FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002951090> ?p ?o ?g. }

• W2002951090 abstract "Abstract Satellite phage P4 multiplies only in the presence of its helper P2 and requires each morphogenesis function of P2 for phage maturation. The helper phage P2 can be present either as prophage or as a co-infecting phage. We have isolated mutant P2 lysogens unable to support P4 growth. These carry mutations lying in the region of P2 early genes. Measurement of P2 lysozyme synthesis indicates that in these mutants, P2 late genes are activated inefficiently during P4 infection. Complementation tests show that the P4 stimulation function, which is absent in the defective lysogens, can be provided in trans by another prophage. This function cannot be assigned to either of the two known early genes of P2 which are required for late gene transcription during P2 vegetative growth; P4 multiplies normally when both P2 early genes A and B are inactivated by amber mutations. A dominant mutation of P2 has been isolated which makes repressed P2 incapable of supporting P4 multiplication. The mutation prevents derepression of the P2 prophage and may alter the P2 repressor. We propose that two different pathways exist for activation of P2 late genes: (1) a pathway dependent on P2 replication and (2) a pathway activated by satellite P4. One component of the P4-dependent pathway is a diffusible P2 early gene function under the control of P2 repressor. This function acts to stimulate the P2 late gene transcription in the P4-dependent pathway." @default.
• W2002951090 created "2016-06-24" @default.
• W2002951090 creator A5004591915 @default.
• W2002951090 creator A5066873279 @default.
• W2002951090 date "1978-12-01" @default.
• W2002951090 modified "2023-10-17" @default.
• W2002951090 title "Mutations of bacteriophage P2 which prevent activation of P2 late genes by satellite phage P4" @default.
• W2002951090 cites W136365200 @default.
• W2002951090 cites W14128489 @default.
• W2002951090 cites W1546783991 @default.
• W2002951090 cites W1943327251 @default.
• W2002951090 cites W1964101654 @default.
• W2002951090 cites W1964750385 @default.
• W2002951090 cites W1975101332 @default.
• W2002951090 cites W1977601174 @default.
• W2002951090 cites W1978662360 @default.
• W2002951090 cites W1980002594 @default.
• W2002951090 cites W1994571306 @default.
• W2002951090 cites W1995180297 @default.
• W2002951090 cites W1995961753 @default.
• W2002951090 cites W1999258947 @default.
• W2002951090 cites W2000738758 @default.
• W2002951090 cites W2002742850 @default.
• W2002951090 cites W2010708494 @default.
• W2002951090 cites W2015237046 @default.
• W2002951090 cites W2017034082 @default.
• W2002951090 cites W2021453367 @default.
• W2002951090 cites W2030098014 @default.
• W2002951090 cites W2030627788 @default.
• W2002951090 cites W2038115958 @default.
• W2002951090 cites W2041711910 @default.
• W2002951090 cites W2043439371 @default.
• W2002951090 cites W2054011998 @default.
• W2002951090 cites W2063673782 @default.
• W2002951090 cites W2066899729 @default.
• W2002951090 cites W2067239835 @default.
• W2002951090 cites W2069251340 @default.
• W2002951090 cites W2070250918 @default.
• W2002951090 cites W2077749225 @default.
• W2002951090 cites W2080305943 @default.
• W2002951090 cites W2081802559 @default.
• W2002951090 cites W2093810516 @default.
• W2002951090 cites W2095506983 @default.
• W2002951090 cites W2128814709 @default.
• W2002951090 cites W2154842323 @default.
• W2002951090 cites W94650790 @default.
• W2002951090 doi "https://doi.org/10.1016/0042-6822(78)90380-x" @default.
• W2002951090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/741656" @default.
• W2002951090 hasPublicationYear "1978" @default.
• W2002951090 type Work @default.
• W2002951090 sameAs 2002951090 @default.
• W2002951090 citedByCount "8" @default.
• W2002951090 countsByYear W20029510902015 @default.
• W2002951090 crossrefType "journal-article" @default.
• W2002951090 hasAuthorship W2002951090A5004591915 @default.
• W2002951090 hasAuthorship W2002951090A5066873279 @default.
• W2002951090 hasConcept C104317684 @default.
• W2002951090 hasConcept C136199206 @default.
• W2002951090 hasConcept C138885662 @default.
• W2002951090 hasConcept C143065580 @default.
• W2002951090 hasConcept C150194340 @default.
• W2002951090 hasConcept C158448853 @default.
• W2002951090 hasConcept C179926584 @default.
• W2002951090 hasConcept C186310378 @default.
• W2002951090 hasConcept C188082640 @default.
• W2002951090 hasConcept C2776441376 @default.
• W2002951090 hasConcept C41895202 @default.
• W2002951090 hasConcept C48292096 @default.
• W2002951090 hasConcept C54355233 @default.
• W2002951090 hasConcept C547475151 @default.
• W2002951090 hasConcept C73445445 @default.
• W2002951090 hasConcept C73766848 @default.
• W2002951090 hasConcept C86339819 @default.
• W2002951090 hasConcept C86803240 @default.
• W2002951090 hasConceptScore W2002951090C104317684 @default.
• W2002951090 hasConceptScore W2002951090C136199206 @default.
• W2002951090 hasConceptScore W2002951090C138885662 @default.
• W2002951090 hasConceptScore W2002951090C143065580 @default.
• W2002951090 hasConceptScore W2002951090C150194340 @default.
• W2002951090 hasConceptScore W2002951090C158448853 @default.
• W2002951090 hasConceptScore W2002951090C179926584 @default.
• W2002951090 hasConceptScore W2002951090C186310378 @default.
• W2002951090 hasConceptScore W2002951090C188082640 @default.
• W2002951090 hasConceptScore W2002951090C2776441376 @default.
• W2002951090 hasConceptScore W2002951090C41895202 @default.
• W2002951090 hasConceptScore W2002951090C48292096 @default.
• W2002951090 hasConceptScore W2002951090C54355233 @default.
• W2002951090 hasConceptScore W2002951090C547475151 @default.
• W2002951090 hasConceptScore W2002951090C73445445 @default.
• W2002951090 hasConceptScore W2002951090C73766848 @default.
• W2002951090 hasConceptScore W2002951090C86339819 @default.
• W2002951090 hasConceptScore W2002951090C86803240 @default.
• W2002951090 hasLocation W20029510901 @default.
• W2002951090 hasLocation W20029510902 @default.
• W2002951090 hasOpenAccess W2002951090 @default.
• W2002951090 hasPrimaryLocation W20029510901 @default.
• W2002951090 hasRelatedWork W1562693820 @default.
• W2002951090 hasRelatedWork W1895018249 @default.
• W2002951090 hasRelatedWork W1984225124 @default.
• W2002951090 hasRelatedWork W2002595078 @default.

• next