FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003161706> ?p ?o ?g. }

• W2003161706 endingPage "53" @default.
• W2003161706 startingPage "48" @default.
• W2003161706 abstract "Although KIT and EGFR overexpressions are reported to occur in breast cancer, their pathological significance is still unclear. We examined KIT, EGFR, and c-erbB-2 overexpressions immunohistochemically in 150 cases of surgically resected breast cancer and their correlation with the histological type and grade and mesenchymal and/or myoepithelial immunophenotype of primary tumors. To facilitate the analysis, we constructed a tissue microarray comprising 2-mm diameter tissues cored from the representative tissue block of each tumor. KIT, EGFR, and c-erbB-2 overexpressions were detected in 15 (10%), 12 (8%), and 23 (15%), respectively. The KIT was more frequent in the group comprising comedo-type ductal carcinoma in situ and invasive ductal carcinomas (IDCs) of the solid-tubular subtype than in the group of other histological types (P=0.027), and the EGFR was more frequent in IDCs of solid-tubular type than in other histological types (P <0.05). KIT and EGFR overexpressions were correlated with nuclear grade 3 (P=0.0095 and 0.0005) and tended to be concurrent (P=0.005). KIT overexpression was correlated with vimentin and S-100 expression (P=0.003 and P=0.005), and EGFR overexpression was correlated with S100 expression (P=0.0001). These correlations with grade and mesenchymal/myoepithelial markers were not observed for c-erbB-2 overexpression. KIT and EGFR appeared to be indicators of high-grade breast carcinoma groups that often contain the carcinomas with mesenchymal and/or myoepithelial differentiation, which are distinct from the group with c-erbB-2 overexpression." @default.
• W2003161706 created "2016-06-24" @default.
• W2003161706 creator A5011856157 @default.
• W2003161706 creator A5015825703 @default.
• W2003161706 creator A5018706370 @default.
• W2003161706 creator A5051249520 @default.
• W2003161706 creator A5056887722 @default.
• W2003161706 creator A5057738520 @default.
• W2003161706 creator A5063851467 @default.
• W2003161706 creator A5065736621 @default.
• W2003161706 creator A5077662682 @default.
• W2003161706 creator A5082836616 @default.
• W2003161706 creator A5090051808 @default.
• W2003161706 date "2005-01-01" @default.
• W2003161706 modified "2023-10-15" @default.
• W2003161706 title "Correlation of KIT and EGFR overexpression with invasive ductal breast carcinoma of the solid-tubular subtype, nuclear grade 3, and mesenchymal or myoepithelial differentiation" @default.
• W2003161706 cites W1752312133 @default.
• W2003161706 cites W1967252809 @default.
• W2003161706 cites W1975879668 @default.
• W2003161706 cites W1977992852 @default.
• W2003161706 cites W1988561129 @default.
• W2003161706 cites W2002842378 @default.
• W2003161706 cites W2015015957 @default.
• W2003161706 cites W2020066255 @default.
• W2003161706 cites W2023660230 @default.
• W2003161706 cites W2043530704 @default.
• W2003161706 cites W2052882948 @default.
• W2003161706 cites W2054961739 @default.
• W2003161706 cites W2058070604 @default.
• W2003161706 cites W2062066667 @default.
• W2003161706 cites W2071763005 @default.
• W2003161706 cites W2078159546 @default.
• W2003161706 cites W2085880972 @default.
• W2003161706 cites W2087810003 @default.
• W2003161706 cites W2103774582 @default.
• W2003161706 cites W2122445130 @default.
• W2003161706 cites W2150501295 @default.
• W2003161706 cites W2164777277 @default.
• W2003161706 cites W2165677013 @default.
• W2003161706 cites W2165720262 @default.
• W2003161706 cites W2171620774 @default.
• W2003161706 cites W2329648702 @default.
• W2003161706 cites W4241370600 @default.
• W2003161706 doi "https://doi.org/10.1111/j.1349-7006.2005.00009.x" @default.
• W2003161706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15649255" @default.
• W2003161706 hasPublicationYear "2005" @default.
• W2003161706 type Work @default.
• W2003161706 sameAs 2003161706 @default.
• W2003161706 citedByCount "65" @default.
• W2003161706 countsByYear W20031617062012 @default.
• W2003161706 countsByYear W20031617062013 @default.
• W2003161706 countsByYear W20031617062014 @default.
• W2003161706 countsByYear W20031617062015 @default.
• W2003161706 countsByYear W20031617062016 @default.
• W2003161706 countsByYear W20031617062017 @default.
• W2003161706 countsByYear W20031617062020 @default.
• W2003161706 countsByYear W20031617062022 @default.
• W2003161706 crossrefType "journal-article" @default.
• W2003161706 hasAuthorship W2003161706A5011856157 @default.
• W2003161706 hasAuthorship W2003161706A5015825703 @default.
• W2003161706 hasAuthorship W2003161706A5018706370 @default.
• W2003161706 hasAuthorship W2003161706A5051249520 @default.
• W2003161706 hasAuthorship W2003161706A5056887722 @default.
• W2003161706 hasAuthorship W2003161706A5057738520 @default.
• W2003161706 hasAuthorship W2003161706A5063851467 @default.
• W2003161706 hasAuthorship W2003161706A5065736621 @default.
• W2003161706 hasAuthorship W2003161706A5077662682 @default.
• W2003161706 hasAuthorship W2003161706A5082836616 @default.
• W2003161706 hasAuthorship W2003161706A5090051808 @default.
• W2003161706 hasBestOaLocation W20031617061 @default.
• W2003161706 hasConcept C121608353 @default.
• W2003161706 hasConcept C126322002 @default.
• W2003161706 hasConcept C140884156 @default.
• W2003161706 hasConcept C142724271 @default.
• W2003161706 hasConcept C147447768 @default.
• W2003161706 hasConcept C193270364 @default.
• W2003161706 hasConcept C198826908 @default.
• W2003161706 hasConcept C204232928 @default.
• W2003161706 hasConcept C2777546739 @default.
• W2003161706 hasConcept C2780045663 @default.
• W2003161706 hasConcept C2780862961 @default.
• W2003161706 hasConcept C502942594 @default.
• W2003161706 hasConcept C530470458 @default.
• W2003161706 hasConcept C71924100 @default.
• W2003161706 hasConcept C86803240 @default.
• W2003161706 hasConceptScore W2003161706C121608353 @default.
• W2003161706 hasConceptScore W2003161706C126322002 @default.
• W2003161706 hasConceptScore W2003161706C140884156 @default.
• W2003161706 hasConceptScore W2003161706C142724271 @default.
• W2003161706 hasConceptScore W2003161706C147447768 @default.
• W2003161706 hasConceptScore W2003161706C193270364 @default.
• W2003161706 hasConceptScore W2003161706C198826908 @default.
• W2003161706 hasConceptScore W2003161706C204232928 @default.
• W2003161706 hasConceptScore W2003161706C2777546739 @default.
• W2003161706 hasConceptScore W2003161706C2780045663 @default.
• W2003161706 hasConceptScore W2003161706C2780862961 @default.
• W2003161706 hasConceptScore W2003161706C502942594 @default.
• W2003161706 hasConceptScore W2003161706C530470458 @default.

• next