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• W2003113863 endingPage "1232" @default.
• W2003113863 startingPage "1220" @default.
• W2003113863 abstract "Cholesterol plays an important role in synapse formation, receptor function, and synaptic plasticity, and animal studies show that modifying cholesterol may improve learning and memory. Other data show that feeding animals cholesterol can induce beta amyloid accumulation. Rabbits (Oryctolagus cuniculus) fed 2% cholesterol for 8 weeks were given trace conditioning of the nictitating membrane response using a 100-ms tone, a 700-ms trace, and periorbital electrical stimulation or airpuff. Rabbits fed cholesterol showed significant facilitation of trace conditioning to airpuff and conditioning-specific reflex modification to periorbital electrical stimulation and airpuff. The cholesterol-fed rabbits had beta amyloid accumulation in the cortex, but little in the hippocampus. The data suggest cholesterol had facilitative effects that outweighed potential amnesic effects of cortical beta amyloid." @default.
• W2003113863 created "2016-06-24" @default.
• W2003113863 creator A5019519860 @default.
• W2003113863 creator A5020555073 @default.
• W2003113863 creator A5071694271 @default.
• W2003113863 creator A5072877944 @default.
• W2003113863 date "2003-01-01" @default.
• W2003113863 modified "2023-09-25" @default.
• W2003113863 title "Cholesterol Modifies Classical Conditioning of the Rabbit (Oryctolagus cuniculus) Nictitating Membrane Response." @default.
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