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- W2003172326 abstract "A green and efficient method is described for the solvent free synthesis of 3,4-dihydropyrimidin-2(1H)-ones through one-pot three-component condensation of ethyl acetoacetate, an aryl aldehyde, and urea using mesoporous MCM-41 supported ammonium dihydrogen phosphate (NH4H2PO4/MCM-41) as catalyst. The present methodology offers several advantages such as high yields, relatively short reaction times, mild reaction condition, easy work up, and using a highly recyclable catalyst. Some mechanistic studies revealed that the reaction would be achieved via formation of an acyliminium ion, followed by an acid-catalyzed cyclodehydration step." @default.
- W2003172326 created "2016-06-24" @default.
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- W2003172326 date "2017-02-01" @default.
- W2003172326 modified "2023-10-11" @default.
- W2003172326 title "Solvent free one-pot multi-component synthesis of 3,4-dihydropyrimidin-2(1 H )-ones catalyzed by mesoporous NH 4 H 2 PO 4 /MCM-41 as an environmentally friendly, cheap, and effective catalyst" @default.
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- W2003172326 doi "https://doi.org/10.1016/j.arabjc.2012.12.001" @default.
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