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• W2003054141 abstract "Oxidized-low-density lipoprotein (ox-LDL), which is generated by LDL oxidation, is a risk factor of cardiovascular disease development. LDL has positive charges on the surface attributable to amino groups of lysine moieties on Apo B-100. Its positive charge is decreased by oxidation. For this paper, the topography and surface potential of LDL and ox-LDL are measured using atomic force microscopy and Kelvin probe force microscopy (KPFM). Although it is difficult to ascertain a difference between topographic images of LDL and ox-LDL, the KPFM images of ox-LDL differ from those obtained using LDL. The averaged potential of the surface decreases concomitantly with increasing oxidation time of the LDL. We demonstrate a method to evaluate the oxidation level of LDL using KPFM." @default.
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• W2003054141 date "2013-09-01" @default.
• W2003054141 modified "2023-09-23" @default.
• W2003054141 title "Evaluation of Oxidized-Low-Density Lipoproteins Using Kelvin Force Microscopy" @default.
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• W2003054141 doi "https://doi.org/10.1109/jsen.2013.2265014" @default.
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