FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003183205> ?p ?o ?g. }

• W2003183205 endingPage "152" @default.
• W2003183205 startingPage "145" @default.
• W2003183205 abstract "Smoking during pregnancy is associated with a variety of untoward effects on the offspring. However, recent epidemiological studies have brought into question whether the association between neurobehavioral deficits and maternal smoking is causal. We utilized an animal model of maternal smoking to determine the effects of prenatal cigarette smoke (CS) exposure on neurobehavioral development. Pregnant mice were exposed to either filtered air or mainstream CS from gestation day (GD) 4 to parturition for 4 h/d and 5 d/wk, with each exposure producing maternal plasma concentration of cotinine equivalent to smoking < 1 pack of cigarettes per day (25 ng/ml plasma cotinine level). Pups were weaned at postnatal day (PND) 21 and behavior was assessed at 4 weeks of age and again at 4–6 months of age. Male, but not female, offspring of CS-exposed dams demonstrated a significant increase in locomotor activity during adolescence and adulthood that was ameliorated by methylphenidate treatment. Additionally, male offspring exhibited increased aggression, as evidenced by decreased latency to attack and number of attacks in a resident–intruder task. These behavioral abnormalities were accompanied by a significant decrease in striatal and cortical dopamine and serotonin and a significant reduction in brain-derived neurotrophic factor (BDNF) mRNA and protein. Taken in concert, these data demonstrate that prenatal exposure to CS produces behavioral alterations in mice that are similar to those observed in epidemiological studies linking maternal smoking to neurodevelopmental disorders. Further, these data also suggest a role for monaminergic and BDNF alterations in these effects." @default.
• W2003183205 created "2016-06-24" @default.
• W2003183205 creator A5006392947 @default.
• W2003183205 creator A5014310365 @default.
• W2003183205 creator A5014890619 @default.
• W2003183205 creator A5021586993 @default.
• W2003183205 creator A5045586758 @default.
• W2003183205 creator A5064838071 @default.
• W2003183205 date "2014-04-01" @default.
• W2003183205 modified "2023-10-18" @default.
• W2003183205 title "Prenatal cigarette smoke exposure causes hyperactivity and aggressive behavior: Role of altered catecholamines and BDNF" @default.
• W2003183205 cites W138330660 @default.
• W2003183205 cites W1821549704 @default.
• W2003183205 cites W1975955158 @default.
• W2003183205 cites W1977882100 @default.
• W2003183205 cites W1979665818 @default.
• W2003183205 cites W1984719574 @default.
• W2003183205 cites W1985926091 @default.
• W2003183205 cites W1991387438 @default.
• W2003183205 cites W1994386017 @default.
• W2003183205 cites W1995686738 @default.
• W2003183205 cites W1996514137 @default.
• W2003183205 cites W2000996401 @default.
• W2003183205 cites W2012597831 @default.
• W2003183205 cites W2022650589 @default.
• W2003183205 cites W2026920992 @default.
• W2003183205 cites W2027221598 @default.
• W2003183205 cites W2027373187 @default.
• W2003183205 cites W2028198895 @default.
• W2003183205 cites W2039198521 @default.
• W2003183205 cites W2041149034 @default.
• W2003183205 cites W2041588721 @default.
• W2003183205 cites W2041868785 @default.
• W2003183205 cites W2056863404 @default.
• W2003183205 cites W2058338512 @default.
• W2003183205 cites W2068145071 @default.
• W2003183205 cites W2069626958 @default.
• W2003183205 cites W2070058327 @default.
• W2003183205 cites W2076361777 @default.
• W2003183205 cites W2079834554 @default.
• W2003183205 cites W2083311350 @default.
• W2003183205 cites W2087968778 @default.
• W2003183205 cites W2091099857 @default.
• W2003183205 cites W2092571202 @default.
• W2003183205 cites W2092594981 @default.
• W2003183205 cites W2093600607 @default.
• W2003183205 cites W2094191238 @default.
• W2003183205 cites W2100012493 @default.
• W2003183205 cites W2105056806 @default.
• W2003183205 cites W2112041738 @default.
• W2003183205 cites W2123018620 @default.
• W2003183205 cites W2125347442 @default.
• W2003183205 cites W2128888401 @default.
• W2003183205 cites W2132879496 @default.
• W2003183205 cites W2137701794 @default.
• W2003183205 cites W2139334238 @default.
• W2003183205 cites W2144696336 @default.
• W2003183205 cites W2145901562 @default.
• W2003183205 cites W2156813023 @default.
• W2003183205 cites W2158418624 @default.
• W2003183205 cites W2159692236 @default.
• W2003183205 cites W2167318273 @default.
• W2003183205 cites W2171162608 @default.
• W2003183205 cites W2172206033 @default.
• W2003183205 cites W2312531030 @default.
• W2003183205 cites W5314447 @default.
• W2003183205 doi "https://doi.org/10.1016/j.expneurol.2014.01.016" @default.
• W2003183205 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3982151" @default.
• W2003183205 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24486851" @default.
• W2003183205 hasPublicationYear "2014" @default.
• W2003183205 type Work @default.
• W2003183205 sameAs 2003183205 @default.
• W2003183205 citedByCount "69" @default.
• W2003183205 countsByYear W20031832052014 @default.
• W2003183205 countsByYear W20031832052015 @default.
• W2003183205 countsByYear W20031832052016 @default.
• W2003183205 countsByYear W20031832052017 @default.
• W2003183205 countsByYear W20031832052018 @default.
• W2003183205 countsByYear W20031832052019 @default.
• W2003183205 countsByYear W20031832052020 @default.
• W2003183205 countsByYear W20031832052021 @default.
• W2003183205 countsByYear W20031832052022 @default.
• W2003183205 countsByYear W20031832052023 @default.
• W2003183205 crossrefType "journal-article" @default.
• W2003183205 hasAuthorship W2003183205A5006392947 @default.
• W2003183205 hasAuthorship W2003183205A5014310365 @default.
• W2003183205 hasAuthorship W2003183205A5014890619 @default.
• W2003183205 hasAuthorship W2003183205A5021586993 @default.
• W2003183205 hasAuthorship W2003183205A5045586758 @default.
• W2003183205 hasAuthorship W2003183205A5064838071 @default.
• W2003183205 hasBestOaLocation W20031832052 @default.
• W2003183205 hasConcept C112672928 @default.
• W2003183205 hasConcept C126322002 @default.
• W2003183205 hasConcept C134018914 @default.
• W2003183205 hasConcept C15744967 @default.
• W2003183205 hasConcept C160539049 @default.
• W2003183205 hasConcept C170493617 @default.
• W2003183205 hasConcept C2776319443 @default.

• next