FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003089270> ?p ?o ?g. }

• W2003089270 endingPage "581" @default.
• W2003089270 startingPage "573" @default.
• W2003089270 abstract "CD44 has been described as a cell surface hyaluronan receptor present on a variety of different cells, and it is generally assumed to be prevalent in most connective tissues that contain hyaluronan. A major aim of this study was to test that presumption by localizing CD44 and hyaluronan within several tissues of the proximal tibia of the growing rat. Comparison of these profiles would reveal whether CD44 and hyaluronan co-localize with high fidelity, as would be expected if CD44 were a major hyaluronan binding protein. Using in situ hybridization and immunohistochemistry, CD44 was identified on osteoclasts, chondroclasts, osteocytes, hematopoietic marrow cells, synovial cells, and connective tissue fibroblasts (ligaments, tendons, and fascia). Although the majority of osteocytes expressed CD44, reduced expression was observed for osteoblasts and osteoprogenitor cells. Additionally, CD44 was not detected on chondrocytes from epiphyseal and metaphyseal growth cartilages or in meniscal fibrocartilage. Using biotinylated G1 domain from aggrecan and link protein, hyaluronan was observed in the maturational and hypertrophic zones of all growth cartilages, the synovium and other fibroblastic connective tissues, regional areas of the periosteum and endosteum (around osteoblasts, osteoprogenitor cells, and osteoclasts), osteocyte lacunae, and surrounding blood vessels. In regions of co-localization for CD44 and hyaluronan, it seems that CD44 is a likely hyaluronan binding protein in several tissues of the proximal tibia. However, it does not appear to be the predominant hyaluronan binding protein in growing cartilages of the weanling rat." @default.
• W2003089270 created "2016-06-24" @default.
• W2003089270 creator A5003200527 @default.
• W2003089270 creator A5009428192 @default.
• W2003089270 creator A5019539516 @default.
• W2003089270 creator A5024772304 @default.
• W2003089270 creator A5088605616 @default.
• W2003089270 creator A5089025774 @default.
• W2003089270 date "1996-07-01" @default.
• W2003089270 modified "2023-09-29" @default.
• W2003089270 title "Spatial distribution of CD44 and hyaluronan in the proximal tibia of the growing rat" @default.
• W2003089270 cites W1211643602 @default.
• W2003089270 cites W1487425110 @default.
• W2003089270 cites W1516505305 @default.
• W2003089270 cites W1571924012 @default.
• W2003089270 cites W1598762088 @default.
• W2003089270 cites W16102915 @default.
• W2003089270 cites W1847528436 @default.
• W2003089270 cites W1914681647 @default.
• W2003089270 cites W1985585224 @default.
• W2003089270 cites W1991882329 @default.
• W2003089270 cites W1994496279 @default.
• W2003089270 cites W1995015860 @default.
• W2003089270 cites W2001035036 @default.
• W2003089270 cites W2002793462 @default.
• W2003089270 cites W2007372895 @default.
• W2003089270 cites W2019053861 @default.
• W2003089270 cites W2030752849 @default.
• W2003089270 cites W2037108578 @default.
• W2003089270 cites W2037293839 @default.
• W2003089270 cites W2048799695 @default.
• W2003089270 cites W2055699737 @default.
• W2003089270 cites W2068319541 @default.
• W2003089270 cites W2069762354 @default.
• W2003089270 cites W2082665551 @default.
• W2003089270 cites W2095741501 @default.
• W2003089270 cites W2102791307 @default.
• W2003089270 cites W2131365724 @default.
• W2003089270 cites W2141386649 @default.
• W2003089270 cites W2147448836 @default.
• W2003089270 cites W2150468943 @default.
• W2003089270 cites W2151774211 @default.
• W2003089270 cites W2152797872 @default.
• W2003089270 cites W2158952594 @default.
• W2003089270 cites W2160052059 @default.
• W2003089270 cites W2160905697 @default.
• W2003089270 cites W2170326305 @default.
• W2003089270 cites W4301514960 @default.
• W2003089270 doi "https://doi.org/10.1002/jor.1100140411" @default.
• W2003089270 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8764866" @default.
• W2003089270 hasPublicationYear "1996" @default.
• W2003089270 type Work @default.
• W2003089270 sameAs 2003089270 @default.
• W2003089270 citedByCount "51" @default.
• W2003089270 countsByYear W20030892702012 @default.
• W2003089270 countsByYear W20030892702013 @default.
• W2003089270 countsByYear W20030892702015 @default.
• W2003089270 countsByYear W20030892702016 @default.
• W2003089270 countsByYear W20030892702020 @default.
• W2003089270 countsByYear W20030892702022 @default.
• W2003089270 countsByYear W20030892702023 @default.
• W2003089270 crossrefType "journal-article" @default.
• W2003089270 hasAuthorship W2003089270A5003200527 @default.
• W2003089270 hasAuthorship W2003089270A5009428192 @default.
• W2003089270 hasAuthorship W2003089270A5019539516 @default.
• W2003089270 hasAuthorship W2003089270A5024772304 @default.
• W2003089270 hasAuthorship W2003089270A5088605616 @default.
• W2003089270 hasAuthorship W2003089270A5089025774 @default.
• W2003089270 hasConcept C105702510 @default.
• W2003089270 hasConcept C142724271 @default.
• W2003089270 hasConcept C185592680 @default.
• W2003089270 hasConcept C202751555 @default.
• W2003089270 hasConcept C2777236700 @default.
• W2003089270 hasConcept C2777529286 @default.
• W2003089270 hasConcept C2778260815 @default.
• W2003089270 hasConcept C2780550940 @default.
• W2003089270 hasConcept C2780973866 @default.
• W2003089270 hasConcept C518705261 @default.
• W2003089270 hasConcept C55493867 @default.
• W2003089270 hasConcept C71924100 @default.
• W2003089270 hasConcept C86803240 @default.
• W2003089270 hasConcept C95444343 @default.
• W2003089270 hasConceptScore W2003089270C105702510 @default.
• W2003089270 hasConceptScore W2003089270C142724271 @default.
• W2003089270 hasConceptScore W2003089270C185592680 @default.
• W2003089270 hasConceptScore W2003089270C202751555 @default.
• W2003089270 hasConceptScore W2003089270C2777236700 @default.
• W2003089270 hasConceptScore W2003089270C2777529286 @default.
• W2003089270 hasConceptScore W2003089270C2778260815 @default.
• W2003089270 hasConceptScore W2003089270C2780550940 @default.
• W2003089270 hasConceptScore W2003089270C2780973866 @default.
• W2003089270 hasConceptScore W2003089270C518705261 @default.
• W2003089270 hasConceptScore W2003089270C55493867 @default.
• W2003089270 hasConceptScore W2003089270C71924100 @default.
• W2003089270 hasConceptScore W2003089270C86803240 @default.
• W2003089270 hasConceptScore W2003089270C95444343 @default.
• W2003089270 hasIssue "4" @default.
• W2003089270 hasLocation W20030892701 @default.

• next