Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003190623> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2003190623 endingPage "395" @default.
- W2003190623 startingPage "383" @default.
- W2003190623 abstract "The disulfide bonding characteristics of the pig lymph node plasma membrane (PM) proteins and glycoproteins have been examined by 1- and 2-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS PAGE). Reaction of the purified PM vesicles with N-ethyl maleimide (NEM) prior to detergent solubilization was found to markedly reduce the extent of intermolecular disulfide bonding subsequently observed. Thus the blocking of free sulfhydryl groups with NEM prevented the detergent-induced disulfide bonding of numerous components, including PM-hound actin. The extent of intermolecular disulfide bonding among the NEM-pretreated PM glycoproteins purified by lentil lectin affinity chromatography was found to be relatively limited, with only 3% of the total glycoprotein present as intermolecular disulfide-bonded complexes. In contrast, the degree of intramolecular disulfide bonding revealed by a modified 1-dimensional SDS PAGE technique was quite striking. Among those polypeptides demonstrating a clearly altered mobility upon reduction was the heavy chain of class I and β-chain of class II major histocompatibility complex (MHC) antigens. The class II α-chain. however, was much less affected. These changes have been compared with those observed for proteins containing intramolecular disulfide-bonded domains of known size and number, and considered in the light of recent information on the structure of MHC antigens." @default.
- W2003190623 created "2016-06-24" @default.
- W2003190623 creator A5023164057 @default.
- W2003190623 creator A5029792933 @default.
- W2003190623 date "1983-04-01" @default.
- W2003190623 modified "2023-09-26" @default.
- W2003190623 title "Inter- and intramolecular disulfide bonding among lymphocyte plasma membrane proteins and glycoproteins" @default.
- W2003190623 cites W1510195393 @default.
- W2003190623 cites W1525066480 @default.
- W2003190623 cites W1556035179 @default.
- W2003190623 cites W1748545643 @default.
- W2003190623 cites W1963975410 @default.
- W2003190623 cites W1968082000 @default.
- W2003190623 cites W1993823140 @default.
- W2003190623 cites W2010876541 @default.
- W2003190623 cites W2029644009 @default.
- W2003190623 cites W2042708086 @default.
- W2003190623 cites W2044936649 @default.
- W2003190623 cites W2052430612 @default.
- W2003190623 cites W2058620834 @default.
- W2003190623 cites W2062132636 @default.
- W2003190623 cites W2093981261 @default.
- W2003190623 cites W2100837269 @default.
- W2003190623 cites W2157486990 @default.
- W2003190623 cites W2201082139 @default.
- W2003190623 cites W2300200268 @default.
- W2003190623 cites W49242452 @default.
- W2003190623 doi "https://doi.org/10.1016/0161-5890(83)90020-2" @default.
- W2003190623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6865956" @default.
- W2003190623 hasPublicationYear "1983" @default.
- W2003190623 type Work @default.
- W2003190623 sameAs 2003190623 @default.
- W2003190623 citedByCount "18" @default.
- W2003190623 crossrefType "journal-article" @default.
- W2003190623 hasAuthorship W2003190623A5023164057 @default.
- W2003190623 hasAuthorship W2003190623A5029792933 @default.
- W2003190623 hasConcept C101660505 @default.
- W2003190623 hasConcept C108625454 @default.
- W2003190623 hasConcept C116084860 @default.
- W2003190623 hasConcept C166950319 @default.
- W2003190623 hasConcept C178790620 @default.
- W2003190623 hasConcept C181199279 @default.
- W2003190623 hasConcept C185592680 @default.
- W2003190623 hasConcept C188027245 @default.
- W2003190623 hasConcept C27256138 @default.
- W2003190623 hasConcept C2778913249 @default.
- W2003190623 hasConcept C2779201268 @default.
- W2003190623 hasConcept C2780105360 @default.
- W2003190623 hasConcept C2910051704 @default.
- W2003190623 hasConcept C32909587 @default.
- W2003190623 hasConcept C5098756 @default.
- W2003190623 hasConcept C55493867 @default.
- W2003190623 hasConcept C71240020 @default.
- W2003190623 hasConcept C75079739 @default.
- W2003190623 hasConceptScore W2003190623C101660505 @default.
- W2003190623 hasConceptScore W2003190623C108625454 @default.
- W2003190623 hasConceptScore W2003190623C116084860 @default.
- W2003190623 hasConceptScore W2003190623C166950319 @default.
- W2003190623 hasConceptScore W2003190623C178790620 @default.
- W2003190623 hasConceptScore W2003190623C181199279 @default.
- W2003190623 hasConceptScore W2003190623C185592680 @default.
- W2003190623 hasConceptScore W2003190623C188027245 @default.
- W2003190623 hasConceptScore W2003190623C27256138 @default.
- W2003190623 hasConceptScore W2003190623C2778913249 @default.
- W2003190623 hasConceptScore W2003190623C2779201268 @default.
- W2003190623 hasConceptScore W2003190623C2780105360 @default.
- W2003190623 hasConceptScore W2003190623C2910051704 @default.
- W2003190623 hasConceptScore W2003190623C32909587 @default.
- W2003190623 hasConceptScore W2003190623C5098756 @default.
- W2003190623 hasConceptScore W2003190623C55493867 @default.
- W2003190623 hasConceptScore W2003190623C71240020 @default.
- W2003190623 hasConceptScore W2003190623C75079739 @default.
- W2003190623 hasIssue "4" @default.
- W2003190623 hasLocation W20031906231 @default.
- W2003190623 hasLocation W20031906232 @default.
- W2003190623 hasOpenAccess W2003190623 @default.
- W2003190623 hasPrimaryLocation W20031906231 @default.
- W2003190623 hasRelatedWork W1572699451 @default.
- W2003190623 hasRelatedWork W2003190623 @default.
- W2003190623 hasRelatedWork W2043297070 @default.
- W2003190623 hasRelatedWork W2048664314 @default.
- W2003190623 hasRelatedWork W2064891358 @default.
- W2003190623 hasRelatedWork W2084077926 @default.
- W2003190623 hasRelatedWork W2107402292 @default.
- W2003190623 hasRelatedWork W2117141996 @default.
- W2003190623 hasRelatedWork W2312473640 @default.
- W2003190623 hasRelatedWork W4233182505 @default.
- W2003190623 hasVolume "20" @default.
- W2003190623 isParatext "false" @default.
- W2003190623 isRetracted "false" @default.
- W2003190623 magId "2003190623" @default.
- W2003190623 workType "article" @default.