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• W2003046608 abstract "Abstract A rigid carbocyclic scaffold comprising of an all- cis 4,5-dihydroxy-1,3-cyclopentanedicarboxylic acid is developed. Attachment of peptide strands to the carboxylic groups of this novel template led to the peptidomimetics 2 and 3 . Conformational analysis by circular dichroism and NMR studies revealed that these molecules adopt a unique folded structure in nonpolar solvent involving intramolecular hydrogen bonding between PheNH of one strand and LeuCO (in 2 ) or GlyCO (in 3 ) of the other strand. This structure is very different from the structures observed earlier in their sugar counterparts ( 1 ). The paper describes in detail the synthesis and structural studies of compounds 2 and 3 ." @default.
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• W2003046608 date "2001-10-01" @default.
• W2003046608 modified "2023-09-27" @default.
• W2003046608 title "Synthesis and conformational studies of peptidomimetics containing a carbocyclic 1,3-diacid" @default.
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• W2003046608 doi "https://doi.org/10.1016/s0040-4020(01)00921-8" @default.
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