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- W2003016053 abstract "The primary nucleotide sequence was reported earlier for U1 RNA (Reddy et al, (1974) J. Biol. Chem. 249, 6486–6494), an snRNA implicated in splicing of HnRNAs. In view of the presence of homologous pseudouridine (ψ) residues in 5′-ends of several highly conserved U-snRNAs and the recent report of modified bases in the U1 RNA structure (Branlant et al, (1980) Nucleic Acids Res. 8, 4143–4154) a study was made for the presence of ψ and other modified nucleotides in the 5′-end of the U1 RNA. Identification of ψ residues at positions 6 and 7, shows the 5′-sequence of U1 RNA is: m32, 2,7 GpppAm-Um-A-C-ψ-ψ-A-C-C-U-G-G-C-A-G-G-G-G-A-G-A-U-A-C. The ψ residues in place of U at positions 6 and 7 may affect the binding of U1 RNA at intron-exon splice junctions." @default.
- W2003016053 created "2016-06-24" @default.
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- W2003016053 date "1981-02-01" @default.
- W2003016053 modified "2023-09-27" @default.
- W2003016053 title "Pseudouridine residues in the 5′-terminus of uridine-rich nuclear RNA I (U1 RNA)" @default.
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- W2003016053 doi "https://doi.org/10.1016/0006-291x(81)91221-3" @default.
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