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- W2003123504 abstract "In this study, we considered the interplay between the efficiency and cytotoxicity of multicomponent cationic liposome/DNA complexes, in cell lines of different origin, as NIH 3T3, HEK 293T, N18TG2, and SK-N-SH. We show that both efficiency and cytotoxicity vary considerably depending on used transfection agents and cells lines. Such variations are largely overcome when transfection is evaluated by a parameter, R, that combines the percentages of transfected, nonviable, and nonadherent cells. These findings provide a strong validation of R as an unbiased indicator for transfection performance across cell lines and transfection agents." @default.
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- W2003123504 date "2010-10-11" @default.
- W2003123504 modified "2023-09-27" @default.
- W2003123504 title "Toward an objective evaluation of cell transfection performance" @default.
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- W2003123504 doi "https://doi.org/10.1063/1.3499756" @default.
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