FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003141402> ?p ?o ?g. }

• W2003141402 endingPage "374" @default.
• W2003141402 startingPage "367" @default.
• W2003141402 abstract "One of the most frequent subtypes of constipation is represented by obstructed defecation, and it has recently been reported that these patients may have colonic motor abnormalities in addition to alterations of the anorectal area. However, it is unknown whether these patients display abnormalities of the enteric nervous system, as reported in other groups of constipated subjects. For this reason, we evaluated the neuropathologic aspects of the enteric nervous system in a homogeneous group of patients with obstructed defecation. Colonic specimens from 11 patients (nine women, age range 39-66 years) undergoing surgery for symptoms refractory to any therapeutic measure, including biofeedback training, were obtained and examined by means of conventional histological methods and immunohistochemistry (NSE, S100, c-Kit, formamide-mAb, Bcl-2, CD34, alfa-actin). Analysis of the specimens showed that the enteric neurons were significantly decreased only in the submucosal plexus of patients (P<0.0001 vs controls), whereas the enteric glial cells of constipated patients were reduced in both the myenteric (P=0.018 vs controls) and the submucosal plexus (P=0.004 vs controls). No difference between patients and controls were found concerning c-Kit and CD34 expression, and the number of apoptotic neurons. These findings support the concept that at least a subgroup of patients with obstructed defecation and severe, intractable symptoms display abnormalities of the enteric nervous system, mostly related to the enteric glial cells. These findings might explain some of the pathophysiological abnormalities, and help to better understand this condition." @default.
• W2003141402 created "2016-06-24" @default.
• W2003141402 creator A5013598906 @default.
• W2003141402 creator A5014366972 @default.
• W2003141402 creator A5033621477 @default.
• W2003141402 creator A5045823316 @default.
• W2003141402 creator A5057405366 @default.
• W2003141402 creator A5057745508 @default.
• W2003141402 creator A5058837422 @default.
• W2003141402 creator A5072623709 @default.
• W2003141402 creator A5075757405 @default.
• W2003141402 creator A5082173292 @default.
• W2003141402 creator A5086001594 @default.
• W2003141402 date "2007-03-01" @default.
• W2003141402 modified "2023-10-02" @default.
• W2003141402 title "Colonic neuropathological aspects in patients with intractable constipation due to obstructed defecation" @default.
• W2003141402 cites W1848094944 @default.
• W2003141402 cites W1964617786 @default.
• W2003141402 cites W1967825344 @default.
• W2003141402 cites W1969549273 @default.
• W2003141402 cites W1973221568 @default.
• W2003141402 cites W1973936420 @default.
• W2003141402 cites W1977544665 @default.
• W2003141402 cites W1986512377 @default.
• W2003141402 cites W1988021161 @default.
• W2003141402 cites W1994891058 @default.
• W2003141402 cites W2000065523 @default.
• W2003141402 cites W2000793260 @default.
• W2003141402 cites W2001613541 @default.
• W2003141402 cites W2008330905 @default.
• W2003141402 cites W2008838600 @default.
• W2003141402 cites W2011848992 @default.
• W2003141402 cites W2014182881 @default.
• W2003141402 cites W2014185005 @default.
• W2003141402 cites W2017702978 @default.
• W2003141402 cites W2017708435 @default.
• W2003141402 cites W2021273608 @default.
• W2003141402 cites W2023087961 @default.
• W2003141402 cites W2036835672 @default.
• W2003141402 cites W2039373896 @default.
• W2003141402 cites W2049588755 @default.
• W2003141402 cites W2054723469 @default.
• W2003141402 cites W2055407049 @default.
• W2003141402 cites W2057339618 @default.
• W2003141402 cites W2058416199 @default.
• W2003141402 cites W2058801198 @default.
• W2003141402 cites W2060961825 @default.
• W2003141402 cites W2077656589 @default.
• W2003141402 cites W2083745882 @default.
• W2003141402 cites W2088838777 @default.
• W2003141402 cites W2095464607 @default.
• W2003141402 cites W2096371238 @default.
• W2003141402 cites W2100972831 @default.
• W2003141402 cites W2105370473 @default.
• W2003141402 cites W2110392434 @default.
• W2003141402 cites W2113148955 @default.
• W2003141402 cites W2121277395 @default.
• W2003141402 cites W2127557160 @default.
• W2003141402 cites W2129967196 @default.
• W2003141402 cites W2138922448 @default.
• W2003141402 cites W2141388802 @default.
• W2003141402 cites W2151900782 @default.
• W2003141402 cites W2162344902 @default.
• W2003141402 cites W2166386674 @default.
• W2003141402 cites W2169063511 @default.
• W2003141402 cites W250475567 @default.
• W2003141402 cites W2611380183 @default.
• W2003141402 cites W4229792731 @default.
• W2003141402 cites W4246002938 @default.
• W2003141402 cites W4296246874 @default.
• W2003141402 doi "https://doi.org/10.1038/modpathol.3800748" @default.
• W2003141402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17277762" @default.
• W2003141402 hasPublicationYear "2007" @default.
• W2003141402 type Work @default.
• W2003141402 sameAs 2003141402 @default.
• W2003141402 citedByCount "30" @default.
• W2003141402 countsByYear W20031414022012 @default.
• W2003141402 countsByYear W20031414022013 @default.
• W2003141402 countsByYear W20031414022015 @default.
• W2003141402 countsByYear W20031414022016 @default.
• W2003141402 countsByYear W20031414022017 @default.
• W2003141402 countsByYear W20031414022018 @default.
• W2003141402 countsByYear W20031414022020 @default.
• W2003141402 countsByYear W20031414022021 @default.
• W2003141402 countsByYear W20031414022022 @default.
• W2003141402 crossrefType "journal-article" @default.
• W2003141402 hasAuthorship W2003141402A5013598906 @default.
• W2003141402 hasAuthorship W2003141402A5014366972 @default.
• W2003141402 hasAuthorship W2003141402A5033621477 @default.
• W2003141402 hasAuthorship W2003141402A5045823316 @default.
• W2003141402 hasAuthorship W2003141402A5057405366 @default.
• W2003141402 hasAuthorship W2003141402A5057745508 @default.
• W2003141402 hasAuthorship W2003141402A5058837422 @default.
• W2003141402 hasAuthorship W2003141402A5072623709 @default.
• W2003141402 hasAuthorship W2003141402A5075757405 @default.
• W2003141402 hasAuthorship W2003141402A5082173292 @default.
• W2003141402 hasAuthorship W2003141402A5086001594 @default.
• W2003141402 hasBestOaLocation W20031414021 @default.

• next