Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003026610> ?p ?o ?g. }
- W2003026610 endingPage "118" @default.
- W2003026610 startingPage "112" @default.
- W2003026610 abstract "Nitric oxide (NO) is formed as a consequence of induction of the iNOS enzyme during inflammatory disorders. To investigate NO production in multiple sclerosis (MS), we determined the concentrations of its oxidation products (NOx) in the cerebrospinal fluid (CSF) and plasma of 61 MS patients. The patients were divided into three groups on the basis of their clinical disease activity. The total levels of NOx in CSF were significantly increased in all MS groups as compared to healthy controls and tension headache patients. CSF nitrite correlated with clinical disease activity. At exacerbation, the CSF nitrite levels exceed the plasma level. This suggests that clinical disease activity is due to a CNS inflammatory response, which is more intense and qualitatively different from that during clinical stable phases. This study supports NO involvement in the pathogenesis of MS and determination of nitrite levels may be useful a surrogate marker for disease activity." @default.
- W2003026610 created "2016-06-24" @default.
- W2003026610 creator A5004587560 @default.
- W2003026610 creator A5015275115 @default.
- W2003026610 creator A5016015447 @default.
- W2003026610 creator A5032636253 @default.
- W2003026610 creator A5049453110 @default.
- W2003026610 creator A5086796270 @default.
- W2003026610 date "2003-03-01" @default.
- W2003026610 modified "2023-10-13" @default.
- W2003026610 title "Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis" @default.
- W2003026610 cites W1547957565 @default.
- W2003026610 cites W1753183749 @default.
- W2003026610 cites W1805879606 @default.
- W2003026610 cites W1937650001 @default.
- W2003026610 cites W1969396543 @default.
- W2003026610 cites W1973535328 @default.
- W2003026610 cites W1979230311 @default.
- W2003026610 cites W1980462938 @default.
- W2003026610 cites W1992727245 @default.
- W2003026610 cites W1998104086 @default.
- W2003026610 cites W2007737411 @default.
- W2003026610 cites W2011769338 @default.
- W2003026610 cites W2014797476 @default.
- W2003026610 cites W2015295078 @default.
- W2003026610 cites W2016640681 @default.
- W2003026610 cites W2031254657 @default.
- W2003026610 cites W2032872089 @default.
- W2003026610 cites W2033379487 @default.
- W2003026610 cites W2041052826 @default.
- W2003026610 cites W2046508329 @default.
- W2003026610 cites W2046652693 @default.
- W2003026610 cites W2049112657 @default.
- W2003026610 cites W2050167836 @default.
- W2003026610 cites W2051329971 @default.
- W2003026610 cites W2054939193 @default.
- W2003026610 cites W2056958245 @default.
- W2003026610 cites W2057662702 @default.
- W2003026610 cites W2062384458 @default.
- W2003026610 cites W2062454209 @default.
- W2003026610 cites W2063789732 @default.
- W2003026610 cites W2065287046 @default.
- W2003026610 cites W2065665699 @default.
- W2003026610 cites W2071542476 @default.
- W2003026610 cites W2073132923 @default.
- W2003026610 cites W2079982783 @default.
- W2003026610 cites W2080337955 @default.
- W2003026610 cites W2087589796 @default.
- W2003026610 cites W2102418949 @default.
- W2003026610 cites W2105294414 @default.
- W2003026610 cites W2120590429 @default.
- W2003026610 cites W2121723833 @default.
- W2003026610 cites W2123444403 @default.
- W2003026610 cites W2130355701 @default.
- W2003026610 cites W2134133368 @default.
- W2003026610 cites W2135271960 @default.
- W2003026610 cites W2147156322 @default.
- W2003026610 cites W2154416680 @default.
- W2003026610 cites W2168726651 @default.
- W2003026610 cites W2325735106 @default.
- W2003026610 cites W2345382232 @default.
- W2003026610 cites W4240195352 @default.
- W2003026610 cites W4254095336 @default.
- W2003026610 doi "https://doi.org/10.1016/s0165-5728(02)00464-2" @default.
- W2003026610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12620649" @default.
- W2003026610 hasPublicationYear "2003" @default.
- W2003026610 type Work @default.
- W2003026610 sameAs 2003026610 @default.
- W2003026610 citedByCount "97" @default.
- W2003026610 countsByYear W20030266102012 @default.
- W2003026610 countsByYear W20030266102013 @default.
- W2003026610 countsByYear W20030266102014 @default.
- W2003026610 countsByYear W20030266102015 @default.
- W2003026610 countsByYear W20030266102016 @default.
- W2003026610 countsByYear W20030266102017 @default.
- W2003026610 countsByYear W20030266102018 @default.
- W2003026610 countsByYear W20030266102019 @default.
- W2003026610 countsByYear W20030266102020 @default.
- W2003026610 countsByYear W20030266102021 @default.
- W2003026610 countsByYear W20030266102022 @default.
- W2003026610 countsByYear W20030266102023 @default.
- W2003026610 crossrefType "journal-article" @default.
- W2003026610 hasAuthorship W2003026610A5004587560 @default.
- W2003026610 hasAuthorship W2003026610A5015275115 @default.
- W2003026610 hasAuthorship W2003026610A5016015447 @default.
- W2003026610 hasAuthorship W2003026610A5032636253 @default.
- W2003026610 hasAuthorship W2003026610A5049453110 @default.
- W2003026610 hasAuthorship W2003026610A5086796270 @default.
- W2003026610 hasConcept C126322002 @default.
- W2003026610 hasConcept C178790620 @default.
- W2003026610 hasConcept C185592680 @default.
- W2003026610 hasConcept C203014093 @default.
- W2003026610 hasConcept C2776179834 @default.
- W2003026610 hasConcept C2776384668 @default.
- W2003026610 hasConcept C2776914184 @default.
- W2003026610 hasConcept C2777014857 @default.
- W2003026610 hasConcept C2777477808 @default.
- W2003026610 hasConcept C2779134260 @default.