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- W2002992032 abstract "Dihydroindenoisoquinolines are analogs of cytotoxic indenoisoquinoline topoisomerase I (Top1) inhibitors, exhibiting potent cytotoxicity but weak inhibitory activity toward Top1. Through COMPARE analysis, cytotoxicity studies in Top1-deficient cells, chemical synthesis and biological evaluation of methylated dihydroindenoisoquinoline 5, we demonstrated that dihydroindenoisoquinolines function as prodrugs of indenoisoquinolines in cancer cells." @default.
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- W2002992032 date "2005-06-01" @default.
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- W2002992032 title "Dihydroindenoisoquinolines function as prodrugs of indenoisoquinolines" @default.
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- W2002992032 doi "https://doi.org/10.1016/j.bmcl.2005.03.101" @default.
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