FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003190767> ?p ?o ?g. }

• W2003190767 endingPage "4804" @default.
• W2003190767 startingPage "4789" @default.
• W2003190767 abstract "Although a loss-of-function mutation has been identified in familial Parkinson's disease PARK7, the wild-type of DJ-1 is known to act as an oxidative stress sensor in neuronal cells. Recently, we identified UCP0045037 as a compound that bound to the reduced form of DJ-1 by in silico virtual screening. In this study, we determined the neuroprotective effects of UCP0045037 against focal cerebral ischemia-induced neurodegeneration in rats. Hydrogen peroxide-induced cell death was significantly inhibited by UCP0045037 in both rat mesencephalic dopaminergic neurons and human normal SH-SY5Y cells. In contrast, DJ-1-knockdown SH-SY5Y cells lost the protective activity of UCP0045037. These results suggest that UCP0045037 interacts with endogenous DJ-1 and produces a neuroprotective response." @default.
• W2003190767 created "2016-06-24" @default.
• W2003190767 creator A5000059241 @default.
• W2003190767 creator A5024903237 @default.
• W2003190767 creator A5026275950 @default.
• W2003190767 creator A5032064265 @default.
• W2003190767 creator A5073735444 @default.
• W2003190767 creator A5081249068 @default.
• W2003190767 creator A5081384952 @default.
• W2003190767 creator A5090553551 @default.
• W2003190767 date "2009-11-05" @default.
• W2003190767 modified "2023-10-02" @default.
• W2003190767 title "Oxidative Neurodegeneration Is Prevented by UCP0045037, an Allosteric Modulator for the Reduced Form of DJ-1, a Wild-Type of Familial Parkinson’s Disease-Linked PARK7" @default.
• W2003190767 cites W1484252393 @default.
• W2003190767 cites W1485984810 @default.
• W2003190767 cites W1930841657 @default.
• W2003190767 cites W1967603366 @default.
• W2003190767 cites W1968413329 @default.
• W2003190767 cites W1971120748 @default.
• W2003190767 cites W1976393002 @default.
• W2003190767 cites W1978163054 @default.
• W2003190767 cites W1978404200 @default.
• W2003190767 cites W1979849865 @default.
• W2003190767 cites W1990847293 @default.
• W2003190767 cites W1993250284 @default.
• W2003190767 cites W1994315639 @default.
• W2003190767 cites W1994715640 @default.
• W2003190767 cites W1999366771 @default.
• W2003190767 cites W1999469282 @default.
• W2003190767 cites W2010714560 @default.
• W2003190767 cites W2012112859 @default.
• W2003190767 cites W2013938692 @default.
• W2003190767 cites W2024885339 @default.
• W2003190767 cites W2037286236 @default.
• W2003190767 cites W2068635825 @default.
• W2003190767 cites W2070766926 @default.
• W2003190767 cites W2072877021 @default.
• W2003190767 cites W2075542239 @default.
• W2003190767 cites W2076196975 @default.
• W2003190767 cites W2096991937 @default.
• W2003190767 cites W2104382960 @default.
• W2003190767 cites W2109747317 @default.
• W2003190767 cites W2136347558 @default.
• W2003190767 cites W2145664571 @default.
• W2003190767 cites W2146434163 @default.
• W2003190767 cites W2169185329 @default.
• W2003190767 cites W2170748127 @default.
• W2003190767 doi "https://doi.org/10.3390/ijms10114789" @default.
• W2003190767 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2808011" @default.
• W2003190767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20087465" @default.
• W2003190767 hasPublicationYear "2009" @default.
• W2003190767 type Work @default.
• W2003190767 sameAs 2003190767 @default.
• W2003190767 citedByCount "18" @default.
• W2003190767 countsByYear W20031907672012 @default.
• W2003190767 countsByYear W20031907672013 @default.
• W2003190767 countsByYear W20031907672015 @default.
• W2003190767 countsByYear W20031907672016 @default.
• W2003190767 countsByYear W20031907672017 @default.
• W2003190767 countsByYear W20031907672019 @default.
• W2003190767 countsByYear W20031907672021 @default.
• W2003190767 countsByYear W20031907672022 @default.
• W2003190767 crossrefType "journal-article" @default.
• W2003190767 hasAuthorship W2003190767A5000059241 @default.
• W2003190767 hasAuthorship W2003190767A5024903237 @default.
• W2003190767 hasAuthorship W2003190767A5026275950 @default.
• W2003190767 hasAuthorship W2003190767A5032064265 @default.
• W2003190767 hasAuthorship W2003190767A5073735444 @default.
• W2003190767 hasAuthorship W2003190767A5081249068 @default.
• W2003190767 hasAuthorship W2003190767A5081384952 @default.
• W2003190767 hasAuthorship W2003190767A5090553551 @default.
• W2003190767 hasBestOaLocation W20031907671 @default.
• W2003190767 hasConcept C104317684 @default.
• W2003190767 hasConcept C126322002 @default.
• W2003190767 hasConcept C134018914 @default.
• W2003190767 hasConcept C137183658 @default.
• W2003190767 hasConcept C143065580 @default.
• W2003190767 hasConcept C169760540 @default.
• W2003190767 hasConcept C185592680 @default.
• W2003190767 hasConcept C190283241 @default.
• W2003190767 hasConcept C207583985 @default.
• W2003190767 hasConcept C25498285 @default.
• W2003190767 hasConcept C2776151105 @default.
• W2003190767 hasConcept C2776715637 @default.
• W2003190767 hasConcept C2776925932 @default.
• W2003190767 hasConcept C2779083432 @default.
• W2003190767 hasConcept C2779134260 @default.
• W2003190767 hasConcept C2779734285 @default.
• W2003190767 hasConcept C31573885 @default.
• W2003190767 hasConcept C513476851 @default.
• W2003190767 hasConcept C54355233 @default.
• W2003190767 hasConcept C55493867 @default.
• W2003190767 hasConcept C71924100 @default.
• W2003190767 hasConcept C81885089 @default.
• W2003190767 hasConcept C86803240 @default.
• W2003190767 hasConcept C95444343 @default.
• W2003190767 hasConcept C98274493 @default.
• W2003190767 hasConceptScore W2003190767C104317684 @default.

• next