FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003125670> ?p ?o ?g. }

• W2003125670 endingPage "135" @default.
• W2003125670 startingPage "128" @default.
• W2003125670 abstract "To examine the relationship between serum levels of interleukin-1 receptor antagonist (IL-1Ra) and its gene expression in peripheral blood mononuclear cells (PBMC) from patients with polymyositis and dermatomyositis (PM/DM).IL-1Ra levels in sera from patients and supernatants of unstimulated monocyte cultures were measured by enzyme-linked immunosorbent assay. Expression of IL-1Ra mRNA was analyzed by Northern blotting, and an 86-base pair variable repeat polymorphism in intron 2 of the IL-1Ra gene was determined by polymerase chain reaction.Serum IL-1Ra was significantly elevated in 27 patients with active-stage PM/DM when compared with levels in 16 patients with inactive-stage PM/DM and 19 normal controls. Serum concentrations of IL-1Ra were correlated with PM/DM disease activity. IL-1Ra mRNA was detected in freshly isolated PBMC from patients with active-stage PM/DM, but not in controls. Moreover, IL-1Ra concentrations were increased significantly in unstimulated monocytes from patients with active-stage PM/DM compared with monocytes from normal controls. However, there were no significant differences in IL-1Ra allele frequencies between patients and normal controls.Elevation of both IL-1Ra mRNA and protein in sera of patients with active-stage PM/DM suggest that higher levels of serum IL-1Ra may reflect increased IL-1Ra production in myositis, and that IL-1Ra may regulate IL-1-mediated muscle fiber damage in PM/DM." @default.
• W2003125670 created "2016-06-24" @default.
• W2003125670 creator A5005942636 @default.
• W2003125670 creator A5006350361 @default.
• W2003125670 creator A5029321053 @default.
• W2003125670 creator A5029346194 @default.
• W2003125670 creator A5037552973 @default.
• W2003125670 creator A5085330090 @default.
• W2003125670 date "2000-01-01" @default.
• W2003125670 modified "2023-09-30" @default.
• W2003125670 title "Abnormal IL-1 Receptor Antagonist Production in Patients with Polymyositis and Dermatomyositis." @default.
• W2003125670 cites W1513178777 @default.
• W2003125670 cites W1514195725 @default.
• W2003125670 cites W1556136861 @default.
• W2003125670 cites W1968858741 @default.
• W2003125670 cites W1976912157 @default.
• W2003125670 cites W1986288022 @default.
• W2003125670 cites W1989459539 @default.
• W2003125670 cites W1990051204 @default.
• W2003125670 cites W1997404037 @default.
• W2003125670 cites W1997895757 @default.
• W2003125670 cites W2000605890 @default.
• W2003125670 cites W2005313701 @default.
• W2003125670 cites W2007531718 @default.
• W2003125670 cites W2009957587 @default.
• W2003125670 cites W2021238379 @default.
• W2003125670 cites W2025563824 @default.
• W2003125670 cites W2028071555 @default.
• W2003125670 cites W2048468332 @default.
• W2003125670 cites W2055312155 @default.
• W2003125670 cites W2061347355 @default.
• W2003125670 cites W2062680329 @default.
• W2003125670 cites W2063765445 @default.
• W2003125670 cites W2070382042 @default.
• W2003125670 cites W2074150791 @default.
• W2003125670 cites W2077235727 @default.
• W2003125670 cites W2081874501 @default.
• W2003125670 cites W2083955105 @default.
• W2003125670 cites W2092243995 @default.
• W2003125670 cites W2113869393 @default.
• W2003125670 cites W2115871198 @default.
• W2003125670 cites W2135483305 @default.
• W2003125670 cites W2139091401 @default.
• W2003125670 cites W2152538354 @default.
• W2003125670 cites W2162259784 @default.
• W2003125670 cites W2395263054 @default.
• W2003125670 cites W2413305680 @default.
• W2003125670 cites W2419265930 @default.
• W2003125670 cites W2419407572 @default.
• W2003125670 cites W3024870353 @default.
• W2003125670 doi "https://doi.org/10.2169/internalmedicine.39.128" @default.
• W2003125670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10732829" @default.
• W2003125670 hasPublicationYear "2000" @default.
• W2003125670 type Work @default.
• W2003125670 sameAs 2003125670 @default.
• W2003125670 citedByCount "30" @default.
• W2003125670 countsByYear W20031256702012 @default.
• W2003125670 countsByYear W20031256702013 @default.
• W2003125670 countsByYear W20031256702014 @default.
• W2003125670 countsByYear W20031256702015 @default.
• W2003125670 countsByYear W20031256702020 @default.
• W2003125670 countsByYear W20031256702023 @default.
• W2003125670 crossrefType "journal-article" @default.
• W2003125670 hasAuthorship W2003125670A5005942636 @default.
• W2003125670 hasAuthorship W2003125670A5006350361 @default.
• W2003125670 hasAuthorship W2003125670A5029321053 @default.
• W2003125670 hasAuthorship W2003125670A5029346194 @default.
• W2003125670 hasAuthorship W2003125670A5037552973 @default.
• W2003125670 hasAuthorship W2003125670A5085330090 @default.
• W2003125670 hasBestOaLocation W20031256701 @default.
• W2003125670 hasConcept C11988809 @default.
• W2003125670 hasConcept C126322002 @default.
• W2003125670 hasConcept C134018914 @default.
• W2003125670 hasConcept C137061746 @default.
• W2003125670 hasConcept C149892131 @default.
• W2003125670 hasConcept C170493617 @default.
• W2003125670 hasConcept C202751555 @default.
• W2003125670 hasConcept C203014093 @default.
• W2003125670 hasConcept C2776885963 @default.
• W2003125670 hasConcept C2776914184 @default.
• W2003125670 hasConcept C2778122271 @default.
• W2003125670 hasConcept C2778690821 @default.
• W2003125670 hasConcept C2778751314 @default.
• W2003125670 hasConcept C2779387793 @default.
• W2003125670 hasConcept C55493867 @default.
• W2003125670 hasConcept C71924100 @default.
• W2003125670 hasConcept C74172505 @default.
• W2003125670 hasConcept C86803240 @default.
• W2003125670 hasConceptScore W2003125670C11988809 @default.
• W2003125670 hasConceptScore W2003125670C126322002 @default.
• W2003125670 hasConceptScore W2003125670C134018914 @default.
• W2003125670 hasConceptScore W2003125670C137061746 @default.
• W2003125670 hasConceptScore W2003125670C149892131 @default.
• W2003125670 hasConceptScore W2003125670C170493617 @default.
• W2003125670 hasConceptScore W2003125670C202751555 @default.
• W2003125670 hasConceptScore W2003125670C203014093 @default.
• W2003125670 hasConceptScore W2003125670C2776885963 @default.
• W2003125670 hasConceptScore W2003125670C2776914184 @default.

• next