FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003130094> ?p ?o ?g. }

• W2003130094 endingPage "255" @default.
• W2003130094 startingPage "244" @default.
• W2003130094 abstract "Hollow fiber scaffolds that compartmentalize axonal processes from their cell bodies can enable neuronal cultures with directed neurite outgrowth within a three-dimensional (3-D) space for controlling neuronal cell networking in vitro. Controllable 3-D neuronal networks in vitro could provide tools for studying neurobiological events. In order to create such a scaffold, polyethersulfone (PES) microporous hollow fibers were ablated with a KrF excimer laser to generate specifically designed channels for directing neurite outgrowth into the luminal compartments of the fibers. Excimer laser modification is demonstrated as a reproducible method to generate 5microm diameter channels within PES hollow fiber walls that allow compartmentalization of neuronal cell bodies from their axons. Laser modification of counterpart flat sheet PES membranes with peak surface fluences of 1.2Jcm(-2) results in increased hydrophobicity and laminin adsorption on the surface compared with the unmodified PES surface. This is correlated to enhanced PC12 cell adhesion with increasing fluence onto laser-modified PES membrane surfaces coated with laminin when compared with unmodified surfaces. Adult rat neural progenitor cells differentiated on PES fibers with laser-created channels resulted in spontaneous cell process growth into the channels of the scaffold wall while preventing entrance of cell bodies. Therefore, laser-modified PES fibers serve as scaffolds with channels conducive to directing neuronal cell process growth. These hollow fiber scaffolds can potentially be used in combination with perfusion and oxygenation hollow fiber membrane sets to construct a hollow fiber-based 3-D bioreactor for controlling and studying in vitro neuronal networking in three dimensions between compartmentalized cultures." @default.
• W2003130094 created "2016-06-24" @default.
• W2003130094 creator A5006706931 @default.
• W2003130094 creator A5016925930 @default.
• W2003130094 creator A5022954767 @default.
• W2003130094 creator A5035429910 @default.
• W2003130094 creator A5064885490 @default.
• W2003130094 date "2008-03-01" @default.
• W2003130094 modified "2023-09-27" @default.
• W2003130094 title "Excimer laser channel creation in polyethersulfone hollow fibers for compartmentalized in vitro neuronal cell culture scaffolds" @default.
• W2003130094 cites W110398411 @default.
• W2003130094 cites W1485806448 @default.
• W2003130094 cites W1487175372 @default.
• W2003130094 cites W1585284682 @default.
• W2003130094 cites W1900293717 @default.
• W2003130094 cites W1964958432 @default.
• W2003130094 cites W1966655369 @default.
• W2003130094 cites W1967880112 @default.
• W2003130094 cites W1969170545 @default.
• W2003130094 cites W1969644354 @default.
• W2003130094 cites W1970435814 @default.
• W2003130094 cites W1971969398 @default.
• W2003130094 cites W1972376128 @default.
• W2003130094 cites W1972969430 @default.
• W2003130094 cites W1974587859 @default.
• W2003130094 cites W1974860935 @default.
• W2003130094 cites W1981896102 @default.
• W2003130094 cites W1985499103 @default.
• W2003130094 cites W1988640032 @default.
• W2003130094 cites W1991504043 @default.
• W2003130094 cites W1992516396 @default.
• W2003130094 cites W1995797880 @default.
• W2003130094 cites W2002545202 @default.
• W2003130094 cites W2002953797 @default.
• W2003130094 cites W2005165360 @default.
• W2003130094 cites W2005484961 @default.
• W2003130094 cites W2006501418 @default.
• W2003130094 cites W2007260979 @default.
• W2003130094 cites W2008304769 @default.
• W2003130094 cites W2017412267 @default.
• W2003130094 cites W2018475086 @default.
• W2003130094 cites W2029890974 @default.
• W2003130094 cites W2032420735 @default.
• W2003130094 cites W2037672000 @default.
• W2003130094 cites W2037729390 @default.
• W2003130094 cites W2040572520 @default.
• W2003130094 cites W2040776883 @default.
• W2003130094 cites W2041723792 @default.
• W2003130094 cites W2044317027 @default.
• W2003130094 cites W2044396243 @default.
• W2003130094 cites W2047608799 @default.
• W2003130094 cites W2048291950 @default.
• W2003130094 cites W2048708035 @default.
• W2003130094 cites W2052262017 @default.
• W2003130094 cites W2053552455 @default.
• W2003130094 cites W2059392990 @default.
• W2003130094 cites W2062150858 @default.
• W2003130094 cites W2063551829 @default.
• W2003130094 cites W2066532637 @default.
• W2003130094 cites W2067065320 @default.
• W2003130094 cites W2067938476 @default.
• W2003130094 cites W2071507584 @default.
• W2003130094 cites W2077994589 @default.
• W2003130094 cites W2079138835 @default.
• W2003130094 cites W2081598933 @default.
• W2003130094 cites W2083064112 @default.
• W2003130094 cites W2083098082 @default.
• W2003130094 cites W2083886698 @default.
• W2003130094 cites W2083910200 @default.
• W2003130094 cites W2084329486 @default.
• W2003130094 cites W2087399647 @default.
• W2003130094 cites W2089152600 @default.
• W2003130094 cites W2091872903 @default.
• W2003130094 cites W2096346316 @default.
• W2003130094 cites W2097677809 @default.
• W2003130094 cites W2116800744 @default.
• W2003130094 cites W2130925061 @default.
• W2003130094 cites W2135907032 @default.
• W2003130094 cites W2141413307 @default.
• W2003130094 cites W2141687371 @default.
• W2003130094 cites W2150353081 @default.
• W2003130094 cites W2176312328 @default.
• W2003130094 cites W2413991229 @default.
• W2003130094 cites W2416324448 @default.
• W2003130094 cites W4213380953 @default.
• W2003130094 cites W4232534952 @default.
• W2003130094 cites W4242979567 @default.
• W2003130094 doi "https://doi.org/10.1016/j.actbio.2007.10.004" @default.
• W2003130094 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18060849" @default.
• W2003130094 hasPublicationYear "2008" @default.
• W2003130094 type Work @default.
• W2003130094 sameAs 2003130094 @default.
• W2003130094 citedByCount "37" @default.
• W2003130094 countsByYear W20031300942012 @default.
• W2003130094 countsByYear W20031300942013 @default.
• W2003130094 countsByYear W20031300942014 @default.
• W2003130094 countsByYear W20031300942015 @default.
• W2003130094 countsByYear W20031300942016 @default.

• next