FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003178269> ?p ?o ?g. }

• W2003178269 endingPage "961" @default.
• W2003178269 startingPage "950" @default.
• W2003178269 abstract "Mannose binding lectin (MBL) is a pattern recognition molecule that plays a pivotal role in innate immunity. This liver derived, circulating plasma protein binds organisms displaying high-density carbohydrate structures and flags them for destruction via opsonisation and initiation of the lectin pathway of the complement cascade. The present study reveals native, oligomeric forms of human MBL in plasma from healthy blood donors of differing genotypes and correlates the relative abundance of observed molecular weight species with mannan binding activity and C4 deposition in vitro. Wild type (A/A) individuals demonstrate predominately high molecular weight MBL that correlated with high mannan binding capacity and C4 deposition. A/C individuals demonstrated predominantly low molecular weight MBL with decreased mannan binding and C4 deposition activity. A/D individuals demonstrated both high molecular weight and low molecular weight MBL with reduced mannan binding and C4 deposition predominantly seen in combination with LX promoter. We identified A/B individuals as a unique group with large variation in MBL level, mannan binding activity and C4 deposition and propose a model for C4 deposition based on differential binding of MASP." @default.
• W2003178269 created "2016-06-24" @default.
• W2003178269 creator A5009176458 @default.
• W2003178269 creator A5012090839 @default.
• W2003178269 creator A5068465959 @default.
• W2003178269 date "2006-03-01" @default.
• W2003178269 modified "2023-10-18" @default.
• W2003178269 title "Heteroligomeric forms of codon 54 mannose binding lectin (MBL) in circulation demonstrate reduced in vitro function" @default.
• W2003178269 cites W1512118356 @default.
• W2003178269 cites W1606330082 @default.
• W2003178269 cites W1648429623 @default.
• W2003178269 cites W1911746360 @default.
• W2003178269 cites W1965036756 @default.
• W2003178269 cites W1978567121 @default.
• W2003178269 cites W1983791133 @default.
• W2003178269 cites W1987308877 @default.
• W2003178269 cites W1991163875 @default.
• W2003178269 cites W1991661108 @default.
• W2003178269 cites W1992830524 @default.
• W2003178269 cites W1993225710 @default.
• W2003178269 cites W1998211475 @default.
• W2003178269 cites W2002178602 @default.
• W2003178269 cites W2021074141 @default.
• W2003178269 cites W2031433110 @default.
• W2003178269 cites W2033631197 @default.
• W2003178269 cites W2040737232 @default.
• W2003178269 cites W2046605974 @default.
• W2003178269 cites W2047233465 @default.
• W2003178269 cites W2049425159 @default.
• W2003178269 cites W2051718508 @default.
• W2003178269 cites W2070980909 @default.
• W2003178269 cites W2073503811 @default.
• W2003178269 cites W2077008485 @default.
• W2003178269 cites W2079447585 @default.
• W2003178269 cites W2082622645 @default.
• W2003178269 cites W2086382677 @default.
• W2003178269 cites W2100837269 @default.
• W2003178269 cites W2105269353 @default.
• W2003178269 cites W2118094160 @default.
• W2003178269 cites W2119423436 @default.
• W2003178269 cites W2119799948 @default.
• W2003178269 cites W2123539140 @default.
• W2003178269 cites W2126261381 @default.
• W2003178269 cites W2131085727 @default.
• W2003178269 cites W2140881670 @default.
• W2003178269 cites W2151977739 @default.
• W2003178269 cites W2164969570 @default.
• W2003178269 cites W2165703844 @default.
• W2003178269 cites W2167874765 @default.
• W2003178269 cites W2301989161 @default.
• W2003178269 cites W2304032484 @default.
• W2003178269 cites W4238718244 @default.
• W2003178269 doi "https://doi.org/10.1016/j.molimm.2005.06.023" @default.
• W2003178269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16099048" @default.
• W2003178269 hasPublicationYear "2006" @default.
• W2003178269 type Work @default.
• W2003178269 sameAs 2003178269 @default.
• W2003178269 citedByCount "26" @default.
• W2003178269 countsByYear W20031782692012 @default.
• W2003178269 countsByYear W20031782692013 @default.
• W2003178269 countsByYear W20031782692014 @default.
• W2003178269 countsByYear W20031782692016 @default.
• W2003178269 countsByYear W20031782692018 @default.
• W2003178269 countsByYear W20031782692021 @default.
• W2003178269 countsByYear W20031782692022 @default.
• W2003178269 crossrefType "journal-article" @default.
• W2003178269 hasAuthorship W2003178269A5009176458 @default.
• W2003178269 hasAuthorship W2003178269A5012090839 @default.
• W2003178269 hasAuthorship W2003178269A5068465959 @default.
• W2003178269 hasConcept C100817775 @default.
• W2003178269 hasConcept C111684460 @default.
• W2003178269 hasConcept C133493029 @default.
• W2003178269 hasConcept C136449434 @default.
• W2003178269 hasConcept C159654299 @default.
• W2003178269 hasConcept C170493617 @default.
• W2003178269 hasConcept C171279029 @default.
• W2003178269 hasConcept C185592680 @default.
• W2003178269 hasConcept C189413060 @default.
• W2003178269 hasConcept C202751555 @default.
• W2003178269 hasConcept C203014093 @default.
• W2003178269 hasConcept C203880312 @default.
• W2003178269 hasConcept C2775887612 @default.
• W2003178269 hasConcept C2779719659 @default.
• W2003178269 hasConcept C2780758401 @default.
• W2003178269 hasConcept C55493867 @default.
• W2003178269 hasConcept C86803240 @default.
• W2003178269 hasConceptScore W2003178269C100817775 @default.
• W2003178269 hasConceptScore W2003178269C111684460 @default.
• W2003178269 hasConceptScore W2003178269C133493029 @default.
• W2003178269 hasConceptScore W2003178269C136449434 @default.
• W2003178269 hasConceptScore W2003178269C159654299 @default.
• W2003178269 hasConceptScore W2003178269C170493617 @default.
• W2003178269 hasConceptScore W2003178269C171279029 @default.
• W2003178269 hasConceptScore W2003178269C185592680 @default.
• W2003178269 hasConceptScore W2003178269C189413060 @default.
• W2003178269 hasConceptScore W2003178269C202751555 @default.
• W2003178269 hasConceptScore W2003178269C203014093 @default.
• W2003178269 hasConceptScore W2003178269C203880312 @default.

• next