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- W2003145462 abstract "Abstract Soluble rat striatal tyrosine hydroxylase is activated by low concentrations (0.006–0.008%) of the anionic detergent sodium dodecyl sulfate (SDS). After treatment with the detergent, the enzyme exhibits a Km for cofactor decreased by an order of magnitude, and concamitantly loses the ability to be activated by the specific sulfated polysaccharide heparin (2). The identical effects of both effectors on the kinetic properties of the enzyme suggest that tyrosine hydroxylase is susceptible to specific conformational transitions which modulate its kinetic state." @default.
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- W2003145462 date "1974-06-01" @default.
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- W2003145462 title "Effect of sodium dodecyl sulfate on the kinetic properties and molecular weight of rat striatal tyrosine hydroxylase" @default.
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- W2003145462 doi "https://doi.org/10.1016/0024-3205(74)90133-7" @default.
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