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- W2003143321 abstract "Small RNAs are not only involved in post-transcriptional gene silencing in the cytoplasm, but also modulate activities of the nuclear genome. Although silencing of mRNAs involves RNA-RNA base-pairing, it remains unclear whether the RNAi machinery responsible for chromatin or DNA modification interacts with DNA or RNA. The identification of an RNA helicase required for chromatin-Argonaute protein interaction as well as the presence of Argonaute-associated long non-coding transcripts in Tetrahymena suggest the presence of RNA-RNA interactions prior to small RNA-induced heterochromatin formation in ciliates." @default.
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- W2003143321 date "2009-04-01" @default.
- W2003143321 modified "2023-09-25" @default.
- W2003143321 title "Non-coding RNA: A bridge between small RNA and DNA" @default.
- W2003143321 doi "https://doi.org/10.4161/rna.6.2.7792" @default.
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