FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003010448> ?p ?o ?g. }

• W2003010448 endingPage "234" @default.
• W2003010448 startingPage "227" @default.
• W2003010448 abstract "Several viruses, including Orthomyxovirus, utilize cellular reactive oxygen species (ROS) for viral genomic replication and survival within host cells. However, the role of ROS in early events of viral entry and signal induction has not been elucidated. Here, we show that ISA virus (ISAV) induces ROS production very early during infection of CHSE-214 and SHK-1Ycells, and that production is sustained over the observed 24 h post-infection. The mitogen-activated protein kinase (MAPK) family is responsible for important signaling pathways. In this study, we report that ISAV activates ERK and p38 in Salmo salar. In salmonid macrophages, while ERK was required for SOD, GLURED, p47phox expression, p38 regulated the ROS production by the NADPH oxidase complex activation. These results, together with the presence of several consensus target motifs for p38 MAPK in the promoter of the S. salar p47phox gene, suggest that p38 MAPK regulates p47phox gene expression in fish through the activation of this key transcription factor." @default.
• W2003010448 created "2016-06-24" @default.
• W2003010448 creator A5007801787 @default.
• W2003010448 creator A5017697237 @default.
• W2003010448 creator A5024219930 @default.
• W2003010448 creator A5026900983 @default.
• W2003010448 creator A5035240392 @default.
• W2003010448 creator A5037750663 @default.
• W2003010448 creator A5055672571 @default.
• W2003010448 creator A5063612666 @default.
• W2003010448 date "2015-02-01" @default.
• W2003010448 modified "2023-09-27" @default.
• W2003010448 title "ISA virus regulates the generation of reactive oxygen species and p47phox expression in a p38 MAPK-dependent manner in Salmo salar" @default.
• W2003010448 cites W1483334228 @default.
• W2003010448 cites W1507143241 @default.
• W2003010448 cites W1968750053 @default.
• W2003010448 cites W1976286904 @default.
• W2003010448 cites W1978071486 @default.
• W2003010448 cites W1979225590 @default.
• W2003010448 cites W2001056362 @default.
• W2003010448 cites W2003305424 @default.
• W2003010448 cites W2008370957 @default.
• W2003010448 cites W2009063566 @default.
• W2003010448 cites W2035304200 @default.
• W2003010448 cites W2039286078 @default.
• W2003010448 cites W2040116000 @default.
• W2003010448 cites W2040609093 @default.
• W2003010448 cites W2046578982 @default.
• W2003010448 cites W2047236990 @default.
• W2003010448 cites W2065152876 @default.
• W2003010448 cites W2069280423 @default.
• W2003010448 cites W2075156841 @default.
• W2003010448 cites W2085128107 @default.
• W2003010448 cites W2090524722 @default.
• W2003010448 cites W2094552416 @default.
• W2003010448 cites W2102766596 @default.
• W2003010448 cites W2107932866 @default.
• W2003010448 cites W2111756793 @default.
• W2003010448 cites W2114417620 @default.
• W2003010448 cites W2118814154 @default.
• W2003010448 cites W2134030137 @default.
• W2003010448 cites W2153138756 @default.
• W2003010448 cites W2156613610 @default.
• W2003010448 cites W2163337744 @default.
• W2003010448 cites W2165201727 @default.
• W2003010448 cites W2168435069 @default.
• W2003010448 doi "https://doi.org/10.1016/j.molimm.2014.07.016" @default.
• W2003010448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25124144" @default.
• W2003010448 hasPublicationYear "2015" @default.
• W2003010448 type Work @default.
• W2003010448 sameAs 2003010448 @default.
• W2003010448 citedByCount "11" @default.
• W2003010448 countsByYear W20030104482015 @default.
• W2003010448 countsByYear W20030104482016 @default.
• W2003010448 countsByYear W20030104482019 @default.
• W2003010448 countsByYear W20030104482020 @default.
• W2003010448 countsByYear W20030104482021 @default.
• W2003010448 countsByYear W20030104482022 @default.
• W2003010448 countsByYear W20030104482023 @default.
• W2003010448 crossrefType "journal-article" @default.
• W2003010448 hasAuthorship W2003010448A5007801787 @default.
• W2003010448 hasAuthorship W2003010448A5017697237 @default.
• W2003010448 hasAuthorship W2003010448A5024219930 @default.
• W2003010448 hasAuthorship W2003010448A5026900983 @default.
• W2003010448 hasAuthorship W2003010448A5035240392 @default.
• W2003010448 hasAuthorship W2003010448A5037750663 @default.
• W2003010448 hasAuthorship W2003010448A5055672571 @default.
• W2003010448 hasAuthorship W2003010448A5063612666 @default.
• W2003010448 hasConcept C104317684 @default.
• W2003010448 hasConcept C153911025 @default.
• W2003010448 hasConcept C184235292 @default.
• W2003010448 hasConcept C2779719074 @default.
• W2003010448 hasConcept C48349386 @default.
• W2003010448 hasConcept C51551487 @default.
• W2003010448 hasConcept C54355233 @default.
• W2003010448 hasConcept C57074206 @default.
• W2003010448 hasConcept C86339819 @default.
• W2003010448 hasConcept C86803240 @default.
• W2003010448 hasConcept C95444343 @default.
• W2003010448 hasConceptScore W2003010448C104317684 @default.
• W2003010448 hasConceptScore W2003010448C153911025 @default.
• W2003010448 hasConceptScore W2003010448C184235292 @default.
• W2003010448 hasConceptScore W2003010448C2779719074 @default.
• W2003010448 hasConceptScore W2003010448C48349386 @default.
• W2003010448 hasConceptScore W2003010448C51551487 @default.
• W2003010448 hasConceptScore W2003010448C54355233 @default.
• W2003010448 hasConceptScore W2003010448C57074206 @default.
• W2003010448 hasConceptScore W2003010448C86339819 @default.
• W2003010448 hasConceptScore W2003010448C86803240 @default.
• W2003010448 hasConceptScore W2003010448C95444343 @default.
• W2003010448 hasIssue "2" @default.
• W2003010448 hasLocation W20030104481 @default.
• W2003010448 hasLocation W20030104482 @default.
• W2003010448 hasOpenAccess W2003010448 @default.
• W2003010448 hasPrimaryLocation W20030104481 @default.
• W2003010448 hasRelatedWork W1964986946 @default.
• W2003010448 hasRelatedWork W2004726042 @default.
• W2003010448 hasRelatedWork W2041626380 @default.

• next