Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003147114> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2003147114 endingPage "690" @default.
- W2003147114 startingPage "687" @default.
- W2003147114 abstract "Interferon-gamma stimulates major histocompatibility complex (MHC) class I antigen processing and presentation by inducing the expression of major histocompatibility complex class I heavy chains, beta2-microglobulin, the transporter associated with antigen processing, and components of the proteasome complex. We demonstrate that this effect of interferon-gamma on the major histocompatibility complex class I pathway is inhibited in human cytomegalovirus-infected fibroblasts and endothelial cells. This is the result of a direct human cytomegalovirus/cell interaction leading to a block in interferon-gamma signal transduction beginning at early times after infection and peaking at 72 hr after infection. These observations suggest a novel level of herpesvirus interference with antigen processing: protection of infected cells from the immunoregulatory effects of interferon-gamma. Thus protected, human cytomegalovirus persists and may exacerbate graft rejection or lead to fulminant infection in the immunocompromised transplant recipient." @default.
- W2003147114 created "2016-06-24" @default.
- W2003147114 creator A5016039997 @default.
- W2003147114 creator A5024780472 @default.
- W2003147114 creator A5035574844 @default.
- W2003147114 creator A5042764752 @default.
- W2003147114 creator A5074277827 @default.
- W2003147114 creator A5079256968 @default.
- W2003147114 creator A5081998792 @default.
- W2003147114 date "2000-02-01" @default.
- W2003147114 modified "2023-09-23" @default.
- W2003147114 title "HUMAN CYTOMEGALOVIRUS BLOCKS INTERFERON-?? STIMULATED UP-REGULATION OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I EXPRESSION AND THE CLASS I ANTIGEN PROCESSING MACHINERY1" @default.
- W2003147114 cites W1568041502 @default.
- W2003147114 cites W2009607549 @default.
- W2003147114 cites W2022819740 @default.
- W2003147114 cites W2029275361 @default.
- W2003147114 cites W2041112289 @default.
- W2003147114 cites W2056145969 @default.
- W2003147114 cites W2057272534 @default.
- W2003147114 cites W2065095749 @default.
- W2003147114 cites W2085279345 @default.
- W2003147114 doi "https://doi.org/10.1097/00007890-200002270-00040" @default.
- W2003147114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10708135" @default.
- W2003147114 hasPublicationYear "2000" @default.
- W2003147114 type Work @default.
- W2003147114 sameAs 2003147114 @default.
- W2003147114 citedByCount "17" @default.
- W2003147114 countsByYear W20031471142014 @default.
- W2003147114 crossrefType "journal-article" @default.
- W2003147114 hasAuthorship W2003147114A5016039997 @default.
- W2003147114 hasAuthorship W2003147114A5024780472 @default.
- W2003147114 hasAuthorship W2003147114A5035574844 @default.
- W2003147114 hasAuthorship W2003147114A5042764752 @default.
- W2003147114 hasAuthorship W2003147114A5074277827 @default.
- W2003147114 hasAuthorship W2003147114A5079256968 @default.
- W2003147114 hasAuthorship W2003147114A5081998792 @default.
- W2003147114 hasBestOaLocation W20031471141 @default.
- W2003147114 hasConcept C108249834 @default.
- W2003147114 hasConcept C147483822 @default.
- W2003147114 hasConcept C159047783 @default.
- W2003147114 hasConcept C170627219 @default.
- W2003147114 hasConcept C203014093 @default.
- W2003147114 hasConcept C207936829 @default.
- W2003147114 hasConcept C2522874641 @default.
- W2003147114 hasConcept C2776090121 @default.
- W2003147114 hasConcept C2776178377 @default.
- W2003147114 hasConcept C2779820661 @default.
- W2003147114 hasConcept C2780841837 @default.
- W2003147114 hasConcept C83464605 @default.
- W2003147114 hasConcept C86803240 @default.
- W2003147114 hasConcept C8891405 @default.
- W2003147114 hasConceptScore W2003147114C108249834 @default.
- W2003147114 hasConceptScore W2003147114C147483822 @default.
- W2003147114 hasConceptScore W2003147114C159047783 @default.
- W2003147114 hasConceptScore W2003147114C170627219 @default.
- W2003147114 hasConceptScore W2003147114C203014093 @default.
- W2003147114 hasConceptScore W2003147114C207936829 @default.
- W2003147114 hasConceptScore W2003147114C2522874641 @default.
- W2003147114 hasConceptScore W2003147114C2776090121 @default.
- W2003147114 hasConceptScore W2003147114C2776178377 @default.
- W2003147114 hasConceptScore W2003147114C2779820661 @default.
- W2003147114 hasConceptScore W2003147114C2780841837 @default.
- W2003147114 hasConceptScore W2003147114C83464605 @default.
- W2003147114 hasConceptScore W2003147114C86803240 @default.
- W2003147114 hasConceptScore W2003147114C8891405 @default.
- W2003147114 hasIssue "4" @default.
- W2003147114 hasLocation W20031471141 @default.
- W2003147114 hasLocation W20031471142 @default.
- W2003147114 hasLocation W20031471143 @default.
- W2003147114 hasOpenAccess W2003147114 @default.
- W2003147114 hasPrimaryLocation W20031471141 @default.
- W2003147114 hasRelatedWork W1526753793 @default.
- W2003147114 hasRelatedWork W1537917185 @default.
- W2003147114 hasRelatedWork W1548452743 @default.
- W2003147114 hasRelatedWork W2003147114 @default.
- W2003147114 hasRelatedWork W2006653421 @default.
- W2003147114 hasRelatedWork W2023617760 @default.
- W2003147114 hasRelatedWork W2110561490 @default.
- W2003147114 hasRelatedWork W2171532735 @default.
- W2003147114 hasRelatedWork W2396522833 @default.
- W2003147114 hasRelatedWork W4313354691 @default.
- W2003147114 hasVolume "69" @default.
- W2003147114 isParatext "false" @default.
- W2003147114 isRetracted "false" @default.
- W2003147114 magId "2003147114" @default.
- W2003147114 workType "article" @default.