FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003111130> ?p ?o ?g. }

• W2003111130 abstract "Data were examined from a day-to-day clinical practice in Yaounde, Cameroon to evaluate the efficacy and safety of peginterferon alfa-2a and ribavirin in treatment-naive Cameroonian patients with chronic hepatitis C. Ninety adults with chronic hepatitis C (mean age, 53 +/- 8 years; 79% males; 37.8% genotype 1; 23.3% genotype 2; and 38.9% genotype 4) were given at least 12 weeks of combination therapy between February 2003 and August 2007. Of these, 54 completed the treatment and the 24-week follow up. Subsequently, 18 continued treatment and 18 (20%) discontinued the treatment, 6 (6.7%) due to adverse effects. An intention-to-treat analysis showed that 38 (52.8%) had an end-of-treatment virologic response and 34 (47.2%) had a sustained virologic response. Sustained virologic response were significantly higher among patients with hepatitis C virus (HCV) genotype 2 (83.4%) than in those with genotype 1 (31%) or genotype 4 (42.3%) (P < 0.05). Non HCV-2 genotype, pretreatment fibrosis score >2, HCV RNA level >8.0 x 10(5) IU/ml and a non-virologic response at 12 weeks of treatment were associated with poor sustained virologic response (P < 0.05). Thus, HCV can be treated in a Sub-Saharan African country. It indicates that Cameroonian HCV-1 and -4 patients have a poorer sustained virologic response than the published results for Western and Middle-East countries. Virus subtype may influence the treatment outcome, since there is a great genetic diversity within Cameroonian HCV-1 and -4 genotypes." @default.
• W2003111130 created "2016-06-24" @default.
• W2003111130 creator A5011479029 @default.
• W2003111130 creator A5027739167 @default.
• W2003111130 creator A5030842281 @default.
• W2003111130 creator A5043749772 @default.
• W2003111130 creator A5053925040 @default.
• W2003111130 creator A5068619351 @default.
• W2003111130 creator A5091097290 @default.
• W2003111130 date "2008-12-01" @default.
• W2003111130 modified "2023-09-25" @default.
• W2003111130 title "Efficacy and safety of peginterferon alpha-2a/ribavirin in treatment-naive Cameroonian patients with chronic hepatitis C" @default.
• W2003111130 cites W1585269270 @default.
• W2003111130 cites W1980095859 @default.
• W2003111130 cites W1980390916 @default.
• W2003111130 cites W1983787411 @default.
• W2003111130 cites W1984175031 @default.
• W2003111130 cites W1985241178 @default.
• W2003111130 cites W1992239172 @default.
• W2003111130 cites W1995724407 @default.
• W2003111130 cites W2000558757 @default.
• W2003111130 cites W2007217713 @default.
• W2003111130 cites W2018446644 @default.
• W2003111130 cites W2020914906 @default.
• W2003111130 cites W2023481708 @default.
• W2003111130 cites W2024049300 @default.
• W2003111130 cites W2027545702 @default.
• W2003111130 cites W2030805412 @default.
• W2003111130 cites W2046035065 @default.
• W2003111130 cites W2048820054 @default.
• W2003111130 cites W2051627308 @default.
• W2003111130 cites W2053702303 @default.
• W2003111130 cites W2063089198 @default.
• W2003111130 cites W2065986600 @default.
• W2003111130 cites W2068431603 @default.
• W2003111130 cites W2077719713 @default.
• W2003111130 cites W2091457692 @default.
• W2003111130 cites W2102169576 @default.
• W2003111130 cites W2107639148 @default.
• W2003111130 cites W2127685726 @default.
• W2003111130 cites W2129272218 @default.
• W2003111130 cites W2132503465 @default.
• W2003111130 cites W2156047935 @default.
• W2003111130 cites W2156763082 @default.
• W2003111130 cites W2165297688 @default.
• W2003111130 cites W2168911689 @default.
• W2003111130 cites W2182218967 @default.
• W2003111130 doi "https://doi.org/10.1002/jmv.21319" @default.
• W2003111130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19040282" @default.
• W2003111130 hasPublicationYear "2008" @default.
• W2003111130 type Work @default.
• W2003111130 sameAs 2003111130 @default.
• W2003111130 citedByCount "11" @default.
• W2003111130 countsByYear W20031111302012 @default.
• W2003111130 countsByYear W20031111302013 @default.
• W2003111130 countsByYear W20031111302014 @default.
• W2003111130 countsByYear W20031111302015 @default.
• W2003111130 countsByYear W20031111302016 @default.
• W2003111130 crossrefType "journal-article" @default.
• W2003111130 hasAuthorship W2003111130A5011479029 @default.
• W2003111130 hasAuthorship W2003111130A5027739167 @default.
• W2003111130 hasAuthorship W2003111130A5030842281 @default.
• W2003111130 hasAuthorship W2003111130A5043749772 @default.
• W2003111130 hasAuthorship W2003111130A5053925040 @default.
• W2003111130 hasAuthorship W2003111130A5068619351 @default.
• W2003111130 hasAuthorship W2003111130A5091097290 @default.
• W2003111130 hasConcept C104317684 @default.
• W2003111130 hasConcept C126322002 @default.
• W2003111130 hasConcept C135763542 @default.
• W2003111130 hasConcept C159047783 @default.
• W2003111130 hasConcept C197934379 @default.
• W2003111130 hasConcept C203014093 @default.
• W2003111130 hasConcept C2522874641 @default.
• W2003111130 hasConcept C2776408679 @default.
• W2003111130 hasConcept C2776455275 @default.
• W2003111130 hasConcept C2780040827 @default.
• W2003111130 hasConcept C3020491458 @default.
• W2003111130 hasConcept C55493867 @default.
• W2003111130 hasConcept C71924100 @default.
• W2003111130 hasConcept C86803240 @default.
• W2003111130 hasConcept C90924648 @default.
• W2003111130 hasConceptScore W2003111130C104317684 @default.
• W2003111130 hasConceptScore W2003111130C126322002 @default.
• W2003111130 hasConceptScore W2003111130C135763542 @default.
• W2003111130 hasConceptScore W2003111130C159047783 @default.
• W2003111130 hasConceptScore W2003111130C197934379 @default.
• W2003111130 hasConceptScore W2003111130C203014093 @default.
• W2003111130 hasConceptScore W2003111130C2522874641 @default.
• W2003111130 hasConceptScore W2003111130C2776408679 @default.
• W2003111130 hasConceptScore W2003111130C2776455275 @default.
• W2003111130 hasConceptScore W2003111130C2780040827 @default.
• W2003111130 hasConceptScore W2003111130C3020491458 @default.
• W2003111130 hasConceptScore W2003111130C55493867 @default.
• W2003111130 hasConceptScore W2003111130C71924100 @default.
• W2003111130 hasConceptScore W2003111130C86803240 @default.
• W2003111130 hasConceptScore W2003111130C90924648 @default.
• W2003111130 hasLocation W20031111301 @default.
• W2003111130 hasLocation W20031111302 @default.
• W2003111130 hasLocation W20031111303 @default.
• W2003111130 hasLocation W20031111304 @default.

• next