Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003106844> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2003106844 endingPage "617" @default.
- W2003106844 startingPage "611" @default.
- W2003106844 abstract "cAMP and the cAMP-dependent protein kinase (PKA) are required in the mossy fiber pathway for both the early and the late phase of long-term potentiation (LTP). Since the CA3 region, which is the target of the mossy fibers, receives extensive noradrenergic innervation, we examined the role of beta-adrenergic receptors in mossy fiber LTP. We found that we could induce an early phase of LTP by pairing isoproterenol, a beta-adrenergic receptor agonist, with a weak train, subthreshold for LTP. This LTP was specific to the mossy fiber pathway, was blocked by inhibitors of PKA, and occluded paired-pulse facilitation, suggesting that isoproterenol was acting presynaptically. When isoproterenol was paired with a train that induced only the early phase of LTP, it gave rise to a protein synthesis-dependent late phase. Consistent with these findings, beta-adrenergic antagonists blocked both the late and the early phase of LTP induced by mossy fiber stimulation. Thus, beta-adrenergic receptor modulation is important for both phases of mossy fiber LTP." @default.
- W2003106844 created "2016-06-24" @default.
- W2003106844 creator A5001683542 @default.
- W2003106844 creator A5034071817 @default.
- W2003106844 date "1996-03-01" @default.
- W2003106844 modified "2023-09-23" @default.
- W2003106844 title "Modulation of Both the Early and the Late Phase of Mossy Fiber LTP by the Activation of β-Adrenergic Receptors" @default.
- W2003106844 cites W1511820456 @default.
- W2003106844 cites W1934090447 @default.
- W2003106844 cites W1969167894 @default.
- W2003106844 cites W1970053578 @default.
- W2003106844 cites W1970912450 @default.
- W2003106844 cites W1972770756 @default.
- W2003106844 cites W1984214648 @default.
- W2003106844 cites W1988152811 @default.
- W2003106844 cites W2008792865 @default.
- W2003106844 cites W2019551478 @default.
- W2003106844 cites W2020969390 @default.
- W2003106844 cites W2038889715 @default.
- W2003106844 cites W2051473177 @default.
- W2003106844 cites W2052969380 @default.
- W2003106844 cites W2067899373 @default.
- W2003106844 cites W2070068459 @default.
- W2003106844 cites W2090707995 @default.
- W2003106844 cites W2094988830 @default.
- W2003106844 cites W2096081604 @default.
- W2003106844 cites W2097903441 @default.
- W2003106844 cites W2108157067 @default.
- W2003106844 cites W2147608198 @default.
- W2003106844 cites W2149084718 @default.
- W2003106844 cites W2160863549 @default.
- W2003106844 cites W2172543713 @default.
- W2003106844 cites W2403704540 @default.
- W2003106844 cites W2418985282 @default.
- W2003106844 doi "https://doi.org/10.1016/s0896-6273(00)80080-x" @default.
- W2003106844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8785058" @default.
- W2003106844 hasPublicationYear "1996" @default.
- W2003106844 type Work @default.
- W2003106844 sameAs 2003106844 @default.
- W2003106844 citedByCount "187" @default.
- W2003106844 countsByYear W20031068442012 @default.
- W2003106844 countsByYear W20031068442013 @default.
- W2003106844 countsByYear W20031068442014 @default.
- W2003106844 countsByYear W20031068442015 @default.
- W2003106844 countsByYear W20031068442016 @default.
- W2003106844 countsByYear W20031068442018 @default.
- W2003106844 countsByYear W20031068442019 @default.
- W2003106844 countsByYear W20031068442020 @default.
- W2003106844 countsByYear W20031068442021 @default.
- W2003106844 countsByYear W20031068442022 @default.
- W2003106844 countsByYear W20031068442023 @default.
- W2003106844 crossrefType "journal-article" @default.
- W2003106844 hasAuthorship W2003106844A5001683542 @default.
- W2003106844 hasAuthorship W2003106844A5034071817 @default.
- W2003106844 hasBestOaLocation W20031068441 @default.
- W2003106844 hasConcept C169760540 @default.
- W2003106844 hasConcept C170493617 @default.
- W2003106844 hasConcept C185592680 @default.
- W2003106844 hasConcept C25274449 @default.
- W2003106844 hasConcept C2776464000 @default.
- W2003106844 hasConcept C2777318268 @default.
- W2003106844 hasConcept C2781161787 @default.
- W2003106844 hasConcept C55493867 @default.
- W2003106844 hasConcept C86803240 @default.
- W2003106844 hasConceptScore W2003106844C169760540 @default.
- W2003106844 hasConceptScore W2003106844C170493617 @default.
- W2003106844 hasConceptScore W2003106844C185592680 @default.
- W2003106844 hasConceptScore W2003106844C25274449 @default.
- W2003106844 hasConceptScore W2003106844C2776464000 @default.
- W2003106844 hasConceptScore W2003106844C2777318268 @default.
- W2003106844 hasConceptScore W2003106844C2781161787 @default.
- W2003106844 hasConceptScore W2003106844C55493867 @default.
- W2003106844 hasConceptScore W2003106844C86803240 @default.
- W2003106844 hasIssue "3" @default.
- W2003106844 hasLocation W20031068441 @default.
- W2003106844 hasLocation W20031068442 @default.
- W2003106844 hasOpenAccess W2003106844 @default.
- W2003106844 hasPrimaryLocation W20031068441 @default.
- W2003106844 hasRelatedWork W1044818927 @default.
- W2003106844 hasRelatedWork W1522728793 @default.
- W2003106844 hasRelatedWork W2043903807 @default.
- W2003106844 hasRelatedWork W2046140532 @default.
- W2003106844 hasRelatedWork W2054788474 @default.
- W2003106844 hasRelatedWork W2061091168 @default.
- W2003106844 hasRelatedWork W2078320306 @default.
- W2003106844 hasRelatedWork W2134927362 @default.
- W2003106844 hasRelatedWork W2164378713 @default.
- W2003106844 hasRelatedWork W3011754827 @default.
- W2003106844 hasVolume "16" @default.
- W2003106844 isParatext "false" @default.
- W2003106844 isRetracted "false" @default.
- W2003106844 magId "2003106844" @default.
- W2003106844 workType "article" @default.