Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003169090> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2003169090 endingPage "424" @default.
- W2003169090 startingPage "421" @default.
- W2003169090 abstract "Antineutrophil cytoplasmic antibodies (ANCA) are of established value in the diagnosis of Wegener's granulomatosis allowing early introduction of therapy. These patients are at risk of opportunistic infection, especially whilst receiving immunosuppressive drugs and this may mimic reactivation of disease. We present three cases of Wegener's granulomatosis complicated by opportunistic infection and assess the value of ANCA detection. Two presented with symptoms compatible with disease reactivation but ANCA were negative. One died with pulmonary infection due to Pneumocystis carinii, Aspergillus fumigatus and Herpes simplex. Transbronchial biopsy in the second case revealed Pneumocystis carinii. A third case had strongly positive serum ANCA at diagnosis but in addition pulmonary infection with Legionella pneumophila. ANCA detection is of value in patients with Wegener's granulomatosis, but the result must be interpreted in the full clinical context. Antineutrophil cytoplasmic antibodies (ANCA) are of established value in the diagnosis of Wegener's granulomatosis allowing early introduction of therapy. These patients are at risk of opportunistic infection, especially whilst receiving immunosuppressive drugs and this may mimic reactivation of disease. We present three cases of Wegener's granulomatosis complicated by opportunistic infection and assess the value of ANCA detection. Two presented with symptoms compatible with disease reactivation but ANCA were negative. One died with pulmonary infection due to Pneumocystis carinii, Aspergillus fumigatus and Herpes simplex. Transbronchial biopsy in the second case revealed Pneumocystis carinii. A third case had strongly positive serum ANCA at diagnosis but in addition pulmonary infection with Legionella pneumophila. ANCA detection is of value in patients with Wegener's granulomatosis, but the result must be interpreted in the full clinical context." @default.
- W2003169090 created "2016-06-24" @default.
- W2003169090 creator A5061618799 @default.
- W2003169090 creator A5063219336 @default.
- W2003169090 date "1989-01-01" @default.
- W2003169090 modified "2023-09-25" @default.
- W2003169090 title "Opportunistic infection and antineutrophil cytoplasm antibodies in Wegener's granulomatosis" @default.
- W2003169090 cites W1982860902 @default.
- W2003169090 cites W1985948325 @default.
- W2003169090 cites W2010514872 @default.
- W2003169090 cites W2061515304 @default.
- W2003169090 cites W2091746620 @default.
- W2003169090 cites W2162725007 @default.
- W2003169090 doi "https://doi.org/10.1016/s0954-6111(89)80074-5" @default.
- W2003169090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2616825" @default.
- W2003169090 hasPublicationYear "1989" @default.
- W2003169090 type Work @default.
- W2003169090 sameAs 2003169090 @default.
- W2003169090 citedByCount "6" @default.
- W2003169090 crossrefType "journal-article" @default.
- W2003169090 hasAuthorship W2003169090A5061618799 @default.
- W2003169090 hasAuthorship W2003169090A5063219336 @default.
- W2003169090 hasConcept C142724271 @default.
- W2003169090 hasConcept C203014093 @default.
- W2003169090 hasConcept C24040308 @default.
- W2003169090 hasConcept C2776015282 @default.
- W2003169090 hasConcept C2776118409 @default.
- W2003169090 hasConcept C2777559004 @default.
- W2003169090 hasConcept C2779134260 @default.
- W2003169090 hasConcept C2779164008 @default.
- W2003169090 hasConcept C2779196057 @default.
- W2003169090 hasConcept C2779787849 @default.
- W2003169090 hasConcept C2780727368 @default.
- W2003169090 hasConcept C2993443204 @default.
- W2003169090 hasConcept C3013748606 @default.
- W2003169090 hasConcept C523546767 @default.
- W2003169090 hasConcept C54355233 @default.
- W2003169090 hasConcept C71924100 @default.
- W2003169090 hasConcept C86803240 @default.
- W2003169090 hasConceptScore W2003169090C142724271 @default.
- W2003169090 hasConceptScore W2003169090C203014093 @default.
- W2003169090 hasConceptScore W2003169090C24040308 @default.
- W2003169090 hasConceptScore W2003169090C2776015282 @default.
- W2003169090 hasConceptScore W2003169090C2776118409 @default.
- W2003169090 hasConceptScore W2003169090C2777559004 @default.
- W2003169090 hasConceptScore W2003169090C2779134260 @default.
- W2003169090 hasConceptScore W2003169090C2779164008 @default.
- W2003169090 hasConceptScore W2003169090C2779196057 @default.
- W2003169090 hasConceptScore W2003169090C2779787849 @default.
- W2003169090 hasConceptScore W2003169090C2780727368 @default.
- W2003169090 hasConceptScore W2003169090C2993443204 @default.
- W2003169090 hasConceptScore W2003169090C3013748606 @default.
- W2003169090 hasConceptScore W2003169090C523546767 @default.
- W2003169090 hasConceptScore W2003169090C54355233 @default.
- W2003169090 hasConceptScore W2003169090C71924100 @default.
- W2003169090 hasConceptScore W2003169090C86803240 @default.
- W2003169090 hasIssue "5" @default.
- W2003169090 hasLocation W20031690901 @default.
- W2003169090 hasLocation W20031690902 @default.
- W2003169090 hasOpenAccess W2003169090 @default.
- W2003169090 hasPrimaryLocation W20031690901 @default.
- W2003169090 hasRelatedWork W1528484476 @default.
- W2003169090 hasRelatedWork W180838512 @default.
- W2003169090 hasRelatedWork W1973357051 @default.
- W2003169090 hasRelatedWork W2003169090 @default.
- W2003169090 hasRelatedWork W2011792783 @default.
- W2003169090 hasRelatedWork W208354062 @default.
- W2003169090 hasRelatedWork W2123029256 @default.
- W2003169090 hasRelatedWork W2422454297 @default.
- W2003169090 hasRelatedWork W2434125128 @default.
- W2003169090 hasRelatedWork W2512168211 @default.
- W2003169090 hasVolume "83" @default.
- W2003169090 isParatext "false" @default.
- W2003169090 isRetracted "false" @default.
- W2003169090 magId "2003169090" @default.
- W2003169090 workType "article" @default.