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- W2003202813 abstract "Impaired renal function has been suggested to significantly impact plasma midregional proADM (MR-proADM) level. The aim of this study was to assess whether improvement of renal function after living kidney transplantation has an impact on plasma MR-proADM-like immunoreactive substance (IS) level. Eleven patients with end-stage renal disease (ESRD) who were scheduled to undergo the first living kidney allograft transplantation were enrolled. Plasma MR-proADM-IS levels were measured before and 3, 7, 10, 14, 21, 30, 60 and 90 days after kidney transplantation. Plasma MR-proADM-IS level decreased significantly from day 3 after kidney transplantation compared to before kidney transplantation. A significant negative correlation was observed between creatinine clearance and plasma MR-proADM-IS level from before to 90 days after kidney transplantation (rs=-0.70, p<0.0001). These results suggest that recovery of kidney function after kidney transplantation may lead to decrease in plasma MR-proADM level in patients with ESRD, and that plasma MR-proADM level may depend largely on renal function." @default.
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- W2003202813 date "2013-05-01" @default.
- W2003202813 modified "2023-10-18" @default.
- W2003202813 title "Significant decrease in plasma midregional proadrenomedullin level in patients with end-stage renal disease after living kidney transplantation" @default.
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- W2003202813 doi "https://doi.org/10.1016/j.peptides.2013.03.005" @default.
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