Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003173217> ?p ?o ?g. }
- W2003173217 endingPage "8890" @default.
- W2003173217 startingPage "8884" @default.
- W2003173217 abstract "Relationships of electrostatic interaction and encapsulation between poly(amidoamine) (PAMAM) dendrimers and negatively charged drug molecules have been investigated by aqueous solubility and NMR ( (1)H NMR and two-dimensional nuclear Overhauser effect spectroscopy (2D-NOESY)) studies. PAMAM dendrimers significantly increased the solubilities of phenobarbital and sulfamethoxazole, but scarcely influenced those of primidone and trimethoprim. Moreover, (1)H NMR and 2D-NOESY measurements indicated that few phenobarbital or sulfamethoxazole molecules were entrapped in the cavities of low-generation dendrimers (generation 3, G3). These results suggest that external electrostatic interaction contributes more to the solubility enhancement of drugs than internal encapsulation." @default.
- W2003173217 created "2016-06-24" @default.
- W2003173217 creator A5011788131 @default.
- W2003173217 creator A5020228335 @default.
- W2003173217 creator A5031524996 @default.
- W2003173217 creator A5070973341 @default.
- W2003173217 date "2008-07-01" @default.
- W2003173217 modified "2023-09-30" @default.
- W2003173217 title "External Electrostatic Interaction versus Internal Encapsulation between Cationic Dendrimers and Negatively Charged Drugs: Which Contributes More to Solubility Enhancement of the Drugs?" @default.
- W2003173217 cites W1965800158 @default.
- W2003173217 cites W1968218788 @default.
- W2003173217 cites W1968798927 @default.
- W2003173217 cites W1974055831 @default.
- W2003173217 cites W1974439732 @default.
- W2003173217 cites W1978223966 @default.
- W2003173217 cites W1980627211 @default.
- W2003173217 cites W1983964958 @default.
- W2003173217 cites W1985922065 @default.
- W2003173217 cites W2002338306 @default.
- W2003173217 cites W2006682004 @default.
- W2003173217 cites W2009500363 @default.
- W2003173217 cites W2010729053 @default.
- W2003173217 cites W2012758455 @default.
- W2003173217 cites W2013875806 @default.
- W2003173217 cites W2020373947 @default.
- W2003173217 cites W2024659370 @default.
- W2003173217 cites W2030218248 @default.
- W2003173217 cites W2030979932 @default.
- W2003173217 cites W2044158732 @default.
- W2003173217 cites W2063786258 @default.
- W2003173217 cites W2069131793 @default.
- W2003173217 cites W2072952339 @default.
- W2003173217 cites W2080574092 @default.
- W2003173217 cites W2080643197 @default.
- W2003173217 cites W2080823739 @default.
- W2003173217 cites W2082904634 @default.
- W2003173217 cites W2091244484 @default.
- W2003173217 cites W2095122176 @default.
- W2003173217 cites W2096503457 @default.
- W2003173217 cites W2097007428 @default.
- W2003173217 cites W2098260391 @default.
- W2003173217 cites W2102453083 @default.
- W2003173217 cites W2103882716 @default.
- W2003173217 cites W2111629830 @default.
- W2003173217 cites W2121360740 @default.
- W2003173217 cites W2137302260 @default.
- W2003173217 cites W2138180304 @default.
- W2003173217 cites W2144319700 @default.
- W2003173217 cites W2145010618 @default.
- W2003173217 cites W2154033456 @default.
- W2003173217 cites W2161051270 @default.
- W2003173217 cites W2163294691 @default.
- W2003173217 cites W2164425035 @default.
- W2003173217 cites W2167385903 @default.
- W2003173217 cites W2170396812 @default.
- W2003173217 cites W4253635591 @default.
- W2003173217 doi "https://doi.org/10.1021/jp801742t" @default.
- W2003173217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18605754" @default.
- W2003173217 hasPublicationYear "2008" @default.
- W2003173217 type Work @default.
- W2003173217 sameAs 2003173217 @default.
- W2003173217 citedByCount "85" @default.
- W2003173217 countsByYear W20031732172012 @default.
- W2003173217 countsByYear W20031732172013 @default.
- W2003173217 countsByYear W20031732172014 @default.
- W2003173217 countsByYear W20031732172015 @default.
- W2003173217 countsByYear W20031732172016 @default.
- W2003173217 countsByYear W20031732172017 @default.
- W2003173217 countsByYear W20031732172018 @default.
- W2003173217 countsByYear W20031732172019 @default.
- W2003173217 countsByYear W20031732172021 @default.
- W2003173217 countsByYear W20031732172022 @default.
- W2003173217 countsByYear W20031732172023 @default.
- W2003173217 crossrefType "journal-article" @default.
- W2003173217 hasAuthorship W2003173217A5011788131 @default.
- W2003173217 hasAuthorship W2003173217A5020228335 @default.
- W2003173217 hasAuthorship W2003173217A5031524996 @default.
- W2003173217 hasAuthorship W2003173217A5070973341 @default.
- W2003173217 hasConcept C103319777 @default.
- W2003173217 hasConcept C119851462 @default.
- W2003173217 hasConcept C155574463 @default.
- W2003173217 hasConcept C159467904 @default.
- W2003173217 hasConcept C178790620 @default.
- W2003173217 hasConcept C184651966 @default.
- W2003173217 hasConcept C185592680 @default.
- W2003173217 hasConcept C19549132 @default.
- W2003173217 hasConcept C2982804355 @default.
- W2003173217 hasConcept C32909587 @default.
- W2003173217 hasConcept C55637122 @default.
- W2003173217 hasConcept C66974803 @default.
- W2003173217 hasConcept C71240020 @default.
- W2003173217 hasConceptScore W2003173217C103319777 @default.
- W2003173217 hasConceptScore W2003173217C119851462 @default.
- W2003173217 hasConceptScore W2003173217C155574463 @default.
- W2003173217 hasConceptScore W2003173217C159467904 @default.
- W2003173217 hasConceptScore W2003173217C178790620 @default.
- W2003173217 hasConceptScore W2003173217C184651966 @default.
- W2003173217 hasConceptScore W2003173217C185592680 @default.