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• W2002959145 abstract "Cancer cells undergo reprogramming of glucose metabolism to limit energy production to glycolysis-a state known as aerobic glycolysis. Hypoxia-inducible factor 1 (HIF1α) is a transcription factor that regulates many genes responsible for this switch. As discussed here, new data suggest that the tumor suppressor WW domain-containing oxidoreductase (WWOX) modulates HIF1α, thereby regulating this metabolic state." @default.
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• W2002959145 date "2014-10-30" @default.
• W2002959145 modified "2023-10-16" @default.
• W2002959145 title "WWOX loss activates aerobic glycolysis" @default.
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• W2002959145 doi "https://doi.org/10.4161/23723548.2014.965640" @default.
• W2002959145 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4904998" @default.
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