Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003202289> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2003202289 endingPage "404" @default.
- W2003202289 startingPage "399" @default.
- W2003202289 abstract "The performance of the saphenous vein as a bypass conduit in myocardial revascularisation may, in part, be determined by its vascular reactivity. The present study investigates whether the choice of peri-operative storage solution influences the response of this vessel to a range of vasoconstrictors and vasodilators. Saphenous vein ring segments (210) were obtained from 24 patients undergoing coronary artery bypass surgery, and following a 1 h incubation in either (1) heparinised blood, (2) heparinised saline, (3) 199-TC solution, (4) St. Thomas' cardioplegic solution or (5) plasma-lyte solution, rings of vein were set up as organ bath preparations. The relative magnitude of control constrictor response was: noradrenaline = 5-hydroxytryptamine > or = dopamine > histamine > acetylcholine. There was a significantly different (P < 0.05) enhanced response to noradrenaline and 5-hydroxytryptamine in segments stored in heparinised saline compared to 199-TC; similarly, dopamine and noradrenaline responses were significantly potentiated (P < 0.05) following storage in heparinised saline compared to cardioplegia. Storage in plasma-lyte enhanced the response significantly storage in heparinised saline compared to cardioplegia. Storage in plasma-lyte enhanced the response significantly (P < 0.05) to acetylcholine alone. None of the solutions had a significant effect on the potency (EC50) of the constrictors. Relaxations of pre-constricted segments were recorded to acetylcholine and sodium nitroprusside, but there was no difference in efficacy or potency in these responses following storage in the different solutions. This study demonstrates that the choice of peri-operative storage solution may influence the vascular reactivity of the human saphenous vein." @default.
- W2003202289 created "2016-06-24" @default.
- W2003202289 creator A5011158638 @default.
- W2003202289 creator A5015497893 @default.
- W2003202289 creator A5043729176 @default.
- W2003202289 creator A5060235077 @default.
- W2003202289 creator A5083945230 @default.
- W2003202289 date "1993-01-01" @default.
- W2003202289 modified "2023-10-18" @default.
- W2003202289 title "Effect of peri-operative storage solution on the vascular reactivity of the human saphenous vein" @default.
- W2003202289 cites W183258888 @default.
- W2003202289 cites W1987343960 @default.
- W2003202289 cites W2002995639 @default.
- W2003202289 cites W2008657094 @default.
- W2003202289 cites W2064865713 @default.
- W2003202289 cites W2101070553 @default.
- W2003202289 cites W2331162989 @default.
- W2003202289 cites W2397721637 @default.
- W2003202289 cites W2403101743 @default.
- W2003202289 cites W2408484286 @default.
- W2003202289 cites W2398484137 @default.
- W2003202289 doi "https://doi.org/10.1016/1010-7940(93)90002-s" @default.
- W2003202289 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8398185" @default.
- W2003202289 hasPublicationYear "1993" @default.
- W2003202289 type Work @default.
- W2003202289 sameAs 2003202289 @default.
- W2003202289 citedByCount "20" @default.
- W2003202289 countsByYear W20032022892012 @default.
- W2003202289 countsByYear W20032022892014 @default.
- W2003202289 countsByYear W20032022892015 @default.
- W2003202289 countsByYear W20032022892016 @default.
- W2003202289 countsByYear W20032022892017 @default.
- W2003202289 countsByYear W20032022892018 @default.
- W2003202289 countsByYear W20032022892019 @default.
- W2003202289 countsByYear W20032022892020 @default.
- W2003202289 countsByYear W20032022892022 @default.
- W2003202289 crossrefType "journal-article" @default.
- W2003202289 hasAuthorship W2003202289A5011158638 @default.
- W2003202289 hasAuthorship W2003202289A5015497893 @default.
- W2003202289 hasAuthorship W2003202289A5043729176 @default.
- W2003202289 hasAuthorship W2003202289A5060235077 @default.
- W2003202289 hasAuthorship W2003202289A5083945230 @default.
- W2003202289 hasConcept C120770815 @default.
- W2003202289 hasConcept C126322002 @default.
- W2003202289 hasConcept C185592680 @default.
- W2003202289 hasConcept C202751555 @default.
- W2003202289 hasConcept C2775910092 @default.
- W2003202289 hasConcept C2776820930 @default.
- W2003202289 hasConcept C2777202286 @default.
- W2003202289 hasConcept C2777397205 @default.
- W2003202289 hasConcept C2777663904 @default.
- W2003202289 hasConcept C2779395532 @default.
- W2003202289 hasConcept C2779610285 @default.
- W2003202289 hasConcept C2992686903 @default.
- W2003202289 hasConcept C42219234 @default.
- W2003202289 hasConcept C519581460 @default.
- W2003202289 hasConcept C55493867 @default.
- W2003202289 hasConcept C57992300 @default.
- W2003202289 hasConcept C71924100 @default.
- W2003202289 hasConceptScore W2003202289C120770815 @default.
- W2003202289 hasConceptScore W2003202289C126322002 @default.
- W2003202289 hasConceptScore W2003202289C185592680 @default.
- W2003202289 hasConceptScore W2003202289C202751555 @default.
- W2003202289 hasConceptScore W2003202289C2775910092 @default.
- W2003202289 hasConceptScore W2003202289C2776820930 @default.
- W2003202289 hasConceptScore W2003202289C2777202286 @default.
- W2003202289 hasConceptScore W2003202289C2777397205 @default.
- W2003202289 hasConceptScore W2003202289C2777663904 @default.
- W2003202289 hasConceptScore W2003202289C2779395532 @default.
- W2003202289 hasConceptScore W2003202289C2779610285 @default.
- W2003202289 hasConceptScore W2003202289C2992686903 @default.
- W2003202289 hasConceptScore W2003202289C42219234 @default.
- W2003202289 hasConceptScore W2003202289C519581460 @default.
- W2003202289 hasConceptScore W2003202289C55493867 @default.
- W2003202289 hasConceptScore W2003202289C57992300 @default.
- W2003202289 hasConceptScore W2003202289C71924100 @default.
- W2003202289 hasIssue "8" @default.
- W2003202289 hasLocation W20032022891 @default.
- W2003202289 hasLocation W20032022892 @default.
- W2003202289 hasOpenAccess W2003202289 @default.
- W2003202289 hasPrimaryLocation W20032022891 @default.
- W2003202289 hasRelatedWork W107947605 @default.
- W2003202289 hasRelatedWork W1978804120 @default.
- W2003202289 hasRelatedWork W2004283605 @default.
- W2003202289 hasRelatedWork W2006842018 @default.
- W2003202289 hasRelatedWork W2021947224 @default.
- W2003202289 hasRelatedWork W2033451262 @default.
- W2003202289 hasRelatedWork W2090036907 @default.
- W2003202289 hasRelatedWork W2165948827 @default.
- W2003202289 hasRelatedWork W2405166251 @default.
- W2003202289 hasRelatedWork W3149708726 @default.
- W2003202289 hasVolume "7" @default.
- W2003202289 isParatext "false" @default.
- W2003202289 isRetracted "false" @default.
- W2003202289 magId "2003202289" @default.
- W2003202289 workType "article" @default.