Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003206226> ?p ?o ?g. }
- W2003206226 endingPage "136" @default.
- W2003206226 startingPage "129" @default.
- W2003206226 abstract "Tetanus toxin contains a metal-binding site for zinc, located in its light chain. The sequence accounting for Zn fixation is part of a predicted amphipathic helical secondary structure and corresponds to a putative T cell epitope according to Rothbard and Taylor (EMBO J. 7, 93–100, 1988). In this paper, we analyse the antigenic properties of two synthetic peptides (233–248 = P12 and 225–243 = P13) containing the Zn binding sequence. Our results show that peptide P13 contains a B and T epitope. The B epitope seems to be immuno-dominant whether the T epitope is at least DR2 restricted. Zn binding on P13 leads to a decrease in its recognition by both antibodies and T lymphocytes." @default.
- W2003206226 created "2016-06-24" @default.
- W2003206226 creator A5018858147 @default.
- W2003206226 creator A5033552007 @default.
- W2003206226 creator A5039426717 @default.
- W2003206226 creator A5053053338 @default.
- W2003206226 creator A5055113610 @default.
- W2003206226 date "1993-02-01" @default.
- W2003206226 modified "2023-09-27" @default.
- W2003206226 title "Involvement of the Zn-Binding region of tetanus toxin in B and T recognition. Influence of Zn fixation" @default.
- W2003206226 cites W1538232203 @default.
- W2003206226 cites W153972386 @default.
- W2003206226 cites W1585576609 @default.
- W2003206226 cites W1841868345 @default.
- W2003206226 cites W1885543154 @default.
- W2003206226 cites W1966335045 @default.
- W2003206226 cites W1971193715 @default.
- W2003206226 cites W1975304761 @default.
- W2003206226 cites W1977595200 @default.
- W2003206226 cites W1984547849 @default.
- W2003206226 cites W2006592829 @default.
- W2003206226 cites W2013137776 @default.
- W2003206226 cites W2017675208 @default.
- W2003206226 cites W2021807514 @default.
- W2003206226 cites W2038760963 @default.
- W2003206226 cites W2046542943 @default.
- W2003206226 cites W2059126503 @default.
- W2003206226 cites W2061721681 @default.
- W2003206226 cites W2094090519 @default.
- W2003206226 cites W2094886338 @default.
- W2003206226 cites W2101367047 @default.
- W2003206226 cites W2111817213 @default.
- W2003206226 cites W2119586900 @default.
- W2003206226 cites W2156687630 @default.
- W2003206226 cites W2161097693 @default.
- W2003206226 cites W2168674696 @default.
- W2003206226 doi "https://doi.org/10.1016/0161-5890(93)90084-o" @default.
- W2003206226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7679184" @default.
- W2003206226 hasPublicationYear "1993" @default.
- W2003206226 type Work @default.
- W2003206226 sameAs 2003206226 @default.
- W2003206226 citedByCount "10" @default.
- W2003206226 crossrefType "journal-article" @default.
- W2003206226 hasAuthorship W2003206226A5018858147 @default.
- W2003206226 hasAuthorship W2003206226A5033552007 @default.
- W2003206226 hasAuthorship W2003206226A5039426717 @default.
- W2003206226 hasAuthorship W2003206226A5053053338 @default.
- W2003206226 hasAuthorship W2003206226A5055113610 @default.
- W2003206226 hasConcept C104317684 @default.
- W2003206226 hasConcept C107824862 @default.
- W2003206226 hasConcept C146249460 @default.
- W2003206226 hasConcept C153911025 @default.
- W2003206226 hasConcept C159047783 @default.
- W2003206226 hasConcept C159654299 @default.
- W2003206226 hasConcept C178790620 @default.
- W2003206226 hasConcept C185592680 @default.
- W2003206226 hasConcept C195616568 @default.
- W2003206226 hasConcept C22070199 @default.
- W2003206226 hasConcept C2777367657 @default.
- W2003206226 hasConcept C2778112365 @default.
- W2003206226 hasConcept C2779281246 @default.
- W2003206226 hasConcept C2779841045 @default.
- W2003206226 hasConcept C535196362 @default.
- W2003206226 hasConcept C54355233 @default.
- W2003206226 hasConcept C55493867 @default.
- W2003206226 hasConcept C86803240 @default.
- W2003206226 hasConceptScore W2003206226C104317684 @default.
- W2003206226 hasConceptScore W2003206226C107824862 @default.
- W2003206226 hasConceptScore W2003206226C146249460 @default.
- W2003206226 hasConceptScore W2003206226C153911025 @default.
- W2003206226 hasConceptScore W2003206226C159047783 @default.
- W2003206226 hasConceptScore W2003206226C159654299 @default.
- W2003206226 hasConceptScore W2003206226C178790620 @default.
- W2003206226 hasConceptScore W2003206226C185592680 @default.
- W2003206226 hasConceptScore W2003206226C195616568 @default.
- W2003206226 hasConceptScore W2003206226C22070199 @default.
- W2003206226 hasConceptScore W2003206226C2777367657 @default.
- W2003206226 hasConceptScore W2003206226C2778112365 @default.
- W2003206226 hasConceptScore W2003206226C2779281246 @default.
- W2003206226 hasConceptScore W2003206226C2779841045 @default.
- W2003206226 hasConceptScore W2003206226C535196362 @default.
- W2003206226 hasConceptScore W2003206226C54355233 @default.
- W2003206226 hasConceptScore W2003206226C55493867 @default.
- W2003206226 hasConceptScore W2003206226C86803240 @default.
- W2003206226 hasIssue "2" @default.
- W2003206226 hasLocation W20032062261 @default.
- W2003206226 hasLocation W20032062262 @default.
- W2003206226 hasOpenAccess W2003206226 @default.
- W2003206226 hasPrimaryLocation W20032062261 @default.
- W2003206226 hasRelatedWork W2073947318 @default.
- W2003206226 hasRelatedWork W2091858072 @default.
- W2003206226 hasRelatedWork W2162746251 @default.
- W2003206226 hasRelatedWork W2399973061 @default.
- W2003206226 hasRelatedWork W2406591841 @default.
- W2003206226 hasRelatedWork W2409602088 @default.
- W2003206226 hasRelatedWork W2779574772 @default.
- W2003206226 hasRelatedWork W2952763657 @default.
- W2003206226 hasRelatedWork W2952897012 @default.