FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003195877> ?p ?o ?g. }

• W2003195877 endingPage "35" @default.
• W2003195877 startingPage "29" @default.
• W2003195877 abstract "Various studies have shown that the ectoenzyme dipeptidyl peptidase IV (DP IV, CD26), expressed on T, NK and B cells in the human immune system, is involved in the regulation of DNA synthesis and cytokine production. The DP IV/CD26 was found also on mouse splenocytes and thymocytes. Here, we show that the specific DP IV inhibitors Lys[Z(NO2)]-thiazolidide, Lys[Z(NO2)]-pyrrolidide inhibit DNA synthesis as well as production of IL-2, IL-6 and IL-10 of PHA-stimulated mouse splenocytes and Con A-stimulated mouse thymocytes. Most importantly, these inhibitors induce a three to fourfold increased secretion of latent transforming growth factor β1 (TGF-β1) by mitogen-stimulated mouse immune cells, as measured with a specific TGF-β1 enzyme-linked immunosorbent assay (ELISA). These data demonstrate that CD26 plays a role also in regulation of DNA synthesis and cytokine production by murine immune cells, that the enzymatic activity is required for mediating these effects, and that TGF-β1 might have key functions in these processes." @default.
• W2003195877 created "2016-06-24" @default.
• W2003195877 creator A5011665478 @default.
• W2003195877 creator A5012518315 @default.
• W2003195877 creator A5021024316 @default.
• W2003195877 creator A5029715865 @default.
• W2003195877 creator A5032955382 @default.
• W2003195877 creator A5053203013 @default.
• W2003195877 creator A5076228795 @default.
• W2003195877 creator A5083863605 @default.
• W2003195877 date "1997-05-01" @default.
• W2003195877 modified "2023-10-16" @default.
• W2003195877 title "Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-β1 (TGF-β1) in stimulated mouse splenocytes and thymocytes" @default.
• W2003195877 cites W1943202682 @default.
• W2003195877 cites W1975189275 @default.
• W2003195877 cites W1982934705 @default.
• W2003195877 cites W1990178238 @default.
• W2003195877 cites W2007148463 @default.
• W2003195877 cites W2010216035 @default.
• W2003195877 cites W2013993175 @default.
• W2003195877 cites W2017236844 @default.
• W2003195877 cites W2020284312 @default.
• W2003195877 cites W2020771711 @default.
• W2003195877 cites W2024576568 @default.
• W2003195877 cites W2036362943 @default.
• W2003195877 cites W2041134265 @default.
• W2003195877 cites W2044428529 @default.
• W2003195877 cites W2053972082 @default.
• W2003195877 cites W2055794981 @default.
• W2003195877 cites W2079944821 @default.
• W2003195877 cites W2088511697 @default.
• W2003195877 cites W2089062394 @default.
• W2003195877 cites W2091638124 @default.
• W2003195877 cites W2095326273 @default.
• W2003195877 cites W2102887992 @default.
• W2003195877 cites W2262606490 @default.
• W2003195877 cites W2312974911 @default.
• W2003195877 cites W2324795254 @default.
• W2003195877 doi "https://doi.org/10.1016/s0165-2478(97)02716-8" @default.
• W2003195877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9436466" @default.
• W2003195877 hasPublicationYear "1997" @default.
• W2003195877 type Work @default.
• W2003195877 sameAs 2003195877 @default.
• W2003195877 citedByCount "61" @default.
• W2003195877 countsByYear W20031958772012 @default.
• W2003195877 countsByYear W20031958772013 @default.
• W2003195877 countsByYear W20031958772014 @default.
• W2003195877 countsByYear W20031958772015 @default.
• W2003195877 countsByYear W20031958772016 @default.
• W2003195877 countsByYear W20031958772017 @default.
• W2003195877 countsByYear W20031958772018 @default.
• W2003195877 countsByYear W20031958772019 @default.
• W2003195877 countsByYear W20031958772020 @default.
• W2003195877 countsByYear W20031958772022 @default.
• W2003195877 countsByYear W20031958772023 @default.
• W2003195877 crossrefType "journal-article" @default.
• W2003195877 hasAuthorship W2003195877A5011665478 @default.
• W2003195877 hasAuthorship W2003195877A5012518315 @default.
• W2003195877 hasAuthorship W2003195877A5021024316 @default.
• W2003195877 hasAuthorship W2003195877A5029715865 @default.
• W2003195877 hasAuthorship W2003195877A5032955382 @default.
• W2003195877 hasAuthorship W2003195877A5053203013 @default.
• W2003195877 hasAuthorship W2003195877A5076228795 @default.
• W2003195877 hasAuthorship W2003195877A5083863605 @default.
• W2003195877 hasConcept C118131993 @default.
• W2003195877 hasConcept C134018914 @default.
• W2003195877 hasConcept C153911025 @default.
• W2003195877 hasConcept C181199279 @default.
• W2003195877 hasConcept C185592680 @default.
• W2003195877 hasConcept C189976730 @default.
• W2003195877 hasConcept C203014093 @default.
• W2003195877 hasConcept C2778690821 @default.
• W2003195877 hasConcept C2781469919 @default.
• W2003195877 hasConcept C49039625 @default.
• W2003195877 hasConcept C552990157 @default.
• W2003195877 hasConcept C55493867 @default.
• W2003195877 hasConcept C64241487 @default.
• W2003195877 hasConcept C86803240 @default.
• W2003195877 hasConcept C8891405 @default.
• W2003195877 hasConcept C95444343 @default.
• W2003195877 hasConceptScore W2003195877C118131993 @default.
• W2003195877 hasConceptScore W2003195877C134018914 @default.
• W2003195877 hasConceptScore W2003195877C153911025 @default.
• W2003195877 hasConceptScore W2003195877C181199279 @default.
• W2003195877 hasConceptScore W2003195877C185592680 @default.
• W2003195877 hasConceptScore W2003195877C189976730 @default.
• W2003195877 hasConceptScore W2003195877C203014093 @default.
• W2003195877 hasConceptScore W2003195877C2778690821 @default.
• W2003195877 hasConceptScore W2003195877C2781469919 @default.
• W2003195877 hasConceptScore W2003195877C49039625 @default.
• W2003195877 hasConceptScore W2003195877C552990157 @default.
• W2003195877 hasConceptScore W2003195877C55493867 @default.
• W2003195877 hasConceptScore W2003195877C64241487 @default.
• W2003195877 hasConceptScore W2003195877C86803240 @default.
• W2003195877 hasConceptScore W2003195877C8891405 @default.
• W2003195877 hasConceptScore W2003195877C95444343 @default.
• W2003195877 hasIssue "1" @default.
• W2003195877 hasLocation W20031958771 @default.

• next