FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003158984> ?p ?o ?g. }

• W2003158984 endingPage "1123" @default.
• W2003158984 startingPage "1117" @default.
• W2003158984 abstract "ABSTRACT The paramyxovirus nucleoproteins (NPs) encapsidate the genomic RNA into nucleocapsids, which are then incorporated into virus particles. We determined the protein-protein interaction between NP molecules and the molecular mechanism required for incorporating nucleocapsids into virions in two closely related viruses, human parainfluenza virus type 1 (hPIV1) and Sendai virus (SV). Expression of NP from cDNA resulted in in vivo nucleocapsid formation. Electron micrographs showed no significant difference in the morphological appearance of viral nucleocapsids obtained from lysates of transfected cells expressing SV or hPIVI NP cDNA. Coexpression of NP cDNAs from both viruses resulted in the formation of nucleocapsid composed of a mixture of NP molecules; thus, the NPs of both viruses contained regions that allowed the formation of mixed nucleocapsid. Mixed nucleocapsids were also detected in cells infected with SV and transfected with hPIV1 NP cDNA. However, when NP of SV was donated by infected virus and hPIV1 NP was from transfected cDNA, nucleocapsids composed of NPs solely from SV or solely from hPIVI were also detected. Although almost equal amounts of NP of the two viruses were found in the cytoplasm of cells infected with SV and transfected with hPIV1 NP cDNA, 90% of the NPs in the nucleocapsids of the progeny SV virions were from SV. Thus, nucleocapsids containing heterologous hPIV1 NPs were excluded during the assembly of progeny SV virions. Coexpression of hPIV1 NP and hPIV1 matrix protein (M) in SV-infected cells increased the uptake of nucleocapsids containing hPIV1 NP; thus, M appears to be responsible for the specific incorporation of the nucleocapsid into virions. Using SV-hPIV1 chimera NP cDNAs, we found that the C-terminal domain of the NP protein (amino acids 420 to 466) is responsible for the interaction with M." @default.
• W2003158984 created "2016-06-24" @default.
• W2003158984 creator A5000860874 @default.
• W2003158984 creator A5039769164 @default.
• W2003158984 creator A5048208412 @default.
• W2003158984 creator A5058677505 @default.
• W2003158984 creator A5062986426 @default.
• W2003158984 date "2001-02-01" @default.
• W2003158984 modified "2023-10-18" @default.
• W2003158984 title "Nucleocapsid Incorporation into Parainfluenza Virus Is Regulated by Specific Interaction with Matrix Protein" @default.
• W2003158984 cites W1483177484 @default.
• W2003158984 cites W1530867604 @default.
• W2003158984 cites W1590027774 @default.
• W2003158984 cites W1605220975 @default.
• W2003158984 cites W1621854464 @default.
• W2003158984 cites W1775741884 @default.
• W2003158984 cites W1784291848 @default.
• W2003158984 cites W1864016576 @default.
• W2003158984 cites W1905739540 @default.
• W2003158984 cites W1965831445 @default.
• W2003158984 cites W1979859237 @default.
• W2003158984 cites W1980971855 @default.
• W2003158984 cites W1981246496 @default.
• W2003158984 cites W1998591058 @default.
• W2003158984 cites W2001382548 @default.
• W2003158984 cites W2007859256 @default.
• W2003158984 cites W2011729478 @default.
• W2003158984 cites W2048162805 @default.
• W2003158984 cites W2062241081 @default.
• W2003158984 cites W2106650051 @default.
• W2003158984 cites W2124978422 @default.
• W2003158984 cites W2127747050 @default.
• W2003158984 cites W2130300740 @default.
• W2003158984 cites W2144164843 @default.
• W2003158984 cites W2153911225 @default.
• W2003158984 cites W2165918134 @default.
• W2003158984 cites W4243432010 @default.
• W2003158984 cites W72594013 @default.
• W2003158984 doi "https://doi.org/10.1128/jvi.75.3.1117-1123.2001" @default.
• W2003158984 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/114017" @default.
• W2003158984 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11152484" @default.
• W2003158984 hasPublicationYear "2001" @default.
• W2003158984 type Work @default.
• W2003158984 sameAs 2003158984 @default.
• W2003158984 citedByCount "86" @default.
• W2003158984 countsByYear W20031589842013 @default.
• W2003158984 countsByYear W20031589842014 @default.
• W2003158984 countsByYear W20031589842015 @default.
• W2003158984 countsByYear W20031589842016 @default.
• W2003158984 countsByYear W20031589842017 @default.
• W2003158984 countsByYear W20031589842018 @default.
• W2003158984 countsByYear W20031589842020 @default.
• W2003158984 countsByYear W20031589842021 @default.
• W2003158984 countsByYear W20031589842022 @default.
• W2003158984 countsByYear W20031589842023 @default.
• W2003158984 crossrefType "journal-article" @default.
• W2003158984 hasAuthorship W2003158984A5000860874 @default.
• W2003158984 hasAuthorship W2003158984A5039769164 @default.
• W2003158984 hasAuthorship W2003158984A5048208412 @default.
• W2003158984 hasAuthorship W2003158984A5058677505 @default.
• W2003158984 hasAuthorship W2003158984A5062986426 @default.
• W2003158984 hasBestOaLocation W20031589841 @default.
• W2003158984 hasConcept C104317684 @default.
• W2003158984 hasConcept C153911025 @default.
• W2003158984 hasConcept C159047783 @default.
• W2003158984 hasConcept C187882448 @default.
• W2003158984 hasConcept C190062978 @default.
• W2003158984 hasConcept C2522874641 @default.
• W2003158984 hasConcept C2780115692 @default.
• W2003158984 hasConcept C2780127873 @default.
• W2003158984 hasConcept C54009773 @default.
• W2003158984 hasConcept C54355233 @default.
• W2003158984 hasConcept C55493867 @default.
• W2003158984 hasConcept C60325843 @default.
• W2003158984 hasConcept C68434959 @default.
• W2003158984 hasConcept C81885089 @default.
• W2003158984 hasConcept C86803240 @default.
• W2003158984 hasConcept C95444343 @default.
• W2003158984 hasConceptScore W2003158984C104317684 @default.
• W2003158984 hasConceptScore W2003158984C153911025 @default.
• W2003158984 hasConceptScore W2003158984C159047783 @default.
• W2003158984 hasConceptScore W2003158984C187882448 @default.
• W2003158984 hasConceptScore W2003158984C190062978 @default.
• W2003158984 hasConceptScore W2003158984C2522874641 @default.
• W2003158984 hasConceptScore W2003158984C2780115692 @default.
• W2003158984 hasConceptScore W2003158984C2780127873 @default.
• W2003158984 hasConceptScore W2003158984C54009773 @default.
• W2003158984 hasConceptScore W2003158984C54355233 @default.
• W2003158984 hasConceptScore W2003158984C55493867 @default.
• W2003158984 hasConceptScore W2003158984C60325843 @default.
• W2003158984 hasConceptScore W2003158984C68434959 @default.
• W2003158984 hasConceptScore W2003158984C81885089 @default.
• W2003158984 hasConceptScore W2003158984C86803240 @default.
• W2003158984 hasConceptScore W2003158984C95444343 @default.
• W2003158984 hasIssue "3" @default.
• W2003158984 hasLocation W20031589841 @default.
• W2003158984 hasLocation W20031589842 @default.
• W2003158984 hasLocation W20031589843 @default.

• next