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- W2003190217 abstract "The application of electrochemical techniques for DNA detection is motivated by their potential to detect hybridization events in a more rapid, simplistic and cost-effective manner compared to conventional methods. Here, we present an electrochemical DNA biosensor for the specific and quantitative detection of single-stranded DNA (ssDNA). Probe oligonucleotides were immobilized onto gold electrodes by a 5′ end thiol-group linker. Following hybridization with the complementary DNA, the cobalt complex was electrochemically accumulated on the double-stranded DNA layer and the differential pulse voltammogram (DPV) for this electrode gave an electrochemical signal due to the redox reaction of [Co(phen) 3 ] 2 + / 3 + that was bound to the double-stranded DNA on the electrode, and it can sense single base-pair mismatche within the sequence of the hybridized double-stranded DNA (dsDNA)." @default.
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- W2003190217 date "2011-07-01" @default.
- W2003190217 modified "2023-09-22" @default.
- W2003190217 title "Electrochemical DNA Biosensor for the Detection of Short DNA Species by Using Compound Co(phen)<sub>3</sub><sup>2+</sup>" @default.
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- W2003190217 doi "https://doi.org/10.4028/www.scientific.net/amr.301-303.213" @default.
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