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• W2003058862 abstract "Tumour necrosis factor-&#945; (TNF-&#945;) was measured by enzyme-linked immunosorbent assay and eosinophil cationic protein (ECP) by radio-immunoassay to evaluate TNF-&#945; in nasal allergy. There was no significant difference either between the mean concentrations of TNF-&#945; in nasal secretions from the patients with perennial nasal allergy and those of normal subjects, or between the TNF-&#945; and ECP concentrations. However, reverse transcription polymerase chain reaction showed a specific increase of TNF-&#945; mRNA and IFN-&#947; mRNA in allergic nasal mucosa after allergen challenge <em>in vitro</em>. These findings suggest a possibility that T cell-derived IFN-&#947; up-regulates macrophages to elaborate TNF-&#945;, which may play a role in amplifying allergic inflammation in the nose through the cytokine network." @default.
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• W2003058862 date "1995-01-01" @default.
• W2003058862 modified "2023-09-26" @default.
• W2003058862 title "Tumour necrosis factor-α in nasal allergy" @default.
• W2003058862 doi "https://doi.org/10.1155/s0962935195000603" @default.
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