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- W2002972877 abstract "Aims: To examine the impact of research design on results in two published comparative effectiveness studies. Methods: Guidelines for comparative effectiveness research have recommended incorporating disease process in study design. Based on the recommendations, we develop a checklist of considerations and apply the checklist in review of two published studies on comparative effectiveness of colony-stimulating factors. Both studies used similar administrative claims data, but different methods, which resulted in directionally different estimates. Results: Major design differences between the two studies include: whether the timing of intervention in disease process was identified and whether study cohort and outcome assessment period were defined based on this temporal relationship. Conclusion: Disease process and timing of intervention should be incorporated into the design of comparative effectiveness studies." @default.
- W2002972877 created "2016-06-24" @default.
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- W2002972877 date "2015-01-01" @default.
- W2002972877 modified "2023-10-17" @default.
- W2002972877 title "Comparative effectiveness of colony-stimulating factors in febrile neutropenia prophylaxis: how results are affected by research design" @default.
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- W2002972877 doi "https://doi.org/10.2217/cer.14.62" @default.
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- W2002972877 hasPublicationYear "2015" @default.
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