134018914 @default.
• W2002940212 hasConcept C142724271 @default.
• W2002940212 hasConcept C153911025 @default.
• W2002940212 hasConcept C178790620 @default.
• W2002940212 hasConcept C185592680 @default.
• W2002940212 hasConcept C188053792 @default.
• W2002940212 hasConcept C2776415932 @default.
• W2002940212 hasConcept C2779010597 @default.
• W2002940212 hasConcept C2780091579 @default.
• W2002940212 hasConcept C3018436504 @default.
• W2002940212 hasConcept C39587587 @default.
• W2002940212 hasConcept C41625074 @default.
• W2002940212 hasConcept C529295009 @default.
• W2002940212 hasConcept C537181965 @default.

• next