Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003080690> ?p ?o ?g. }
- W2003080690 endingPage "364" @default.
- W2003080690 startingPage "359" @default.
- W2003080690 abstract "The purpose of this study was to review the clinical course of patients diagnosed with vulvar melanoma. Charts of patients diagnosed between 1970 and 1997 were reviewed for demographics, lesion characteristics, disease duration and extent, and treatments. Actuarial survival curves were computed by the Kaplan Meier method and compared by Cox proportional hazards regressions. Fifty-one patients (median age 54) with vulvar melanoma presented with a vulvar mass (39%), pain (30%), bleeding (24%), and itching (20%). Anatomical distribution was mucosa of the vulva (65%), vulvar epidermal site (21%), or unspecified vulva (14%), with 20% having multifocal disease at diagnosis. Histologic types were superficial spreading or nodular (50% each). Median lesion characteristics were diameter 2 cm, Breslow index 4.4 mm, and Clark level IV. Distribution of patients per American Joint Committee on Cancer (AJCC) stage was 29%, 50%, 16%, and 7% for stages I, II, III and IV, respectively. Inguinal node metastases were unilateral in 16% and bilateral in 7%. Despite complete surgical resection, 32 patients (63%) recurred. Median survival for all patients was 41 months (range, 5-324), with 91% 5-year survival for patients with stage I and 31% for stage >or= IIA (P = 0.0002). As with cutaneous melanoma, the AJCC classification, Breslow's thickness, and Clark's levels are the major predictors of overall survival (P = 0.0001 each) and disease-free survival (P <or= 0.0001, 0.0004, and 0.0002, respectively). Surgical techniques do not seem to alter the prognosis. Because vulvar melanoma carries a poor prognosis at early stages, the use of adjuvant therapies needs to be studied prospectively in women affected with this disease." @default.
- W2003080690 created "2016-06-24" @default.
- W2003080690 creator A5032544202 @default.
- W2003080690 creator A5039023986 @default.
- W2003080690 creator A5042127830 @default.
- W2003080690 creator A5046933210 @default.
- W2003080690 creator A5053930355 @default.
- W2003080690 creator A5067847839 @default.
- W2003080690 creator A5071770443 @default.
- W2003080690 creator A5078453039 @default.
- W2003080690 creator A5082953093 @default.
- W2003080690 creator A5089486616 @default.
- W2003080690 date "2001-09-01" @default.
- W2003080690 modified "2023-10-13" @default.
- W2003080690 title "Vulvar melanoma at the M. D. Anderson Cancer Center: 25 years later" @default.
- W2003080690 cites W1489486672 @default.
- W2003080690 cites W1828940258 @default.
- W2003080690 cites W1978113416 @default.
- W2003080690 cites W1992920347 @default.
- W2003080690 cites W1999201354 @default.
- W2003080690 cites W2003935637 @default.
- W2003080690 cites W2009009494 @default.
- W2003080690 cites W2024191665 @default.
- W2003080690 cites W2026324641 @default.
- W2003080690 cites W2032243970 @default.
- W2003080690 cites W2034996544 @default.
- W2003080690 cites W2047248065 @default.
- W2003080690 cites W2060591849 @default.
- W2003080690 cites W2072657701 @default.
- W2003080690 cites W2112315252 @default.
- W2003080690 cites W2138214456 @default.
- W2003080690 cites W2396748864 @default.
- W2003080690 cites W4236323773 @default.
- W2003080690 cites W4243696303 @default.
- W2003080690 doi "https://doi.org/10.1046/j.1525-1438.2001.01043.x" @default.
- W2003080690 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11737466" @default.
- W2003080690 hasPublicationYear "2001" @default.
- W2003080690 type Work @default.
- W2003080690 sameAs 2003080690 @default.
- W2003080690 citedByCount "133" @default.
- W2003080690 countsByYear W20030806902012 @default.
- W2003080690 countsByYear W20030806902013 @default.
- W2003080690 countsByYear W20030806902014 @default.
- W2003080690 countsByYear W20030806902015 @default.
- W2003080690 countsByYear W20030806902016 @default.
- W2003080690 countsByYear W20030806902017 @default.
- W2003080690 countsByYear W20030806902018 @default.
- W2003080690 countsByYear W20030806902019 @default.
- W2003080690 countsByYear W20030806902020 @default.
- W2003080690 countsByYear W20030806902021 @default.
- W2003080690 countsByYear W20030806902022 @default.
- W2003080690 countsByYear W20030806902023 @default.
- W2003080690 crossrefType "journal-article" @default.
- W2003080690 hasAuthorship W2003080690A5032544202 @default.
- W2003080690 hasAuthorship W2003080690A5039023986 @default.
- W2003080690 hasAuthorship W2003080690A5042127830 @default.
- W2003080690 hasAuthorship W2003080690A5046933210 @default.
- W2003080690 hasAuthorship W2003080690A5053930355 @default.
- W2003080690 hasAuthorship W2003080690A5067847839 @default.
- W2003080690 hasAuthorship W2003080690A5071770443 @default.
- W2003080690 hasAuthorship W2003080690A5078453039 @default.
- W2003080690 hasAuthorship W2003080690A5082953093 @default.
- W2003080690 hasAuthorship W2003080690A5089486616 @default.
- W2003080690 hasConcept C141071460 @default.
- W2003080690 hasConcept C146357865 @default.
- W2003080690 hasConcept C151730666 @default.
- W2003080690 hasConcept C2776316342 @default.
- W2003080690 hasConcept C2777658100 @default.
- W2003080690 hasConcept C2780370617 @default.
- W2003080690 hasConcept C2781088518 @default.
- W2003080690 hasConcept C2911206564 @default.
- W2003080690 hasConcept C502942594 @default.
- W2003080690 hasConcept C50382708 @default.
- W2003080690 hasConcept C509974204 @default.
- W2003080690 hasConcept C71924100 @default.
- W2003080690 hasConcept C86803240 @default.
- W2003080690 hasConceptScore W2003080690C141071460 @default.
- W2003080690 hasConceptScore W2003080690C146357865 @default.
- W2003080690 hasConceptScore W2003080690C151730666 @default.
- W2003080690 hasConceptScore W2003080690C2776316342 @default.
- W2003080690 hasConceptScore W2003080690C2777658100 @default.
- W2003080690 hasConceptScore W2003080690C2780370617 @default.
- W2003080690 hasConceptScore W2003080690C2781088518 @default.
- W2003080690 hasConceptScore W2003080690C2911206564 @default.
- W2003080690 hasConceptScore W2003080690C502942594 @default.
- W2003080690 hasConceptScore W2003080690C50382708 @default.
- W2003080690 hasConceptScore W2003080690C509974204 @default.
- W2003080690 hasConceptScore W2003080690C71924100 @default.
- W2003080690 hasConceptScore W2003080690C86803240 @default.
- W2003080690 hasIssue "5" @default.
- W2003080690 hasLocation W20030806901 @default.
- W2003080690 hasLocation W20030806902 @default.
- W2003080690 hasOpenAccess W2003080690 @default.
- W2003080690 hasPrimaryLocation W20030806901 @default.
- W2003080690 hasRelatedWork W1978893281 @default.
- W2003080690 hasRelatedWork W2017772085 @default.
- W2003080690 hasRelatedWork W2070421634 @default.
- W2003080690 hasRelatedWork W2076286514 @default.