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- W2003082023 abstract "You have accessJournal of UrologyUrothelial Cancer: Medical & Surgical Therapy1 Apr 2013528 EXTENT OF PELVIC LYMPH NODE DISSECTION IN STRICTLY UNILATERAL TUMOR: PATHOLOGY-BASED EVIDENCE Hamed Ahmadi, Eila C. Skinner, Anne K. Schuckman, Hooman Djaladat, Jie Cai, Gus Miranda, and Siamak Daneshmand Hamed AhmadiHamed Ahmadi Los Angeles, CA More articles by this author , Eila C. SkinnerEila C. Skinner Palo Alto, CA More articles by this author , Anne K. SchuckmanAnne K. Schuckman Los Angeles, CA More articles by this author , Hooman DjaladatHooman Djaladat Los Angeles, CA More articles by this author , Jie CaiJie Cai Los Angeles, CA More articles by this author , Gus MirandaGus Miranda Los Angeles, CA More articles by this author , and Siamak DaneshmandSiamak Daneshmand Los Angeles, CA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.1922AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Some recent studies using tracer imaging modalities suggest a modified LND template may be adequate in unilateral BC (uni-BC) preserving contralateral internal iliac and bilateral above-aortic-bifurcation (AAB) regions. This study aimed at evaluating the extent and laterality of PLND in pathological uni-BC. METHODS Pathology report of patients with urothelial cell carcinoma of bladder who underwent curative radical cystectomy and ePLND at USC Institute of Urology between 1971 and 2008 were reviewed and tumors located in single bladder hemisphere were selected. Pattern of LN metastasis (LNM) including number, site, and laterality of positive LNs were evaluated. RESULTS Of 1964 patients, 347 (17.6%) patients had uni-BC (164 right-sided/183 left-sided). 81/347 (23.3%) uni-BCs had LNM which was ipsilateral in 55 (68%) and contralateral and/or bilateral in 26 (32%). Comparing site of LNM with respect to ePLND template, 72/81 (88.8%) patients had ipsilateral LNM in true pelvis region (level 1, limited to bifurcation of common iliac arteries cranially and pelvic floor caudally) while 22/81 (27.1%) patients had LNM in contralateral level 1 including internal iliac/perivesical region in 11/22 (50%) patients. LNM to contralateral common iliac (level 2 limited to aortic bifurcation cranially and bifurcation of common iliac arteries caudally) and AAB (level 3 limited to inferior mesenteric artery cranially and aortic bifurcation caudally) regions was present in 4/81 (4.9%) and 3/81 (3.7%) patients, respectively which was similar to ipsilateral LNM (3/81 (3.7%) patients in either levels) (P>0.5). CONCLUSIONS LNM to contralateral lymphatic drainage sites including internal iliac/perivesical and AAB region seems to be comparable with ipsilateral LNM in strictly unilateral BC. A bilateral ePLND including AAB region is recommended. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e216-e217 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.Metrics Author Information Hamed Ahmadi Los Angeles, CA More articles by this author Eila C. Skinner Palo Alto, CA More articles by this author Anne K. Schuckman Los Angeles, CA More articles by this author Hooman Djaladat Los Angeles, CA More articles by this author Jie Cai Los Angeles, CA More articles by this author Gus Miranda Los Angeles, CA More articles by this author Siamak Daneshmand Los Angeles, CA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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- W2003082023 title "528 EXTENT OF PELVIC LYMPH NODE DISSECTION IN STRICTLY UNILATERAL TUMOR: PATHOLOGY-BASED EVIDENCE" @default.
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