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- W2003131161 abstract "The non-steroidal anti-inflammatory agent (NSAID) flunixin was administered as single doses both orally and intravenously to six cats at a dose rate of 1.0 mg/ kg in a two-part cross-over study. After oral dosing rapid absorption to a mean peak concentration of 2.586 μg/ml occurred at a mean time of 1.33 h. Similar mean plasma concentration-time AUC values for oral and intravenous dosing indicated that absorption by the former route was virtually complete. The decline in plasma concentration occurred fairly rapidly with both routes, and elimination half-life was approximately 1.0–1.5 h. The time course of inhibition of serum TXB2 concentration was similar for the two routes of administration, suggesting that similar dosing schedules are likely to be appropriate for evaluation of flunixin in clinical trials." @default.
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- W2003131161 title "Pharmacodynamics and pharmacokinetics of flunixin in the cat" @default.
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- W2003131161 doi "https://doi.org/10.1016/0007-1935(91)90002-5" @default.
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