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- W2003036174 abstract "Hycanthone inhibits macromolecular synthesis in L1210 cells. At the same concentrations of hycanthone, DNA synthesis is inhibited to a greater extent than the synthesis of RNA. There is an inhibition by the drug of the synthesis of ribosomal precursor RNA; the synthesis of other types of RNA including heterogeneous and small-molecular-weight, also appears to be inhibited. Maturation of 45-S RNA does not seem to be affected, and there is a partial reversal of inhibition of both DNA and RNA synthesis by washing the cells free of hycanthone." @default.
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- W2003036174 date "1975-01-01" @default.
- W2003036174 modified "2023-10-09" @default.
- W2003036174 title "Inhibition of macromolecular synthesis in L1210 mouse leukemia ascites cells by hycanthone" @default.
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- W2003036174 doi "https://doi.org/10.1016/0005-2787(75)90114-8" @default.
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